Vol. 23, No. 9

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 23, No. 9  May 1, 2017

(The next issue will be on May 15, 2017)

_________________________________

TRIGGER is also available by RSS Feed:

http://feeds.feedburner.com/blogspot/glro

and BLOG:
http://trigger-tf7.blogspot.com/
_________________________________

PAPERS IN PRESS

None submitted for this issue.

_________________________________
UPCOMING MEETINGS EVENTS

General info on upcoming meetings of interest:

http://tf7.org/meetings.htm

ISTH also maintains a list of upcoming meetings of interest:

https://www.isth.org/events/event_list.asp

_________________________________

RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI

Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.

THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":

https://www.ncbi.nlm.nih.gov/sites/myncbi/james.morrissey.1/collections/52521147/public/

Broussard J, Berlinger M, Lauret D (2017) A Clot (Possibly); Due to Loss of TNF-alpha Supression. J La State Med Soc 169:52.
http://www.ncbi.nlm.nih.gov/pubmed/28414674

Chen JJ, Wang AQ, Chen QQ (2017) DNA methylation assay for colorectal carcinoma. Cancer Biol Med 14:42-49.
http://www.ncbi.nlm.nih.gov/pubmed/28443202

Chitlur M, Rajpurkar M, Recht M, Tarantino MD, Yee DL, Cooper DL, Gunawardena S (2017) Recognition and management of platelet-refractory bleeding in patients with Glanzmann's thrombasthenia and other severe platelet function disorders. Int J Gen Med 10:95-99.
http://www.ncbi.nlm.nih.gov/pubmed/28435309

Christersson C, Thulin A, Siegbahn A (2017) Microparticles during long-term follow-up after acute myocardial infarction. Association to atherosclerotic burden and risk of cardiovascular events. Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/28424820

Cisowska-Czajka ME, Mazij MP, Kotschy MH, Lewczuk J (2016) Plasma concentrations of tissue factor and its inhibitor in chronic thromboembolic pulmonary hypertension: a step closer to explanation of the disease aetiology? Kardiol Pol 74:1332-1338.
http://www.ncbi.nlm.nih.gov/pubmed/27221958

Cosar H, Isik H, Cakir SC, Yar N, Goksen B, Tokbay H, . . . Durak I (2017) Recombinant Activated Factor VIIa (rFVIIa) Treatment in Very-Low-Birth-Weight (VLBW) Premature Infants with Acute Pulmonary Hemorrhage: A Single-Center, Retrospective Study. Paediatr Drugs 19:53-58.
http://www.ncbi.nlm.nih.gov/pubmed/27826851

Crispel Y, Ghanem S, Attias J, Kogan I, Brenner B, Nadir Y (2017) Involvement of heparanase procoagulant domain in bleeding and wound healing. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/28439967

da Silva GC, Abbas M, Khemais-Benkhiat S, Burban M, Ribeiro TP, Toti F, . . . Schini-Kerth VB (2017) Replicative senescence promotes prothrombotic responses in endothelial cells: Role of NADPH oxidase- and cyclooxygenase-derived oxidative stress. Exp Gerontol.
http://www.ncbi.nlm.nih.gov/pubmed/28412252

de Souza GR, Hounkpe BW, Fiusa MML, Colella MP, Annichino-Bizzacchi JM, Traina F, . . . De Paula EV (2017) Tissue factor-dependent coagulation activation by heme: A thromboelastometry study. PLoS One 12:e0176505.
http://www.ncbi.nlm.nih.gov/pubmed/28437457

Deng C, Wu S, Zhang L, Yang M, Lin Q, Xie Q, . . . Jin Y (2017) Role of monocyte tissue factor on patients with non-small cell lung cancer. Clin Respir J.
http://www.ncbi.nlm.nih.gov/pubmed/28419722

Dennis J, Medina-Rivera A, Truong V, Antounians L, Zwingerman N, Carrasco G, . . . Gagnon F (2017) Leveraging cell type specific regulatory regions to detect SNPs associated with tissue factor pathway inhibitor plasma levels. Genet Epidemiol.
http://www.ncbi.nlm.nih.gov/pubmed/28421636

Diamond SL (2016) Systems Analysis of Thrombus Formation. Circ Res 118:1348-1362.
http://www.ncbi.nlm.nih.gov/pubmed/27126646

Ding R, Zhao D, Li X, Liu B, Ma X (2017) Rho-kinase inhibitor treatment prevents pulmonary inflammation and coagulation in lipopolysaccharide-induced lung injury. Thromb Res 150:59-64.
http://www.ncbi.nlm.nih.gov/pubmed/28043040

