TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 18, No. 18 September 17, 2012
__________________________________________________________
TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________
PRODUCT ANNOUNCEMENT
Haematologic Technologies, Inc. supplies CTI Blood Collection Tubes for use in thrombin generation assays and for the basic study of the TF-dependent pathway of coagulation:
http://www.haemtech.com/Inhibitors_Substrates/CTI.htm
Contact customer service (hti AT haemtech DOT com) for additional information or simply visit our website via the links above. Please include "Trigger" in the subject line.
DISCLAIMER: Commercial product announcements appearing in TRIGGER are provided "as is" for informational purposes only. The editors of TRIGGER have not necessarily evaluated any materials from commercial suppliers described in this newsletter or on its web sites, and we certainly are not endorsing any specific suppliers or products. Furthermore, the editors receive no revenues from any source in the course of publishing TRIGGER.
__________________________________________________________
UPCOMING MEETINGS & EVENTS
http://tf7.org/meetings.htm
__________________________________________________________
PAPERS IN PRESS
None Submitted for this issue.
__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
__________________________________________________________
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 18, No. 18 September 17, 2012
(The next issue will be on October 1, 2012)
TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________
PRODUCT ANNOUNCEMENT
Haematologic Technologies, Inc. supplies CTI Blood Collection Tubes for use in thrombin generation assays and for the basic study of the TF-dependent pathway of coagulation:
http://www.haemtech.com/Inhibitors_Substrates/CTI.htm
Contact customer service (hti AT haemtech DOT com) for additional information or simply visit our website via the links above. Please include "Trigger" in the subject line.
DISCLAIMER: Commercial product announcements appearing in TRIGGER are provided "as is" for informational purposes only. The editors of TRIGGER have not necessarily evaluated any materials from commercial suppliers described in this newsletter or on its web sites, and we certainly are not endorsing any specific suppliers or products. Furthermore, the editors receive no revenues from any source in the course of publishing TRIGGER.
__________________________________________________________
UPCOMING MEETINGS & EVENTS
http://tf7.org/meetings.htm
__________________________________________________________
PAPERS IN PRESS
None Submitted for this issue.
__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1Ji6M9txtDSkbvugYhx-NOk/
Baumann Kreuziger LM, Morton CT, Dries DJ (2012) New anticoagulants: A concise review. J Trauma Acute Care Surg.
http://www.ncbi.nlm.nih.gov/pubmed/22976421
Benkwitz C, Hammer GB (2012) Thrombotic Endotracheal Tube Occlusion After Administration of Recombinant Factor VIIa. J Cardiothorac Vasc Anesth.
http://www.ncbi.nlm.nih.gov/pubmed/22959153
Bluff JE, Amarzguioui M, Slattery J, Reed MW, Brown NJ, Staton CA (2011) Anti-tissue factor short hairpin RNA inhibits breast cancer growth in vivo. Breast Cancer Res Treat 128:691-701.
http://www.ncbi.nlm.nih.gov/pubmed/20830515
Branchini A, Rizzotto L, Mariani G, Napolitano M, Lapecorella M, Giansily-Blaizot M, . . . Bernardi F (2012) Natural and engineered carboxy-terminal variants: decreased secretion and gain-of-function result in asymptomatic coagulation factor VII deficiency. Haematologica 97:705-709.
http://www.ncbi.nlm.nih.gov/pubmed/22180436
Bulato C, Radu C, Simioni P (2012) Studies on coagulation incompatibilities for xenotransplantation. Methods Mol Biol 885:71-89.
http://www.ncbi.nlm.nih.gov/pubmed/22565991
Chung JY, Yi JM, Xie R, Brown V, Lee O, Ahuja N, . . . Hewitt SM (2012) A pressure cooking-based DNA extraction from archival formalin-fixed, paraffin-embedded tissue. Anal Biochem 425:128-134.
http://www.ncbi.nlm.nih.gov/pubmed/22449494
Clark CA, Vatsyayan R, Hedner U, Esmon CT, Pendurthi UR, Rao LV (2012) Endothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/22950420
Geenen IL, Post MJ, Molin DG, Schurink GW, Maessen JG, R VO, . . . Spronk HM (2012) Coagulation on endothelial cells: The underexposed part of Virchow's Triad. Thromb Haemost 108.
