TRIGGER current issue: 2011

Thursday, December 15, 2011

Vol. 17, No. 24

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 24 December 15, 2011

(The next issue will be on January 2, 2012)

__________________________________________________________
TRIGGER is also available by RSS Feed:

http://feeds.feedburner.com/blogspot/glro

and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________
ANNOUNCEMENTS
Our best holiday wishes to all the TRIGGER subscribers for a happy, healthy and prosperous New Year!

-Jim & Genie Morrissey and Pierre Neuenschwander
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PAPERS IN PRESS
None submitted for this issue.
__________________________________________________________
UPCOMING MEETINGS & EVENTS
The meeting brochure and online registration for the upcoming "6th Symposium on Hemostasis with Special Focus on Tissue Factor, Factor VIIa and Tissue Factor Pathway Inhibitor-- Hemostasis and Beyond" are now available at:
http://medicine.med.unc.edu/hemonc/tf2012
The meeting will be held on 3-5 May 2012, at the Carolina Inn, Chapel Hill NC, USA.
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RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI

Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.

THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1jme8kBYm8u5kkri2b58UN-/

Binny C, McIntosh J, Della Peruta M, Kymalainen H, Tuddenham EG, Buckley SM, . . . Nathwani AC (2011) AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous haemorrhage. Blood.
http://www.ncbi.nlm.nih.gov/pubmed/22134170

Brophy DF, Martin EJ, Barrett JC, Nolte ME, Kuhn JG, Hedner U, Ezban M (2011) Overcoming delayed in-vitro response to rFVIIa: effects of rFVIIa and rFVIIa analogue (vatreptacog alfa) concentration escalation in whole blood assays. Blood Coagul Fibrinolysis 22:541-546.
http://www.ncbi.nlm.nih.gov/pubmed/21681082

Brophy DF, Martin EJ, Christian Barrett J, Nolte ME, Kuhn JG, Gerk PM, . . . Hedner U (2011) Monitoring rFVIIa 90 mug kg(1) dosing in haemophiliacs: comparing laboratory response using various whole blood assays over 6 h. Haemophilia 17:e949-957.
http://www.ncbi.nlm.nih.gov/pubmed/21362113

Camire RM (2011) A new look at blood coagulation factor V. Curr Opin Hematol 18:338-342.
http://www.ncbi.nlm.nih.gov/pubmed/21730834

Carlsson K, Persson E, Lindgren M, Carlsson U, Svensson M (2011) Effects on the conformation of FVIIa by sTF and Ca(2) binding: studies of fluorescence resonance energy transfer and quenching. Biochem Biophys Res Commun 413:545-549.
http://www.ncbi.nlm.nih.gov/pubmed/21924243

Chavez-Tapia NC, Alfaro-Lara R, Tellez-Avila F, Barrientos-Gutierrez T, Gonzalez-Chon O, Mendez-Sanchez N, Uribe M (2011) Prophylactic activated recombinant factor VII in liver resection and liver transplantation: systematic review and meta-analysis. PLoS One 6:e22581.
http://www.ncbi.nlm.nih.gov/pubmed/21818342

Cocco E, Varughese J, Buza N, Bellone S, Lin KY, Bellone M, . . . Santin AD (2011) Tissue factor expression in ovarian cancer: implications for immunotherapy with hI-con1, a factor VII-IgGF(c) chimeric protein targeting tissue factor. Clin Exp Metastasis 28:689-700.
http://www.ncbi.nlm.nih.gov/pubmed/21725665

Collins PW (2011) Management of acquired haemophilia A. J Thromb Haemost 9 Suppl 1:226-235.
http://www.ncbi.nlm.nih.gov/pubmed/21781259

Cui MZ (2011) Lysophosphatidic acid effects on atherosclerosis and thrombosis. Clin Lipidol 6:413-426.
http://www.ncbi.nlm.nih.gov/pubmed/22162980

Egorina EM, Sovershaev MA, Hansen JB (2011) The role of tissue factor in systemic inflammatory response syndrome. Blood Coagul Fibrinolysis 22:451-456.
http://www.ncbi.nlm.nih.gov/pubmed/21597365

