TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 21 November 1, 2011
__________________________________________________________
TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________
None submitted for this issue.
__________________________________________________________
UPCOMING MEETINGS & EVENTS
The 6th International Conference on Thrombosis and Hemostasis Issues in Cancer will be held in Bergamo, Italy, April 20-22, 2012. Online registration and abstract submission is now available. The abstract submission deadline is November 30th, 2011. For more information and to see the preliminary program, go to:
http://www.icthic.com/
* * * * * * * * * * *
Save the date:
6th Symposium on Hemostasis with Special Focus on Factor VIIa and Tissue Factor -- Hemostasis and Beyond will be held at the Carolina Inn, Chapel Hill, NC May 3-5, 2012. The link to the brochure and registration form should be available in December.
__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
__________________________________________________________
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 21 November 1, 2011
(The next issue will be on November 15, 2011)
TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________
PAPERS IN PRESS
__________________________________________________________
UPCOMING MEETINGS & EVENTS
The 6th International Conference on Thrombosis and Hemostasis Issues in Cancer will be held in Bergamo, Italy, April 20-22, 2012. Online registration and abstract submission is now available. The abstract submission deadline is November 30th, 2011. For more information and to see the preliminary program, go to:
http://www.icthic.com/
* * * * * * * * * * *
Save the date:
6th Symposium on Hemostasis with Special Focus on Factor VIIa and Tissue Factor -- Hemostasis and Beyond will be held at the Carolina Inn, Chapel Hill, NC May 3-5, 2012. The link to the brochure and registration form should be available in December.
__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1TmEifV2v36Aj7jVbb-dCua/
Badeanlou L, Furlan-Freguia C, Yang G, Ruf W, Samad F (2011) Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation. Nat Med.
http://www.ncbi.nlm.nih.gov/pubmed/22019885
Balandina AN, Shibeko AM, Kireev DA, Novikova AA, Shmirev, II, Panteleev MA, Ataullakhanov FI (2011) Positive Feedback Loops for Factor V and Factor VII Activation Supply Sensitivity to Local Surface Tissue Factor Density During Blood Coagulation. Biophys J 101:1816-1824.
http://www.ncbi.nlm.nih.gov/pubmed/22004734
Benlakhal F, Mura T, Schved JF, Giansily-Blaizot M (2011) A retrospective analysis of 157 surgical procedures performed without replacement therapy in 83 unrelated factor VII-deficient patients. J Thromb Haemost 9:1149-1156.
http://www.ncbi.nlm.nih.gov/pubmed/21486425
Bhagirath VC, O'Malley L, Crowther MA (2011) Management of bleeding complications in the anticoagulated patient. Semin Hematol 48:285-294.
http://www.ncbi.nlm.nih.gov/pubmed/22000094
Chen D, Shrivastava S, Ma L, Tham EL, Abrahams J, Coe JD, . . . Dorling A (2011) Inhibition of Thrombin Receptor Signaling on alpha-Smooth Muscle Actin+ CD34+ Progenitors Leads to Repair After Murine Immune Vascular Injury. Arterioscler Thromb Vasc Biol.
http://www.ncbi.nlm.nih.gov/pubmed/22034512
Christensen MC, Banner C, Lefering R, Vallejo-Torres L, Morris S (2011) Quality of life after severe trauma: results from the global trauma trial with recombinant Factor VII. J Trauma 70:1524-1531.
http://www.ncbi.nlm.nih.gov/pubmed/21378585
Cocco E, Varughese J, Buza N, Bellone S, Glasgow M, Bellone M, . . . Santin AD (2011) Expression of tissue factor in adenocarcinoma and squamous cell carcinoma of the uterine cervix: implications for immunotherapy with hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor. BMC Cancer 11:263.
http://www.ncbi.nlm.nih.gov/pubmed/21693061
Davalos D, Akassoglou K (2011) Fibrinogen as a key regulator of inflammation in disease. Semin Immunopathol.
http://www.ncbi.nlm.nih.gov/pubmed/22037947
Dunne B, Xiao P, Andrews D (2011) Successful Use of Factor VIIa to Control Life-threatening Post-operative Haemorrhage in a Patient on Extra-Corporeal Membrane Oxygenation. Heart Lung Circ.
http://www.ncbi.nlm.nih.gov/pubmed/22036715
Dutton RP, Parr M, Tortella BJ, Champion HR, Bernard GR, Boffard K, . . . Hauser CJ (2011) Recombinant activated factor VII safety in trauma patients: results from the CONTROL trial. J Trauma 71:12-19.