http://www.ncbi.nlm.nih.gov/pubmed/22955519
Gissel M, Orfeo T, Foley JH, Butenas S (2012) Effect of BAX499 aptamer on tissue factor pathway inhibitor function and thrombin generation in models of hemophilia. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22951415
Guth MC, Kaufner L, Kleber C, von Heymann C (2012) [Therapy of Trauma-induced coagulopathy - what is the evidence?]. Anasthesiol Intensivmed Notfallmed Schmerzther 47:528-540.
http://www.ncbi.nlm.nih.gov/pubmed/22968981
Haeusler KG, Herm J, Hoppe B, Kasabov R, Malzahn U, Endres M, . . . Jungehulsing GJ (2012) Thrombophilia screening in young patients with cryptogenic stroke. Prevalence of gene polymorphisms compared to healthy blood donors and impact on secondary stroke prevention. Hamostaseologie 32:147-152.
http://www.ncbi.nlm.nih.gov/pubmed/22382799
Hajj-Chahine J (2012) eComment. Activated recombinant factor VII in intractable bleeding after cardiac surgery. Interact Cardiovasc Thorac Surg 14:698.
http://www.ncbi.nlm.nih.gov/pubmed/22589339
Higuchi Y, Kubota T, Koyanagi M, Maeda T, Feldman AM, Makino N (2012) Upregulation of anticoagulant proteins, protein S and tissue factor pathway inhibitor, in the mouse myocardium with cardio-specific TNF-alpha overexpression. Am J Physiol Heart Circ Physiol 302:H2352-2362.
http://www.ncbi.nlm.nih.gov/pubmed/22492716
Imanishi T, Akasaka T (2012) Biomarkers associated with vulnerable atheromatous plaque. Curr Med Chem 19:2588-2596.
http://www.ncbi.nlm.nih.gov/pubmed/22489722
Langer F, Bokemeyer C (2012) Crosstalk between cancer and haemostasis. Implications for cancer biology and cancer-associated thrombosis with focus on tissue factor. Hamostaseologie 32:95-104.
http://www.ncbi.nlm.nih.gov/pubmed/21792469
Lapecorella M, Napolitano M, Lucchesi A, Pisani F, Clemente K, Rizza V, . . . Di Cocco P (2012) Management of Kidney Transplantation in a Factor VII-Deficient Patient: Case Report. Transplant Proc 44:2033-2035.
http://www.ncbi.nlm.nih.gov/pubmed/22974900
Laroche M, Kutcher ME, Huang MC, Cohen MJ, Manley GT (2012) Coagulopathy after traumatic brain injury. Neurosurgery 70:1334-1345.
http://www.ncbi.nlm.nih.gov/pubmed/22307074
Lee CJ, Wu S, Bartolotti LJ, Pedersen LG (2012) Molecular dynamics simulations of the binary complex of human tissue factor (TF(1-242) ) and factor VIIa (TF(1-242) /fVIIa) on a 4:1 POPC/POPS lipid bilayer. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/22967237
Mackman N (2012) New insights into the mechanisms of venous thrombosis. J Clin Invest 122:2331-2336.
http://www.ncbi.nlm.nih.gov/pubmed/22751108
Morrissey JH, Choi SH, Smith SA (2012) Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation. Blood 119:5972-5979.
http://www.ncbi.nlm.nih.gov/pubmed/22517894
Nielsen VG, Hafner DT (2012) Freezing does not decrease carbon monoxide-mediated hypercoagulation and hypofibrinolysis in human plasma. Blood Coagul Fibrinolysis.
http://www.ncbi.nlm.nih.gov/pubmed/22964769
Peng Y, Li Q, Zhang L, Bai M, Zhang Z (2012) Peroxisome Proliferator-Activated Receptor alpha Plays an Important Role in the Expression of Monocyte Chemoattractant Protein-1 and Neointimal Hyperplasia after Vascular Injury. PPAR Res 2012:970525.
http://www.ncbi.nlm.nih.gov/pubmed/22966226
Pugh N, Jarvis GE, Koch A, Sakariassen KS, Davis B, Farndale RW (2012) The impact of factor Xa inhibition on axial dependent arterial thrombus formation triggered by a tissue factor rich surface. J Thromb Thrombolysis 33:6-15.