Forier C, Boschetti E, Ouhammouch M, Cibiel A, Duconge F, Nogre M, . . . Perret G (2017) DNA aptamer affinity ligands for highly selective purification of human plasma-related proteins from multiple sources. J Chromatogr A 1489:39-50.
http://www.ncbi.nlm.nih.gov/pubmed/28179082

Gaitzsch E, Czermak T, Ribeiro A, Heun Y, Bohmer M, Merkle M, . . . Pircher J (2017) Double-stranded DNA induces a prothrombotic phenotype in the vascular endothelium. Sci Rep 7:1112.
http://www.ncbi.nlm.nih.gov/pubmed/28442771

Han X, Zha H, Yang F, Guo B, Zhu B (2017) Tumor-Derived Tissue Factor Aberrantly Activates Complement and Facilitates Lung Tumor Progression via Recruitment of Myeloid-Derived Suppressor Cells. Int J Mol Sci 18.
http://www.ncbi.nlm.nih.gov/pubmed/28106852

Hansson KM, Johansson KJ, Wingren C, Fries D, Nelander K, Lovgren A (2017) Recombinant human prothrombin reduced blood loss in a porcine model of dilutional coagulopathy with uncontrolled bleeding. Blood Coagul Fibrinolysis 28:244-253.
http://www.ncbi.nlm.nih.gov/pubmed/27428015

Hisada Y, Auriemma AC, Alexander W, Ay C, Mackman N (2017) Detection of tissue factor-positive extracellular vesicles by laser scanning confocal microscopy. Thromb Res 150:65-72.
http://www.ncbi.nlm.nih.gov/pubmed/28043041

Jahanban-Esfahlan R, Seidi K, Zarghami N (2017) Tumor vascular infarction: prospects and challenges. Int J Hematol 105:244-256.
http://www.ncbi.nlm.nih.gov/pubmed/28044258

Kavakli K, Demartis F, Karimi M, Eshghi P, Neme D, Chambost H, . . . Benson G (2017) Safety and effectiveness of room temperature stable recombinant factor VIIa in patients with haemophilia A or B and inhibitors: Results of a multinational, prospective, observational study. Haemophilia.
http://www.ncbi.nlm.nih.gov/pubmed/28440004

Koizume S, Miyagi Y (2017) Potential Coagulation Factor-Driven Pro-Inflammatory Responses in Ovarian Cancer Tissues Associated with Insufficient O(2) and Plasma Supply. Int J Mol Sci 18.
http://www.ncbi.nlm.nih.gov/pubmed/28417928

Lentz SR, Rangarajan S, Karim FA, Andersen PD, Arkhammar P, Rosu G, Mahlangu J (2017) The potential correlation between patient-reported symptoms and the use of additional haemostatic medication for joint bleeding in haemophilia patients with inhibitors: a post hoc exploratory analysis of recombinant activated factor VII data from the ADEPT2 trial. Blood Coagul Fibrinolysis 28:224-229.
http://www.ncbi.nlm.nih.gov/pubmed/27427786

Ogawa Y, Kunishima S, Yanagisawa K, Osaki Y, Uchiyama Y, Matsumoto N, . . . Handa H (2017) Successful management of perioperative hemostasis in a patient with Glanzmann thrombasthenia who underwent a right total mastectomy. Int J Hematol 105:221-225.
http://www.ncbi.nlm.nih.gov/pubmed/27696190

Quintavalle G, Riccardi F, Rivolta GF, Martorana D, Di Perna C, Percesepe A, Tagliaferri A (2017) F7 gene variants modulate protein levels in a large cohort of patients with factor VII deficiency. Results from a genotype-phenotype study. Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/28447100

Rocino A, Franchini M, Coppola A (2017) Treatment and Prevention of Bleeds in Haemophilia Patients with Inhibitors to Factor VIII/IX. J Clin Med 6.
http://www.ncbi.nlm.nih.gov/pubmed/28420167

Santamaria S, Reglinska-Matveyev N, Gierula M, Camire RM, Crawley JTB, Lane DA, Ahnstrom J (2017) Factor V anticoagulant cofactor activity that targets the early phase of coagulation. J Biol Chem.
http://www.ncbi.nlm.nih.gov/pubmed/28420729

Skowerski T, Banska-Kisiel K, Grzywocz P, Skowerski M, Gasior Z (2017) Pulmonary embolism in a patient with mild factor VII deficiency after administration of recombinant activated factor VII during a urological procedure. Pol Arch Intern Med 127:285-286.
http://www.ncbi.nlm.nih.gov/pubmed/28452972