Esmon CT, Xu J, Lupu F (2011) Innate immunity and coagulation. J Thromb Haemost 9 Suppl 1:182-188.
http://www.ncbi.nlm.nih.gov/pubmed/21781254

Girard TJ, Tuley E, Broze GJ, Jr. (2011) TFPIbeta is the GPI-anchored TFPI isoform on human endothelial cells and placental microsomes. Blood.
http://www.ncbi.nlm.nih.gov/pubmed/22144186

Gurusamy KS, Pissanou T, Pikhart H, Vaughan J, Burroughs AK, Davidson BR (2011) Methods to decrease blood loss and transfusion requirements for liver transplantation. Cochrane Database Syst Rev 12:CD009052.
http://www.ncbi.nlm.nih.gov/pubmed/22161443

Hay JW, Zhou ZY (2011) Economical comparison of APCC vs. rFVIIa for mild-to-moderate bleeding episodes in haemophilia patients with inhibitors. Haemophilia 17:e969-974.
http://www.ncbi.nlm.nih.gov/pubmed/21649802

Hibi K, Goto T, Shirahata A, Saito M, Kigawa G, Nemoto H, Sanada Y (2011) Detection of TFPI2 methylation in the serum of colorectal cancer patients. Cancer Lett 311:96-100.
http://www.ncbi.nlm.nih.gov/pubmed/21820798

Hoshi A, Matsumoto A, Chung J, Isozumi Y, Koyama T (2011) Activation of coagulation by a thalidomide-based regimen. Blood Coagul Fibrinolysis 22:532-540.
http://www.ncbi.nlm.nih.gov/pubmed/21670663

Hwang SM, Kim JE, Han KS, Kim HK (2011) Thrombomodulin phenotype of a distinct monocyte subtype is an independent prognostic marker for disseminated intravascular coagulation. Crit Care 15:R113.
http://www.ncbi.nlm.nih.gov/pubmed/21489300

Ingerslev J, Sorensen B (2011) Parallel use of by-passing agents in haemophilia with inhibitors: a critical review. Br J Haematol 155:256-262.
http://www.ncbi.nlm.nih.gov/pubmed/21895627

Kakko T, Jaakkola U, Raitakari OT, Kallio J (2011) Inflammatory effects of blood leukocytes: association with vascular function in neuropeptide Y proline 7-genotyped type 2 diabetes patients. Diab Vasc Dis Res 8:221-228.
http://www.ncbi.nlm.nih.gov/pubmed/21746772

Kayem G, Kurinczuk JJ, Alfirevic Z, Spark P, Brocklehurst P, Knight M (2011) Specific second-line therapies for postpartum haemorrhage: a national cohort study. BJOG 118:856-864.
http://www.ncbi.nlm.nih.gov/pubmed/21392247

Kim WJ, Oh JY, Son HJ, Chin JH, Choi DK, Lee EH, . . . Choi IC (2011) The prophylactic use of recombinant factor VIIa in a patient with DeBakey type III aortic dissection -A case report. Korean J Anesthesiol 61:431-434.
http://www.ncbi.nlm.nih.gov/pubmed/22148094

Knudsen T, Kjalke M, Tranholm M, Nichols TC, Jensen AL, Kristensen AT (2011) Development of a flow cytometric assay for detection of coated platelets in dogs and evaluation of binding of coated platelets to recombinant human coagulation factor VIIa. Am J Vet Res 72:1007-1014.
http://www.ncbi.nlm.nih.gov/pubmed/21801056

Kobayashi T, Nakabayashi M, Yoshioka A, Maeda M, Ikenoue T (2011) Recombinant activated factor VII (rFVIIa/NovoSeven((R))) in the management of severe postpartum haemorrhage: initial report of a multicentre case series in Japan. Int J Hematol.
http://www.ncbi.nlm.nih.gov/pubmed/22160834