http://www.ncbi.nlm.nih.gov/pubmed/22120925
Reid VL, Webster NR (2012) Role of microparticles in sepsis. Br J Anaesth 109:503-513.
http://www.ncbi.nlm.nih.gov/pubmed/22952169
Reimer J, Bien S, Ameling S, Hammer E, Volker U, Hempel G, . . . Ritter CA (2012) Antineoplastic agent busulfan regulates a network of genes related to coagulation and fibrinolysis. Eur J Clin Pharmacol 68:923-935.
http://www.ncbi.nlm.nih.gov/pubmed/22286157
Rossetto V, Spiezia L, Senzolo M, Rodriguez K, Gavasso S, Woodhams B, Simioni P (2012) Factor VIIa-antithrombin complexes in patients with non-neoplastic portal vein thrombosis with and without cirrhosis. Int J Lab Hematol.
http://www.ncbi.nlm.nih.gov/pubmed/22958499
Santos MJ, Carmona-Fernandes D, Canhao H, Canas da Silva J, Fonseca JE, Gil V (2012) Early Vascular Alterations in SLE and RA Patients-A Step towards Understanding the Associated Cardiovascular Risk. PLoS One 7:e44668.
http://www.ncbi.nlm.nih.gov/pubmed/22962622
Schindhelm RK, Wondergem MJ, Admiraal J, Nap G, Boekel ET, Hani L (2012) A patient with a prolonged activated partial thromboplastin time and a deep intracerebral haemorrhage. Case Rep Neurol 4:131-136.
http://www.ncbi.nlm.nih.gov/pubmed/22949911
Solvik UO, Roraas TH, Petersen PH, Stavelin AV, Monsen G, Sandberg S (2012) Effect of coagulation factors on discrepancies in International Normalized Ratio results between instruments. Clin Chem Lab Med 50:1611-1620.
http://www.ncbi.nlm.nih.gov/pubmed/22962222
Turfan M, Poyraz F, Ozturk Kaymak A, Ergun MA, Tavil Y, Gursel T, Abaci A (2012) Plasma Levels and Distribution of Gene Polymorphisms of Factor VII in Turkish Population. Clin Appl Thromb Hemost.
http://www.ncbi.nlm.nih.gov/pubmed/22964781
Wu D, Xiong L, Wu S, Jiang M, Lian G, Wang M (2012) TFPI-2 methylation predicts poor prognosis in non-small cell lung cancer. Lung Cancer 76:106-111.
http://www.ncbi.nlm.nih.gov/pubmed/21983100
Xie H, Zhou H, Wang H, Chen D, Xia L, Wang T, Yan J (2012) Anti-beta(2)GPI/beta(2)GPI induced TF and TNF-alpha expression in monocytes involving both TLR4/MyD88 and TLR4/TRIF signaling pathways. Mol Immunol 53:246-254.
http://www.ncbi.nlm.nih.gov/pubmed/22964479
Young G, Auerswald G, Jimenez-Yuste V, Lambert T, Morfini M, Santagostino E, Blanchette V (2012) PRO-PACT: Retrospective observational study on the prophylactic use of recombinant factor VIIa in hemophilia patients with inhibitors. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22964026
__________________________________________________________
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1Ji6M9txtDSkbvugYhx-NOk/
Baumann Kreuziger LM, Morton CT, Dries DJ (2012) New anticoagulants: A concise review. J Trauma Acute Care Surg.
http://www.ncbi.nlm.nih.gov/pubmed/22976421
Benkwitz C, Hammer GB (2012) Thrombotic Endotracheal Tube Occlusion After Administration of Recombinant Factor VIIa. J Cardiothorac Vasc Anesth.
http://www.ncbi.nlm.nih.gov/pubmed/22959153
Bluff JE, Amarzguioui M, Slattery J, Reed MW, Brown NJ, Staton CA (2011) Anti-tissue factor short hairpin RNA inhibits breast cancer growth in vivo. Breast Cancer Res Treat 128:691-701.
http://www.ncbi.nlm.nih.gov/pubmed/20830515
Branchini A, Rizzotto L, Mariani G, Napolitano M, Lapecorella M, Giansily-Blaizot M, . . . Bernardi F (2012) Natural and engineered carboxy-terminal variants: decreased secretion and gain-of-function result in asymptomatic coagulation factor VII deficiency. Haematologica 97:705-709.