Swier N, Versteeg HH (2017) Reciprocal links between venous thromboembolism, coagulation factors and ovarian cancer progression. Thromb Res 150:8-18.
http://www.ncbi.nlm.nih.gov/pubmed/27988375

Takeda S, Takeda J, Murakami K, Kubo T, Hamada H, Murakami M, . . . Ikeda T (2017) Annual Report of the Perinatology Committee, Japan Society of Obstetrics and Gynecology, 2015: Proposal of urgent measures to reduce maternal deaths. J Obstet Gynaecol Res 43:5-7.
http://www.ncbi.nlm.nih.gov/pubmed/28074548

Tang M, Fenger-Eriksen C, Wierup P, Greisen J, Ingerslev J, Hjortdal V, Sorensen B (2017) Rational and timely haemostatic interventions following cardiac surgery - coagulation factor concentrates or blood bank products. Thromb Res 154:73-79.
http://www.ncbi.nlm.nih.gov/pubmed/28437748

Tischer S, Miller JT (2016) Pharmacologic Strategies to Prevent Blood Loss and Transfusion in Orthotopic Liver Transplantation. Crit Care Nurs Q 39:267-280.
http://www.ncbi.nlm.nih.gov/pubmed/27254642

Tsunaka M, Shinki H, Koyama T (2017) Cell-based evaluation of changes in coagulation activity induced by antineoplastic drugs for the treatment of acute myeloid leukemia. PLoS One 12:e0175765.
http://www.ncbi.nlm.nih.gov/pubmed/28406995

Wang CY, Chen YC, Lin CH, Hwang KS, Su HY (2016) Successful treatment with recombinant blood factor VIIa in severe postpartum hemorrhage-induced disseminated intravascular coagulation. Taiwan J Obstet Gynecol 55:301-302.
http://www.ncbi.nlm.nih.gov/pubmed/27125421

Wool GD, Chapel D, Treml A, Miller JL (2017) Therapeutic plasma exchange as part of multimodal treatment of acquired hemophilia in a patient with concurrent acute intracerebral bleed and pulmonary embolism. Transfusion.
http://www.ncbi.nlm.nih.gov/pubmed/28436106

Xiao X, Tao X, Wang Y, Zhu L, Ye Y, Liu H, . . . Xiong Y (2017) Hypomethylation of tissue factor pathway inhibitor 2 in human placenta of preeclampsia. Thromb Res 152:7-13.
http://www.ncbi.nlm.nih.gov/pubmed/28208084

Yisireyili M, Hayashi M, Wu H, Uchida Y, Yamamoto K, Kikuchi R, . . . Takeshita K (2017) Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice. Sci Rep 7:1266.
http://www.ncbi.nlm.nih.gov/pubmed/28455534

_________________________________

ABOUT TRIGGER

TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.

DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
_________________________________

Vol. 23, No. 8

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 23, No. 8  April 17, 2017

(The next issue will be on May 1, 2017)

_________________________________

TRIGGER is also available by RSS Feed:

http://feeds.feedburner.com/blogspot/glro

and BLOG:
http://trigger-tf7.blogspot.com/
_________________________________

PAPERS IN PRESS

None submitted for this issue.

_________________________________
UPCOMING MEETINGS EVENTS

General info on upcoming meetings of interest:

http://tf7.org/meetings.htm

ISTH also maintains a list of upcoming meetings of interest:

https://www.isth.org/events/event_list.asp

_________________________________

RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI

Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.

THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":

https://www.ncbi.nlm.nih.gov/sites/myncbi/james.morrissey.1/collections/52440075/public/

Andreasen EB, Nielsen OL, Tranholm M, Knudsen T, Kristensen AT (2016) Expression of tissue factor in canine mammary tumours and correlation with grade, stage and markers of haemostasis and inflammation. Vet Comp Oncol 14:191-201.

http://www.ncbi.nlm.nih.gov/pubmed/24674618

Balasenthil S, Huang Y, Liu S, Marsh T, Chen J, Stass SA, . . . McNeill Killary A (2017) A Plasma Biomarker Panel to Identify Surgically Resectable Early-Stage Pancreatic Cancer. J Natl Cancer Inst 109.

http://www.ncbi.nlm.nih.gov/pubmed/28376184

Bode MF, Mackman N (2016) A combined deficiency of tissue factor and PAR-4 is associated with fatal pulmonary hemorrhage in mice. Thromb Res 146:46-50.

http://www.ncbi.nlm.nih.gov/pubmed/27586081

Chiva-Blanch G, Suades R, Padro T, Vilahur G, Pena E, Ybarra J, . . . Badimon L (2016) Microparticle Shedding by Erythrocytes, Monocytes and Vascular Smooth Muscular Cells Is Reduced by Aspirin in Diabetic Patients. Rev Esp Cardiol (Engl Ed) 69:672-680.