Krijnen PA, Hahn NE, Kholova I, Baylan U, Sipkens JA, van Alphen FP, . . . Niessen HW (2012) Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients. Basic Res Cardiol 107:1-13.
http://www.ncbi.nlm.nih.gov/pubmed/22167343

Kruthika-Vinod TP, Nagaraja D, Christopher R (2011) Coagulation factor VII R353Q polymorphism and the risk of puerperal cerebral venous thrombosis. J Clin Neurosci.
http://www.ncbi.nlm.nih.gov/pubmed/22136731

Krysiak R, Gdula-Dymek A, Okopien B (2011) Hemostatic effects of bezafibrate and omega-3 fatty acids in isolated hypertriglyceridemic patients. Pharmacol Rep 63:763-771.
http://www.ncbi.nlm.nih.gov/pubmed/21857087

Latchamsetty R, Gautam S, Bhakta D, Chugh A, John RM, Epstein LM, . . . Jongnarangsin K (2011) Management and outcomes of cardiac tamponade during atrial fibrillation ablation in the presence of therapeutic anticoagulation with warfarin. Heart Rhythm 8:805-808.
http://www.ncbi.nlm.nih.gov/pubmed/21236362

Lemon SJ, Jr., Crannage AJ (2011) Pharmacologic anticoagulation reversal in the emergency department. Adv Emerg Nurs J 33:212-223; quiz 224-215.
http://www.ncbi.nlm.nih.gov/pubmed/21836448

Li J, Liu Y, Yin W, Zhang C, Huang J, Liao C, . . . Xiao P (2011) Alterations of the preoperative coagulation profile in patients with acute appendicitis. Clin Chem Lab Med 49:1333-1339.
http://www.ncbi.nlm.nih.gov/pubmed/21663567

Lisman T, Porte RJ (2011) Recombinant factor VIIa to treat severe bleeding in patients with liver disease: pitfalls and possibilities. J Hepatol 55:950-951.
http://www.ncbi.nlm.nih.gov/pubmed/21925325

Liu Y, Jiang P, Capkova K, Xue D, Ye L, Sinha SC, . . . Liu C (2011) Tissue factor-activated coagulation cascade in the tumor microenvironment is critical for tumor progression and an effective target for therapy. Cancer Res 71:6492-6502.
http://www.ncbi.nlm.nih.gov/pubmed/21880589

Luszczak J, Undas A, Gissel M, Olszowska M, Butenas S (2011) Activated factor XI and tissue factor in aortic stenosis: links with thrombin generation. Blood Coagul Fibrinolysis 22:473-479.
http://www.ncbi.nlm.nih.gov/pubmed/21519234

Mayne E, Funderburg NT, Sieg SF, Asaad R, Kalinowska M, Rodriguez B, . . . Lederman MM (2011) Increased platelet and microparticle activation in HIV infection: upregulation of P-selectin and tissue factor expression. J Acquir Immune Defic Syndr.
http://www.ncbi.nlm.nih.gov/pubmed/22156911

Meisel SR, Xu XP, Edgington TS, Cercek B, Ong J, Kaul S, Shah PK (2011) Dose-dependent modulation of tissue factor protein and procoagulant activity in human monocyte-derived macrophages by oxidized low density lipoprotein. J Atheroscler Thromb 18:596-603.
http://www.ncbi.nlm.nih.gov/pubmed/21467727

Milligan C, Higginson I, Smith JE (2011) Emergency department staff knowledge of massive transfusion for trauma: the need for an evidence based protocol. Emerg Med J 28:870-872.
http://www.ncbi.nlm.nih.gov/pubmed/21030544

Paluszkiewicz P, Mayzner-Zawadzka E, Baranowski W, Breborowicz GH, Brzezinski M, Durek G, . . . Wujtewicz M (2011) Recommendations for the management of trauma or surgery-related massive blood loss. Pol Przegl Chir 83:465-476.
http://www.ncbi.nlm.nih.gov/pubmed/22166722

Park JB, Kim BK, Kwon YW, Muller DN, Lee HC, Youn SW, . . . Kim HS (2011) Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with Paclitaxel infusion. PLoS One 6:e28327.
http://www.ncbi.nlm.nih.gov/pubmed/22140576