http://www.ncbi.nlm.nih.gov/pubmed/21610529
Fischer TH, Nichols TC, Scull CM, Smith CJ, Demcheva M (2011) Poly-N-acetylglucosamine fibers amplify the effectiveness of recombinant factor VIIA on clot formation in hemophilia B canine blood. J Trauma 71:S171-175.
http://www.ncbi.nlm.nih.gov/pubmed/21814114
Gambone JE, Owens Iii AP, Mackman N (2011) Comment on "Tissue factor-dependent chemokine production aggravates experimental colitis'. Mol Med.
http://www.ncbi.nlm.nih.gov/pubmed/22027905
Gardiner C, Tannetta DS, Simms CA, Harrison P, Redman CW, Sargent IL (2011) Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity. PLoS One 6:e26313.
http://www.ncbi.nlm.nih.gov/pubmed/22022598
Gessler F, Voss V, Seifert V, Gerlach R, Kogel D (2011) Knockdown of TFPI-2 promotes migration and invasion of glioma cells. Neurosci Lett 497:49-54.
http://www.ncbi.nlm.nih.gov/pubmed/21530612
Ghanny S, Warkentin TE, Crowther MA (2011) Reversing Anticoagulant Therapy. Curr Drug Discov Technol.
http://www.ncbi.nlm.nih.gov/pubmed/22023256
Huber AW, Raio L, Alberio L, Ghezzi F, Surbek DV (2011) Recombinant human factor VIIa prevents hysterectomy in severe postpartum hemorrhage: single center study. J Perinat Med.
http://www.ncbi.nlm.nih.gov/pubmed/22017328
Khorana AA (2011) Risk assessment and prophylaxis for VTE in cancer patients. J Natl Compr Canc Netw 9:789-797.
http://www.ncbi.nlm.nih.gov/pubmed/21715725
Krisl JC, Meadows HE, Greenberg CS, Mazur JE (2011) Clinical Usefulness of Recombinant Activated Factor VII in Patients with Liver Failure Undergoing Invasive Procedures. Ann Pharmacother 45:1433-1438.
http://www.ncbi.nlm.nih.gov/pubmed/22009992
Lee BJ, Kim JH, Woo SH, Kim DH, Yu YS (2011) Tissue factor is involved in retinoblastoma cell proliferation via both the Akt and extracellular signal-regulated kinase pathways. Oncol Rep 26:665-670.
http://www.ncbi.nlm.nih.gov/pubmed/21617868
Lesperance RN, Lehmann RK, Harold DM, Beekley AC, Sebesta JA, Martin MJ (2011) Recombinant Factor VIIa is Effective at Reversing Coagulopathy in a Lactic Acidosis Model. J Trauma.
http://www.ncbi.nlm.nih.gov/pubmed/22002618
Lockwood CJ (2011) Mechanisms of normal and abnormal endometrial bleeding. Menopause 18:408-411.
http://www.ncbi.nlm.nih.gov/pubmed/21499503
Mackman N, Davis GE (2011) Blood coagulation and blood vessel development: is tissue factor the missing link? Arterioscler Thromb Vasc Biol 31:2364-2366.
http://www.ncbi.nlm.nih.gov/pubmed/22011746
Mazzolai L, Bouzourene K, Hayoz D, Dignat-George F, Liu JW, Bounameaux H, . . . Kruithof EK (2011) Characterization of human late outgrowth endothelial progenitor-derived cells under various flow conditions. J Vasc Res 48:443-451.
http://www.ncbi.nlm.nih.gov/pubmed/21625177
Meadows HB, Krisl JC, Greenberg CS, Mazur JE (2011) The Use of Activated Recombinant Factor VII in a Patient with Fulminant Hepatic Failure Requiring Placement of an Intracranial Pressure Monitor. Ann Pharmacother 45:e60.
http://www.ncbi.nlm.nih.gov/pubmed/22028416
Mo X, Hao Y, Yang X, Chen S, Lu X, Gu D (2011) Association between polymorphisms in the coagulation factor VII gene and coronary heart disease risk in different ethnicities: a meta-analysis. BMC Med Genet 12:107.
http://www.ncbi.nlm.nih.gov/pubmed/21838885
Morfini M, Jimenez-Yuste V, Eichler H, Fischer R, Kirchmaier CM, Scharling B, Bjerre J (2011) Pharmacokinetic properties of two different recombinant activated factor VII formulations. Haemophilia.
http://www.ncbi.nlm.nih.gov/pubmed/21999231
Ostergaard H, Bjelke JR, Hansen L, Petersen LC, Pedersen AA, Elm T, . . . Tranholm M (2011) Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide. Blood 118:2333-2341.