http://www.ncbi.nlm.nih.gov/pubmed/27103451

Christy BA, Herzig MC, Montgomery RK, Delavan C, Bynum JA, Reddoch KM, Cap AP (2017) Pro-coagulant activity of human mesenchymal stem cells. J Trauma Acute Care Surg.

http://www.ncbi.nlm.nih.gov/pubmed/28383473

Claussen C, Rausch AV, Lezius S, Amirkhosravi A, Davila M, Francis JL, . . . Langer F (2016) Microvesicle-associated tissue factor procoagulant activity for the preoperative diagnosis of ovarian cancer. Thromb Res 141:39-48.

http://www.ncbi.nlm.nih.gov/pubmed/26967531

Dager WE, Banares L (2017) Reversing the anticoagulation effects of dabigatran. Hosp Pract (1995) 45:29-38.

http://www.ncbi.nlm.nih.gov/pubmed/28335637

Enjeti AK, Ariyarajah A, D'Crus A, Seldon M, Lincz LF (2016) Correlative analysis of nanoparticle tracking, flow cytometric and functional measurements for circulating microvesicles in normal subjects. Thromb Res 145:18-23.

http://www.ncbi.nlm.nih.gov/pubmed/27429418

Gao F, Wang FG, Liu RR, Xue F, Zhang J, Xu GQ, . . . Huo R (2017) Epigenetic silencing of miR-130a ameliorates hemangioma by targeting tissue factor pathway inhibitor 2 through FAK/PI3K/Rac1/mdm2 signaling. Int J Oncol 50:1821-1831.

http://www.ncbi.nlm.nih.gov/pubmed/28393235

Gheldof D, Haguet H, Dogne JM, Bouvy C, Graux C, George F, . . .

Mullier F (2017) Procoagulant activity of extracellular vesicles as a potential biomarker for risk of thrombosis and DIC in patients with acute leukaemia. J Thromb Thrombolysis 43:224-232.

http://www.ncbi.nlm.nih.gov/pubmed/28074413

Gocmen G, Aktop S, Tuzuner B, Goker B, Yarat A (2017) Effects of hyaluronic acid on bleeding following third molar extraction. J Appl Oral Sci 25:211-216.

http://www.ncbi.nlm.nih.gov/pubmed/28403362

Guzzetta NA, Williams GD (2017) Current use of factor concentrates in pediatric cardiac anesthesia. Paediatr Anaesth.

http://www.ncbi.nlm.nih.gov/pubmed/28393462

Huang B, Park DW, Baek SH (2016) TRIF is a regulator of TLR2-induced foam cell formation. Mol Med Rep 14:3329-3335.

http://www.ncbi.nlm.nih.gov/pubmed/27572666

Jung SH, Hwang JH, Kim SE, Young Kyu K, Park HC, Lee HT (2017) The potentiating effect of hTFPI in the presence of hCD47 reduces the cytotoxicity of human macrophages. Xenotransplantation.

http://www.ncbi.nlm.nih.gov/pubmed/28393401

Lakbakbi S, Debrumetz A, Terryn C, Szymezak J, Rieu P, Nguyen P (2016) Tissue factor expressed by adherent cells contributes to hemodialysis-membrane thrombogenicity. Thromb Res 144:218-223.

http://www.ncbi.nlm.nih.gov/pubmed/27423005

Levi M, van der Poll T (2017) Coagulation and sepsis. Thromb Res 149:38-44.

http://www.ncbi.nlm.nih.gov/pubmed/27886531

Li W, Chen W, Xie M, Huang H, Su H, Han H, . . . Wei J (2016) Fasudil inhibits tissue factor and plasminogen activator Inhibitor-1 secretion by peripheral blood mononuclear cells in CAPD patients. Ren Fail 38:1359-1363.

http://www.ncbi.nlm.nih.gov/pubmed/27756191

Matsunari Y, Sugimoto M, Doi M, Matsui H, Kawaguchi M (2016) Functional characterization of tissue factor in von Willebrand factor-dependent thrombus formation under whole blood flow conditions. Int J Hematol 104:661-668.

http://www.ncbi.nlm.nih.gov/pubmed/27562418

Narita I, Shimada M, Yamabe H, Kinjo T, Tanno T, Nishizaki K, . . . Okumura K (2016) NF-kappaB-dependent increase in tissue factor expression is responsible for hypoxic podocyte injury. Clin Exp Nephrol 20:679-688.