Patanwala AE, Acquisto NM, Erstad BL (2011) Prothrombin complex concentrate for critical bleeding. Ann Pharmacother 45:990-999.
http://www.ncbi.nlm.nih.gov/pubmed/21730276

Peled E, Rovitsky A, Axelman E, Norman D, Brenner B, Nadir Y (2011) Increased heparanase level and procoagulant activity in orthopedic surgery patients receiving prophylactic dose of enoxaparin. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22154361

Quezada M, Diaz J, Henriquez S, Bravo ML, Aranda E, Oliva B, . . . Owen GI (2010) 2-Methoxyestradiol inhibits progesterone-dependent tissue factor expression and activity in breast cancer cells. Horm Cancer 1:117-126.
http://www.ncbi.nlm.nih.gov/pubmed/21761355

Rasekh HR, Imani A, Karimi M, Golestani M (2011) Cost-utility analysis of immune tolerance induction therapy versus on-demand treatment with recombinant factor VII for hemophilia A with high titer inhibitors in Iran. Clinicoecon Outcomes Res 3:207-212.
http://www.ncbi.nlm.nih.gov/pubmed/22163168

Ruf W, Disse J, Carneiro-Lobo TC, Yokota N, Schaffner F (2011) Tissue factor and cell signalling in cancer progression and thrombosis. J Thromb Haemost 9 Suppl 1:306-315.
http://www.ncbi.nlm.nih.gov/pubmed/21781267

Saito Y, Hashimoto Y, Kuroda J, Yasunaga M, Koga Y, Takahashi A, Matsumura Y (2011) The inhibition of pancreatic cancer invasion-metastasis cascade in both cellular signal and blood coagulation cascade of tissue factor by its neutralisation antibody. Eur J Cancer 47:2230-2239.
http://www.ncbi.nlm.nih.gov/pubmed/21621407

Sangha N, Gonzales NR (2011) Treatment targets in intracerebral hemorrhage. Neurotherapeutics 8:374-387.
http://www.ncbi.nlm.nih.gov/pubmed/21732225

Sartori MT, Della Puppa A, Ballin A, Saggiorato G, Bernardi D, Padoan A, . . . Cella G (2011) Prothrombotic state in glioblastoma multiforme: an evaluation of the procoagulant activity of circulating microparticles. J Neurooncol 104:225-231.
http://www.ncbi.nlm.nih.gov/pubmed/21104297

Schmid D, Svoboda M, Sorgner A, Moravcevic I, Thalhammer T, Chiba P, Moslinger T (2011) Glibenclamide reduces proinflammatory cytokines in an ex vivo model of human endotoxinaemia under hypoxaemic conditions. Life Sci 89:725-734.
http://www.ncbi.nlm.nih.gov/pubmed/21925514

Schmid P, Mordasini A, Luginbuhl M, Regli B, Kohler HP, Zimmermann H, . . . Alberio L (2011) Low-dose recombinant factor VIIa for massive bleeding: a single centre observational cohort study with 73 patients. Swiss Med Wkly 141:w13213.
http://www.ncbi.nlm.nih.gov/pubmed/21735365

Shander A, Walsh CE, Cromwell C (2011) Acquired hemophilia: a rare but life-threatening potential cause of bleeding in the intensive care unit. Intensive Care Med 37:1240-1249.
http://www.ncbi.nlm.nih.gov/pubmed/21626430

Siddiq S, Clark A, Mumford A (2011) A systematic review of the management and outcomes of pregnancy in Glanzmann thrombasthenia. Haemophilia 17:e858-869.
http://www.ncbi.nlm.nih.gov/pubmed/21457404

Sie P, Samama CM, Godier A, Rosencher N, Steib A, Llau JV, . . . Albaladejo P (2011) Surgery and invasive procedures in patients on long-term treatment with direct oral anticoagulants: Thrombin or factor-Xa inhibitors. Recommendations of the Working Group on perioperative haemostasis and the French Study Group on thrombosis and haemostasis. Arch Cardiovasc Dis 104:669-676.
http://www.ncbi.nlm.nih.gov/pubmed/22152517