http://www.ncbi.nlm.nih.gov/pubmed/21700771
Puy C, Hermida J, Montes R (2011) Factor X and factor VII binding to endothelial protein C receptor differs between species. J Thromb Haemost 9:1255-1257.
http://www.ncbi.nlm.nih.gov/pubmed/21489130
Queiroz KC, Spek CA (2011) Response to Comment on "Tissue factor-dependent chemokine production aggravates experimental colitis'. Mol Med.
http://www.ncbi.nlm.nih.gov/pubmed/22027904
Rice TW, Morris S, Tortella BJ, Wheeler AP, Christensen MC (2011) Deviations from evidence based clinical management guidelines increase mortality in critically injured trauma patients. Crit Care Med.
http://www.ncbi.nlm.nih.gov/pubmed/22036858
Rochier A, Nixon A, Yamashita N, Abe R, Madri JA, Sumpio BE (2011) Laminar shear, but not orbital shear, has a synergistic effect with thrombin stimulation on tissue factor expression in human umbilical vein endothelial cells. J Vasc Surg 54:480-488.
http://www.ncbi.nlm.nih.gov/pubmed/21367569
Scola MR, Nichols TC, Zhu H, Caughey MC, Merricks EP, Raymer RA, . . . Gallippi CM (2011) ARFI Ultrasound Monitoring of Hemorrhage and Hemostasis In Vivo in Canine von Willebrand Disease and Hemophilia. Ultrasound Med Biol.
http://www.ncbi.nlm.nih.gov/pubmed/22033127
Sossdorf M, Otto GP, Claus RA, Gabriel HH, Losche W (2011) Cell-derived microparticles promote coagulation after moderate exercise. Med Sci Sports Exerc 43:1169-1176.
http://www.ncbi.nlm.nih.gov/pubmed/21131870
Stephan S, Schwarz H, Haude-Barten A, Sidelmann JJ, Fischer B, Althaus H, . . . Vitzthum F (2011) Direct chromogenic substrate immuno-capture activity assay for testing of factor VII-activating protease. Clin Chem Lab Med 49:1199-1204.
http://www.ncbi.nlm.nih.gov/pubmed/21663569
Svensson KJ, Kucharzewska P, Christianson HC, Skold S, Lofstedt T, Johansson MC, . . . Belting M (2011) Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells. Proc Natl Acad Sci U S A 108:13147-13152.
http://www.ncbi.nlm.nih.gov/pubmed/21788507
Tiede A, Friedrich U, Stenmo C, Allen G, Giangrande P, Goudemand J, . . . Berntorp E (2011) Safety and pharmacokinetics of subcutaneously administered recombinant activated factor VII (rFVIIa). J Thromb Haemost 9:1191-1199.
http://www.ncbi.nlm.nih.gov/pubmed/21489128
Yada K, Nogami K, Ogiwara K, Shibata M, Shima M (2011) Effects of anti-factor VIII inhibitor antibodies on factor VIIa/tissue factor-catalysed activation and inactivation of factor VIII. Thromb Haemost 105:989-998.
http://www.ncbi.nlm.nih.gov/pubmed/21437361
__________________________________________________________
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1TmEifV2v36Aj7jVbb-dCua/
Badeanlou L, Furlan-Freguia C, Yang G, Ruf W, Samad F (2011) Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation. Nat Med.
http://www.ncbi.nlm.nih.gov/pubmed/22019885
Balandina AN, Shibeko AM, Kireev DA, Novikova AA, Shmirev, II, Panteleev MA, Ataullakhanov FI (2011) Positive Feedback Loops for Factor V and Factor VII Activation Supply Sensitivity to Local Surface Tissue Factor Density During Blood Coagulation. Biophys J 101:1816-1824.
http://www.ncbi.nlm.nih.gov/pubmed/22004734
Benlakhal F, Mura T, Schved JF, Giansily-Blaizot M (2011) A retrospective analysis of 157 surgical procedures performed without replacement therapy in 83 unrelated factor VII-deficient patients. J Thromb Haemost 9:1149-1156.
http://www.ncbi.nlm.nih.gov/pubmed/21486425
Bhagirath VC, O'Malley L, Crowther MA (2011) Management of bleeding complications in the anticoagulated patient. Semin Hematol 48:285-294.
http://www.ncbi.nlm.nih.gov/pubmed/22000094
Chen D, Shrivastava S, Ma L, Tham EL, Abrahams J, Coe JD, . . . Dorling A (2011) Inhibition of Thrombin Receptor Signaling on alpha-Smooth Muscle Actin+ CD34+ Progenitors Leads to Repair After Murine Immune Vascular Injury. Arterioscler Thromb Vasc Biol.