http://www.ncbi.nlm.nih.gov/pubmed/26715508

Nishiura N, Ujimoto D, Fujita J, Maeda T, Nakagawa Y, Kashiwagi H, . . . Kanakura Y (2017) Autoimmune bullous disease and Hashimoto's disease complicated by acquired hemophilia A. Rinsho Ketsueki 58:233-238.

http://www.ncbi.nlm.nih.gov/pubmed/28381691

Otomo K, Amengual O, Fujieda Y, Nakagawa H, Kato M, Oku K, . . . Atsumi T (2016) Role of apolipoprotein B100 and oxidized low-density lipoprotein in the monocyte tissue factor induction mediated by anti-beta2 glycoprotein I antibodies. Lupus 25:1288-1298.

http://www.ncbi.nlm.nih.gov/pubmed/26964561

Oztay F, Kara-Kisla B, Orhan N, Yanardag R, Bolkent S (2016) The protective effects of prostaglandin E1 on lung injury following renal ischemia-reperfusion in rats. Toxicol Ind Health 32:1684-1692.

http://www.ncbi.nlm.nih.gov/pubmed/25883098

Pfeiffer C, Mathieu-Dupas E, Logghe P, Lissalde-Lavigne G, Balicchi J, Caliskan U, . . . Giansily-Blaizot M (2016) Isotypic analysis of antibodies against activated Factor VII in patients with Factor VII deficiency using the x-MAP technology. Thromb Res 141:22-27.

http://www.ncbi.nlm.nih.gov/pubmed/26962982

Recht M, Rajpurkar M, Chitlur M, d'Oiron R, Zotz R, Di Minno G, . . . Poon MC (2017) Independent Adjudicator Assessments of Platelet Refractoriness and rFVIIa Efficacy in Bleeding Episodes and Surgeries from the Multinational Glanzmann's Thrombasthenia Registry. Am J Hematol.

http://www.ncbi.nlm.nih.gov/pubmed/28370369

Reddy M, Tawfik B, Gavva C, Yates S, De Simone N, Hofmann SL, . . . Sarode R (2016) Ischemic stroke in a patient with moderate to severe inherited factor VII deficiency. Transfus Apher Sci 55:364-367.

http://www.ncbi.nlm.nih.gov/pubmed/27776919

Shang J, Yamashita T, Kono S, Morihara R, Nakano Y, Fukui Y, . . . Abe K (2016) Effects of Pretreatment with Warfarin or Rivaroxaban on Neurovascular Unit Dissociation after Tissue Plasminogen Activator Thrombolysis in Ischemic Rat Brain. J Stroke Cerebrovasc Dis 25:1997-2003.

http://www.ncbi.nlm.nih.gov/pubmed/27230587

Staibano P, Arnold DM, Bowdish DM, Nazy I (2017) The unique immunological features of heparin-induced thrombocytopenia. Br J Haematol 177:198-207.

http://www.ncbi.nlm.nih.gov/pubmed/28369702

Tandale SR, Khedkar SM, Yadav AH, Ajatshatru S (2017) Congenital factor VII deficiency: Multidisciplinary approach is the key to successful perioperative outcome. Indian J Anaesth 61:275-276.

http://www.ncbi.nlm.nih.gov/pubmed/28405048

Tinholt M, Sandset PM, Mowinckel MC, Garred O, Sahlberg KK, Kristensen VN, . . . Iversen N (2016) Determinants of acquired activated protein C resistance and D-dimer in breast cancer. Thromb Res 145:78-83.

http://www.ncbi.nlm.nih.gov/pubmed/27505249

Tsunaka M, Shinki H, Koyama T (2017) Cell-based evaluation of changes in coagulation activity induced by antineoplastic drugs for the treatment of acute myeloid leukemia. PLoS One 12:e0175765.

http://www.ncbi.nlm.nih.gov/pubmed/28406995

Yang M, Deng C, Wu D, Zhong Z, Lv X, Huang Z, . . . Zhang Q (2016) The role of mononuclear cell tissue factor and inflammatory cytokines in patients with chronic thromboembolic pulmonary hypertension. J Thromb Thrombolysis 42:38-45.

http://www.ncbi.nlm.nih.gov/pubmed/26667361

Yau JW, Singh KK, Hou Y, Lei X, Ramadan A, Quan A, . . . Verma S (2017) Endothelial-specific deletion of autophagy-related 7 (ATG7) attenuates arterial thrombosis in mice. J Thorac Cardiovasc Surg.

http://www.ncbi.nlm.nih.gov/pubmed/28400112

_________________________________

ABOUT TRIGGER

TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.

DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
_________________________________