Sorour Y, Van Veen JJ, Makris M (2010) Recombinant factor VIIa for unlicensed indications--a definite No or a cautious Maybe in selected patients? Int J Clin Pract 64:1468-1471.
http://www.ncbi.nlm.nih.gov/pubmed/20722768

Stephan F, Hazelzet JA, Bulder I, Boermeester MA, van Till JO, van der Poll T, . . . Zeerleder S (2011) Activation of factor VII-activating protease in human inflammation: a sensor for cell death. Crit Care 15:R110.
http://www.ncbi.nlm.nih.gov/pubmed/21466697

Stokol T, Daddona JL, Mubayed LS, Trimpert J, Kang S (2011) Evaluation of tissue factor expression in canine tumor cells. Am J Vet Res 72:1097-1106.
http://www.ncbi.nlm.nih.gov/pubmed/21801068

Storgaard M, Henriksen ST, Zaragoza F, Peschke B, Tanner D (2011) Design, synthesis and biological activity of novel peptidyl benzyl ketone FVIIa inhibitors. Bioorg Med Chem Lett 21:3918-3922.
http://www.ncbi.nlm.nih.gov/pubmed/21641796

Takeuchi H, Fernandez-Valdivia RC, Caswell DS, Nita-Lazar A, Rana NA, Garner TP, . . . Haltiwanger RS (2011) Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase. Proc Natl Acad Sci U S A 108:16600-16605.
http://www.ncbi.nlm.nih.gov/pubmed/21949356

Tang JQ, Fan Q, Wu WH, Jia ZC, Li H, Yang YM, . . . Wan YL (2010) Extrahepatic synthesis of coagulation factor VII by colorectal cancer cells promotes tumor invasion and metastasis. Chin Med J (Engl) 123:3559-3565.
http://www.ncbi.nlm.nih.gov/pubmed/22166631

Tran HT, Tjonnfjord GE, Paus A, Holme PA (2011) rFVIIa administered by continuous infusion during surgery in patients with severe congenital FVII deficiency. Haemophilia 17:764-770.
http://www.ncbi.nlm.nih.gov/pubmed/21707871

van den Hengel LG, Kocaturk B, Reitsma PH, Ruf W, Versteeg HH (2011) Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor. Blood 118:3446-3448.
http://www.ncbi.nlm.nih.gov/pubmed/21940832

Vang ML, Hvas AM, Ravn HB (2011) Urgent reversal of vitamin K antagonist therapy. Acta Anaesthesiol Scand 55:507-516.
http://www.ncbi.nlm.nih.gov/pubmed/21418150

Versteeg HH, Ruf W (2011) Thiol pathways in the regulation of tissue factor prothrombotic activity. Curr Opin Hematol 18:343-348.
http://www.ncbi.nlm.nih.gov/pubmed/21778880

Walsh M, Thomas SG, Howard JC, Evans E, Guyer K, Medvecz A, . . . Castellino FJ (2011) Blood component therapy in trauma guided with the utilization of the perfusionist and thromboelastography. J Extra Corpor Technol 43:162-167.
http://www.ncbi.nlm.nih.gov/pubmed/22164456

Weatherall J, Barnes N, Brown C, Preaud E (2011) Future characteristics of bypassing agents to improve care of hemophilia inhibitor patients: an economic and health-related quality of life perspective. Expert Rev Pharmacoecon Outcomes Res 11:411-414.
http://www.ncbi.nlm.nih.gov/pubmed/21831021

Wyckoff T, Reed EA, Desai ND, Augoustides JG (2011) Possible Anaphylaxis Due to Recombinant Factor VIIa Administration During Thoracic Aortic Surgery. J Cardiothorac Vasc Anesth.
http://www.ncbi.nlm.nih.gov/pubmed/22155168

Yamamoto E, Nishimura N, Okada K, Sekido C, Yamamichi S, Hasumi K (2011) Inhibitors of autoactivation of plasma hyaluronan-binding protein (factor VII activating protease). Biol Pharm Bull 34:462-470.
http://www.ncbi.nlm.nih.gov/pubmed/21467630