http://www.ncbi.nlm.nih.gov/pubmed/22034512
Christensen MC, Banner C, Lefering R, Vallejo-Torres L, Morris S (2011) Quality of life after severe trauma: results from the global trauma trial with recombinant Factor VII. J Trauma 70:1524-1531.
http://www.ncbi.nlm.nih.gov/pubmed/21378585
Cocco E, Varughese J, Buza N, Bellone S, Glasgow M, Bellone M, . . . Santin AD (2011) Expression of tissue factor in adenocarcinoma and squamous cell carcinoma of the uterine cervix: implications for immunotherapy with hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor. BMC Cancer 11:263.
http://www.ncbi.nlm.nih.gov/pubmed/21693061
Davalos D, Akassoglou K (2011) Fibrinogen as a key regulator of inflammation in disease. Semin Immunopathol.
http://www.ncbi.nlm.nih.gov/pubmed/22037947
Dunne B, Xiao P, Andrews D (2011) Successful Use of Factor VIIa to Control Life-threatening Post-operative Haemorrhage in a Patient on Extra-Corporeal Membrane Oxygenation. Heart Lung Circ.
http://www.ncbi.nlm.nih.gov/pubmed/22036715
Dutton RP, Parr M, Tortella BJ, Champion HR, Bernard GR, Boffard K, . . . Hauser CJ (2011) Recombinant activated factor VII safety in trauma patients: results from the CONTROL trial. J Trauma 71:12-19.
http://www.ncbi.nlm.nih.gov/pubmed/21610529
Fischer TH, Nichols TC, Scull CM, Smith CJ, Demcheva M (2011) Poly-N-acetylglucosamine fibers amplify the effectiveness of recombinant factor VIIA on clot formation in hemophilia B canine blood. J Trauma 71:S171-175.
http://www.ncbi.nlm.nih.gov/pubmed/21814114
Gambone JE, Owens Iii AP, Mackman N (2011) Comment on "Tissue factor-dependent chemokine production aggravates experimental colitis'. Mol Med.
http://www.ncbi.nlm.nih.gov/pubmed/22027905
Gardiner C, Tannetta DS, Simms CA, Harrison P, Redman CW, Sargent IL (2011) Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity. PLoS One 6:e26313.
http://www.ncbi.nlm.nih.gov/pubmed/22022598
Gessler F, Voss V, Seifert V, Gerlach R, Kogel D (2011) Knockdown of TFPI-2 promotes migration and invasion of glioma cells. Neurosci Lett 497:49-54.
http://www.ncbi.nlm.nih.gov/pubmed/21530612
Ghanny S, Warkentin TE, Crowther MA (2011) Reversing Anticoagulant Therapy. Curr Drug Discov Technol.
http://www.ncbi.nlm.nih.gov/pubmed/22023256
Huber AW, Raio L, Alberio L, Ghezzi F, Surbek DV (2011) Recombinant human factor VIIa prevents hysterectomy in severe postpartum hemorrhage: single center study. J Perinat Med.
http://www.ncbi.nlm.nih.gov/pubmed/22017328
Khorana AA (2011) Risk assessment and prophylaxis for VTE in cancer patients. J Natl Compr Canc Netw 9:789-797.
http://www.ncbi.nlm.nih.gov/pubmed/21715725
Krisl JC, Meadows HE, Greenberg CS, Mazur JE (2011) Clinical Usefulness of Recombinant Activated Factor VII in Patients with Liver Failure Undergoing Invasive Procedures. Ann Pharmacother 45:1433-1438.
http://www.ncbi.nlm.nih.gov/pubmed/22009992
Lee BJ, Kim JH, Woo SH, Kim DH, Yu YS (2011) Tissue factor is involved in retinoblastoma cell proliferation via both the Akt and extracellular signal-regulated kinase pathways. Oncol Rep 26:665-670.
http://www.ncbi.nlm.nih.gov/pubmed/21617868
Lesperance RN, Lehmann RK, Harold DM, Beekley AC, Sebesta JA, Martin MJ (2011) Recombinant Factor VIIa is Effective at Reversing Coagulopathy in a Lactic Acidosis Model. J Trauma.
http://www.ncbi.nlm.nih.gov/pubmed/22002618
Lockwood CJ (2011) Mechanisms of normal and abnormal endometrial bleeding. Menopause 18:408-411.
http://www.ncbi.nlm.nih.gov/pubmed/21499503
Mackman N, Davis GE (2011) Blood coagulation and blood vessel development: is tissue factor the missing link? Arterioscler Thromb Vasc Biol 31:2364-2366.