http://www.ncbi.nlm.nih.gov/pubmed/22180436
Bulato C, Radu C, Simioni P (2012) Studies on coagulation incompatibilities for xenotransplantation. Methods Mol Biol 885:71-89.
http://www.ncbi.nlm.nih.gov/pubmed/22565991
Chung JY, Yi JM, Xie R, Brown V, Lee O, Ahuja N, . . . Hewitt SM (2012) A pressure cooking-based DNA extraction from archival formalin-fixed, paraffin-embedded tissue. Anal Biochem 425:128-134.
http://www.ncbi.nlm.nih.gov/pubmed/22449494
Clark CA, Vatsyayan R, Hedner U, Esmon CT, Pendurthi UR, Rao LV (2012) Endothelial cell protein C receptor-mediated redistribution and tissue-level accumulation of factor VIIa. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/22950420
Geenen IL, Post MJ, Molin DG, Schurink GW, Maessen JG, R VO, . . . Spronk HM (2012) Coagulation on endothelial cells: The underexposed part of Virchow's Triad. Thromb Haemost 108.
http://www.ncbi.nlm.nih.gov/pubmed/22955519
Gissel M, Orfeo T, Foley JH, Butenas S (2012) Effect of BAX499 aptamer on tissue factor pathway inhibitor function and thrombin generation in models of hemophilia. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22951415
Guth MC, Kaufner L, Kleber C, von Heymann C (2012) [Therapy of Trauma-induced coagulopathy - what is the evidence?]. Anasthesiol Intensivmed Notfallmed Schmerzther 47:528-540.
http://www.ncbi.nlm.nih.gov/pubmed/22968981
Haeusler KG, Herm J, Hoppe B, Kasabov R, Malzahn U, Endres M, . . . Jungehulsing GJ (2012) Thrombophilia screening in young patients with cryptogenic stroke. Prevalence of gene polymorphisms compared to healthy blood donors and impact on secondary stroke prevention. Hamostaseologie 32:147-152.
http://www.ncbi.nlm.nih.gov/pubmed/22382799
Hajj-Chahine J (2012) eComment. Activated recombinant factor VII in intractable bleeding after cardiac surgery. Interact Cardiovasc Thorac Surg 14:698.
http://www.ncbi.nlm.nih.gov/pubmed/22589339
Higuchi Y, Kubota T, Koyanagi M, Maeda T, Feldman AM, Makino N (2012) Upregulation of anticoagulant proteins, protein S and tissue factor pathway inhibitor, in the mouse myocardium with cardio-specific TNF-alpha overexpression. Am J Physiol Heart Circ Physiol 302:H2352-2362.
http://www.ncbi.nlm.nih.gov/pubmed/22492716
Imanishi T, Akasaka T (2012) Biomarkers associated with vulnerable atheromatous plaque. Curr Med Chem 19:2588-2596.
http://www.ncbi.nlm.nih.gov/pubmed/22489722
Langer F, Bokemeyer C (2012) Crosstalk between cancer and haemostasis. Implications for cancer biology and cancer-associated thrombosis with focus on tissue factor. Hamostaseologie 32:95-104.
http://www.ncbi.nlm.nih.gov/pubmed/21792469
Lapecorella M, Napolitano M, Lucchesi A, Pisani F, Clemente K, Rizza V, . . . Di Cocco P (2012) Management of Kidney Transplantation in a Factor VII-Deficient Patient: Case Report. Transplant Proc 44:2033-2035.
http://www.ncbi.nlm.nih.gov/pubmed/22974900
Laroche M, Kutcher ME, Huang MC, Cohen MJ, Manley GT (2012) Coagulopathy after traumatic brain injury. Neurosurgery 70:1334-1345.
http://www.ncbi.nlm.nih.gov/pubmed/22307074
Lee CJ, Wu S, Bartolotti LJ, Pedersen LG (2012) Molecular dynamics simulations of the binary complex of human tissue factor (TF(1-242) ) and factor VIIa (TF(1-242) /fVIIa) on a 4:1 POPC/POPS lipid bilayer. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/22967237
Mackman N (2012) New insights into the mechanisms of venous thrombosis. J Clin Invest 122:2331-2336.
http://www.ncbi.nlm.nih.gov/pubmed/22751108
Morrissey JH, Choi SH, Smith SA (2012) Polyphosphate: an ancient molecule that links platelets, coagulation, and inflammation. Blood 119:5972-5979.