Young G, Auerswald G, Jimenez-Yuste V, Konkle BA, Lambert T, Morfini M, . . . Blanchette V (2011) When should prophylaxis therapy in inhibitor patients be considered? Haemophilia 17:e849-857.
http://www.ncbi.nlm.nih.gov/pubmed/21418444

Zhu J, Xie R, Piao X, Hou Y, Zhao C, Qiao G, . . . Lu Y (2011) Homocysteine enhances clot-promoting activity of endothelial cells via phosphatidylserine externalization and microparticles formation. Amino Acids.
http://www.ncbi.nlm.nih.gov/pubmed/22160264
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ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.

DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
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Monday, December 12, 2011

Vol. 17, No. 23

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 23 December 1, 2011

(The next issue will be on December 15, 2011)

__________________________________________________________
TRIGGER is also available by RSS Feed:

http://feeds.feedburner.com/blogspot/glro

and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________

POSITIONS SOUGHT/AVAILABLE
The UNC McAllister Heart Institute, in collaboration with the departments in the School of Medicine and across the entire University, seeks outstanding candidates for an open-rank position at all levels of basic/translational research. This recruitment seeks a research scientist/physician interested in cardiovascular disease, including but not limited to vascular development, angiogenesis, cardiac pathology, and thrombosis. Applicants should have a strong record of recent accomplishments as a post-doctoral fellow or sustained productivity as an established faculty member. Academic credentials and experience will determine rank, track, and salary in an appropriate academic department. Applications will be reviewed beginning November 10, 2011 and until the position is filled.

Applicants must submit a letter of interest, curriculum vitae, a description of research plans, and names of four references through UNC Chapel Hill's web-based system. PDF documents are preferred. The following link will direct you to the position:
http://jobs.unc.edu/2502018

UNC McAllister Heart Institute and the University of North Carolina is an Equal Opportunity Employer. Hiring is contingent upon eligibility to work in the United States. Women and minorities are encouraged to apply.
__________________________________________________________
PAPERS IN PRESS

None submitted for this issue.
__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI

THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1felWqyBWcGWhnjhWiipypk/

Alstrom U, Levin LA, Stahle E, Svedjeholm R, Friberg O (2011) Cost analysis of re-exploration for bleeding after coronary artery bypass graft surgery. Br J Anaesth.
http://www.ncbi.nlm.nih.gov/pubmed/22113929

Bhananker SM, Ramaiah R (2011) Trends in trauma transfusion. Int J Crit Illn Inj Sci 1:51-56.
http://www.ncbi.nlm.nih.gov/pubmed/22096774

Bouchama A, Al-Mohanna F, Assad L, Baturcam E, Eldali A, Owaidah T, Dehbi M (2011) Tissue factor/factor VIIa pathway mediates coagulation activation in induced-heat stroke in the baboon. Crit Care Med.
http://www.ncbi.nlm.nih.gov/pubmed/22080642

Busch JD, Van Andel R, Cordova J, Colman RE, Keim P, Rocke TE, . . . Wagner DM (2011) Population Differences in Host Immune Factors May Influence Survival of Gunnison's Prairie Dogs (Cynomys gunnisoni) during Plague Outbreaks. J Wildl Dis 47:968-973.
http://www.ncbi.nlm.nih.gov/pubmed/22102668

Cerletti C, Tamburrelli C, Izzi B, Gianfagna F, de Gaetano G (2011) Platelet-leukocyte interactions in thrombosis. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22075180

Cheng V, Kashyap SR, Schauer PR, Kirwan JP, McCrae KR (2011) Restoration of glycemic control in patients with type 2 diabetes mellitus after bariatric surgery is associated with reduction in microparticles. Surg Obes Relat Dis.
http://www.ncbi.nlm.nih.gov/pubmed/22093380