http://www.ncbi.nlm.nih.gov/pubmed/22011746
Mazzolai L, Bouzourene K, Hayoz D, Dignat-George F, Liu JW, Bounameaux H, . . . Kruithof EK (2011) Characterization of human late outgrowth endothelial progenitor-derived cells under various flow conditions. J Vasc Res 48:443-451.
http://www.ncbi.nlm.nih.gov/pubmed/21625177
Meadows HB, Krisl JC, Greenberg CS, Mazur JE (2011) The Use of Activated Recombinant Factor VII in a Patient with Fulminant Hepatic Failure Requiring Placement of an Intracranial Pressure Monitor. Ann Pharmacother 45:e60.
http://www.ncbi.nlm.nih.gov/pubmed/22028416
Mo X, Hao Y, Yang X, Chen S, Lu X, Gu D (2011) Association between polymorphisms in the coagulation factor VII gene and coronary heart disease risk in different ethnicities: a meta-analysis. BMC Med Genet 12:107.
http://www.ncbi.nlm.nih.gov/pubmed/21838885
Morfini M, Jimenez-Yuste V, Eichler H, Fischer R, Kirchmaier CM, Scharling B, Bjerre J (2011) Pharmacokinetic properties of two different recombinant activated factor VII formulations. Haemophilia.
http://www.ncbi.nlm.nih.gov/pubmed/21999231
Ostergaard H, Bjelke JR, Hansen L, Petersen LC, Pedersen AA, Elm T, . . . Tranholm M (2011) Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide. Blood 118:2333-2341.
http://www.ncbi.nlm.nih.gov/pubmed/21700771
Puy C, Hermida J, Montes R (2011) Factor X and factor VII binding to endothelial protein C receptor differs between species. J Thromb Haemost 9:1255-1257.
http://www.ncbi.nlm.nih.gov/pubmed/21489130
Queiroz KC, Spek CA (2011) Response to Comment on "Tissue factor-dependent chemokine production aggravates experimental colitis'. Mol Med.
http://www.ncbi.nlm.nih.gov/pubmed/22027904
Rice TW, Morris S, Tortella BJ, Wheeler AP, Christensen MC (2011) Deviations from evidence based clinical management guidelines increase mortality in critically injured trauma patients. Crit Care Med.
http://www.ncbi.nlm.nih.gov/pubmed/22036858
Rochier A, Nixon A, Yamashita N, Abe R, Madri JA, Sumpio BE (2011) Laminar shear, but not orbital shear, has a synergistic effect with thrombin stimulation on tissue factor expression in human umbilical vein endothelial cells. J Vasc Surg 54:480-488.
http://www.ncbi.nlm.nih.gov/pubmed/21367569
Scola MR, Nichols TC, Zhu H, Caughey MC, Merricks EP, Raymer RA, . . . Gallippi CM (2011) ARFI Ultrasound Monitoring of Hemorrhage and Hemostasis In Vivo in Canine von Willebrand Disease and Hemophilia. Ultrasound Med Biol.
http://www.ncbi.nlm.nih.gov/pubmed/22033127
Sossdorf M, Otto GP, Claus RA, Gabriel HH, Losche W (2011) Cell-derived microparticles promote coagulation after moderate exercise. Med Sci Sports Exerc 43:1169-1176.
http://www.ncbi.nlm.nih.gov/pubmed/21131870
Stephan S, Schwarz H, Haude-Barten A, Sidelmann JJ, Fischer B, Althaus H, . . . Vitzthum F (2011) Direct chromogenic substrate immuno-capture activity assay for testing of factor VII-activating protease. Clin Chem Lab Med 49:1199-1204.
http://www.ncbi.nlm.nih.gov/pubmed/21663569
Svensson KJ, Kucharzewska P, Christianson HC, Skold S, Lofstedt T, Johansson MC, . . . Belting M (2011) Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells. Proc Natl Acad Sci U S A 108:13147-13152.
http://www.ncbi.nlm.nih.gov/pubmed/21788507
Tiede A, Friedrich U, Stenmo C, Allen G, Giangrande P, Goudemand J, . . . Berntorp E (2011) Safety and pharmacokinetics of subcutaneously administered recombinant activated factor VII (rFVIIa). J Thromb Haemost 9:1191-1199.
http://www.ncbi.nlm.nih.gov/pubmed/21489128
Yada K, Nogami K, Ogiwara K, Shibata M, Shima M (2011) Effects of anti-factor VIII inhibitor antibodies on factor VIIa/tissue factor-catalysed activation and inactivation of factor VIII. Thromb Haemost 105:989-998.
http://www.ncbi.nlm.nih.gov/pubmed/21437361
__________________________________________________________
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
__________________________________________________________