http://www.ncbi.nlm.nih.gov/pubmed/22517894
Nielsen VG, Hafner DT (2012) Freezing does not decrease carbon monoxide-mediated hypercoagulation and hypofibrinolysis in human plasma. Blood Coagul Fibrinolysis.
http://www.ncbi.nlm.nih.gov/pubmed/22964769
Peng Y, Li Q, Zhang L, Bai M, Zhang Z (2012) Peroxisome Proliferator-Activated Receptor alpha Plays an Important Role in the Expression of Monocyte Chemoattractant Protein-1 and Neointimal Hyperplasia after Vascular Injury. PPAR Res 2012:970525.
http://www.ncbi.nlm.nih.gov/pubmed/22966226
Pugh N, Jarvis GE, Koch A, Sakariassen KS, Davis B, Farndale RW (2012) The impact of factor Xa inhibition on axial dependent arterial thrombus formation triggered by a tissue factor rich surface. J Thromb Thrombolysis 33:6-15.
http://www.ncbi.nlm.nih.gov/pubmed/22120925
Reid VL, Webster NR (2012) Role of microparticles in sepsis. Br J Anaesth 109:503-513.
http://www.ncbi.nlm.nih.gov/pubmed/22952169
Reimer J, Bien S, Ameling S, Hammer E, Volker U, Hempel G, . . . Ritter CA (2012) Antineoplastic agent busulfan regulates a network of genes related to coagulation and fibrinolysis. Eur J Clin Pharmacol 68:923-935.
http://www.ncbi.nlm.nih.gov/pubmed/22286157
Rossetto V, Spiezia L, Senzolo M, Rodriguez K, Gavasso S, Woodhams B, Simioni P (2012) Factor VIIa-antithrombin complexes in patients with non-neoplastic portal vein thrombosis with and without cirrhosis. Int J Lab Hematol.
http://www.ncbi.nlm.nih.gov/pubmed/22958499
Santos MJ, Carmona-Fernandes D, Canhao H, Canas da Silva J, Fonseca JE, Gil V (2012) Early Vascular Alterations in SLE and RA Patients-A Step towards Understanding the Associated Cardiovascular Risk. PLoS One 7:e44668.
http://www.ncbi.nlm.nih.gov/pubmed/22962622
Schindhelm RK, Wondergem MJ, Admiraal J, Nap G, Boekel ET, Hani L (2012) A patient with a prolonged activated partial thromboplastin time and a deep intracerebral haemorrhage. Case Rep Neurol 4:131-136.
http://www.ncbi.nlm.nih.gov/pubmed/22949911
Solvik UO, Roraas TH, Petersen PH, Stavelin AV, Monsen G, Sandberg S (2012) Effect of coagulation factors on discrepancies in International Normalized Ratio results between instruments. Clin Chem Lab Med 50:1611-1620.
http://www.ncbi.nlm.nih.gov/pubmed/22962222
Turfan M, Poyraz F, Ozturk Kaymak A, Ergun MA, Tavil Y, Gursel T, Abaci A (2012) Plasma Levels and Distribution of Gene Polymorphisms of Factor VII in Turkish Population. Clin Appl Thromb Hemost.
http://www.ncbi.nlm.nih.gov/pubmed/22964781
Wu D, Xiong L, Wu S, Jiang M, Lian G, Wang M (2012) TFPI-2 methylation predicts poor prognosis in non-small cell lung cancer. Lung Cancer 76:106-111.
http://www.ncbi.nlm.nih.gov/pubmed/21983100
Xie H, Zhou H, Wang H, Chen D, Xia L, Wang T, Yan J (2012) Anti-beta(2)GPI/beta(2)GPI induced TF and TNF-alpha expression in monocytes involving both TLR4/MyD88 and TLR4/TRIF signaling pathways. Mol Immunol 53:246-254.
http://www.ncbi.nlm.nih.gov/pubmed/22964479
Young G, Auerswald G, Jimenez-Yuste V, Lambert T, Morfini M, Santagostino E, Blanchette V (2012) PRO-PACT: Retrospective observational study on the prophylactic use of recombinant factor VIIa in hemophilia patients with inhibitors. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22964026
__________________________________________________________
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
__________________________________________________________