Christensen A, Jensen JT, Nohr AM, Cooper DL (2011) Room-Temperature-Stable Coagulation Factor VII Recombinant: Chemical and Microbiologic Stability Over 24 Hours During Continuous In VitroInfusion. Clin Ther.
http://www.ncbi.nlm.nih.gov/pubmed/22088413

Comes JF, Devignes J, Thiebaugeorges O, Briquel ME, Lecompte T (2011) Prophylactic use of a recombinant activated factor VII in delivery haemorrhage by caesarean in a woman with major factor VII deficiency: a case report. Ann Biol Clin (Paris) 69:713-719.
http://www.ncbi.nlm.nih.gov/pubmed/22123573

Corlan AD, Ross J (2011) Canalization effect in the coagulation cascade and the interindividual variability of oral anticoagulant response. a simulation Study. Theor Biol Med Model 8:37.
http://www.ncbi.nlm.nih.gov/pubmed/22082142

Dirkmann D, Gorlinger K, Gisbertz C, Dusse F, Peters J (2011) Factor XIII and Tranexamic Acid But Not Recombinant Factor VIIa Attenuate Tissue Plasminogen Activator-Induced Hyperfibrinolysis in Human Whole Blood. Anesth Analg.
http://www.ncbi.nlm.nih.gov/pubmed/22104068

Egorina EM, Sovershaev TA, Hansen JB, Sovershaev MA (2011) BMP-2 inhibits TF expression in human monocytes by shutting down MAPK signaling and AP-1 transcriptional activity. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22119392

Fadzil F (2011) Recurrent intracranial haemorrhages in a patient with factor seven deficiency: a case report. Med J Malaysia 66:261-263.
http://www.ncbi.nlm.nih.gov/pubmed/22111455

Francischetti IM, Oliveira CJ, Ostera GR, Yager SB, Debierre-Grockiego F, Carregaro V, . . . Waisberg M (2011) Defibrotide Interferes With Several Steps of the Coagulation-Inflammation Cycle and Exhibits Therapeutic Potential to Treat Severe Malaria. Arterioscler Thromb Vasc Biol.
http://www.ncbi.nlm.nih.gov/pubmed/22116094

Fukushima T, Mikane T, Ono D, Oku S, Kobayashi H, Watanabe Y, . . . Tokioka H (2011) A case of acquired hemophilia A with massive hemothorax. J Anesth.
http://www.ncbi.nlm.nih.gov/pubmed/22086484

Graham EM, Atz AM, Gillis J, Desantis SM, Haney AL, Deardorff RL, . . . Spinale FG (2011) Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery. J Thorac Cardiovasc Surg.
http://www.ncbi.nlm.nih.gov/pubmed/22075061

Hay JW, Zhou ZY (2011) Systematic literature review of economics analysis on treatment of mild-to-moderate bleeds with aPCC versus rFVIIa. J Med Econ 14:516-525.
http://www.ncbi.nlm.nih.gov/pubmed/21699366

Henriquez S, Calderon C, Quezada M, Oliva B, Bravo ML, Aranda E, . . . Owen GI (2011) Progesterone utilizes distinct membrane pools of tissue factor to increase coagulation and invasion and these effects are inhibited by TFPI. J Cell Physiol 226:3278-3285.
http://www.ncbi.nlm.nih.gov/pubmed/21344386

Hibi K, Goto T, Shirahata A, Saito M, Kigawa G, Nemoto H, Sanada Y (2011) Detection of TFPI2 Methylation in the Serum of Gastric Cancer Patients. Anticancer Res 31:3835-3838.
http://www.ncbi.nlm.nih.gov/pubmed/22110206

Huang J, Liu XJ, Bao HR, Zhang Y, Tan EL, Liao JM (2011) [The relationship between coagulation/anticoagulation imbalance and oxidative stress in patients with chronic obstructive pulmonary disease]. Zhonghua Nei Ke Za Zhi 50:664-667.
http://www.ncbi.nlm.nih.gov/pubmed/22093558

Jia ZC, Wan YL, Tang JQ, Dai Y, Liu YC, Wang X, Zhu J (2011) Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation of c-Fos via ERK1/2 and p38 MAPK signaling pathways in human colon cancer cell. Int J Colorectal Dis.
http://www.ncbi.nlm.nih.gov/pubmed/22076613

Kanse SM, Declerck PJ, Ruf W, Broze G, Etscheid M (2011) Factor VII-Activating Protease Promotes the Proteolysis and Inhibition of Tissue Factor Pathway Inhibitor. Arterioscler Thromb Vasc Biol.
http://www.ncbi.nlm.nih.gov/pubmed/22116096

Katgi A, Ataca P, Kahraman S, Piskin O, Ozcan MA, Demirkan F, . . . Undar B (2011) Ischemic stroke after recombinant factor VIIa treatment in acquired hemophilia A patient. Blood Coagul Fibrinolysis.
http://www.ncbi.nlm.nih.gov/pubmed/22123285

Khan MM, Douglas SD, Benton TD (2011) Substance P-Neurokinin-1 receptor interaction upregulates monocyte tissue factor. J Neuroimmunol.
http://www.ncbi.nlm.nih.gov/pubmed/22115773

Lee CW, Park CS, Hwang I, Lee H, Park DW, Kang SJ, . . . Park SJ (2011) Comparison of ruptured coronary plaques in patients with unstable and stable clinical presentation. J Thromb Thrombolysis 32:150-157.
http://www.ncbi.nlm.nih.gov/pubmed/21505786

Lorenzet R, Napoleone E, Cutrone A, Donati MB (2011) Thrombosis and obesity: Cellular bases. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22078462

Machado GB, de Oliveira AV, Saliba AM, de Lima CD, Suassuna JH, Plotkowski MC (2011) Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis. Respir Res 12:104.
http://www.ncbi.nlm.nih.gov/pubmed/21819560

Mischke R (2011) Determination of canine coagulation factor VII. Vet J 190:305-306.
http://www.ncbi.nlm.nih.gov/pubmed/22108258

Morse BC, Dente CJ, Hodgman EI, Shaz BH, Nicholas JM, Wyrzykowski AD, . . . Feliciano DV (2011) The effects of protocolized use of recombinant factor VIIa within a massive transfusion protocol in a civilian level I trauma center. Am Surg 77:1043-1049.
http://www.ncbi.nlm.nih.gov/pubmed/21944521

Mu E, Chen S, Li X, Ma XC (2011) [The effect of factor VII activating protease treatment on proliferation and collagen synthesis of cultured human pulmonary fibroblasts]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 23:653-657.
http://www.ncbi.nlm.nih.gov/pubmed/22093309

Nakagomi A, Sasaki M, Ishikawa Y, Shibui T, Kosugi M, Endoh Y, . . . Mizuno K (2011) Upregulation of monocyte tissue factor activity is significantly associated with carotid intima-media thickness in patients with metabolic syndrome. J Atheroscler Thromb 18:475-486.
http://www.ncbi.nlm.nih.gov/pubmed/21483174

Orfeo T, Gissel M, Butenas S, Undas A, Brummel-Ziedins KE, Mann KG (2011) Anticoagulants and the propagation phase of thrombin generation. PLoS One 6:e27852.
http://www.ncbi.nlm.nih.gov/pubmed/22125631

Palojarvi A, Andersson S, Siitonen S, Janer C, Petaja J (2011) High tissue factor in lungs and plasma associates with respiratory morbidity in preterm infants. Acta Paediatr.
http://www.ncbi.nlm.nih.gov/pubmed/22107344

Pierfranceschi MG, Imberti D, Orlando S, Vallisa D, Michieletti E (2011) Effectiveness of recombinant activated factor VII in haemorragic cancer-related disseminated intravascular coagulation: a case report. Blood Transfus 9:336-338.
http://www.ncbi.nlm.nih.gov/pubmed/21251460

Poller L, Ibrahim S, Pattison A, Jespersen J (2011) INR derivation with the PT/INR Line simplified using a spreadsheet from the world wide web. J Clin Pathol 64:930-932.
http://www.ncbi.nlm.nih.gov/pubmed/21515693

Poursafa P, Kelishadi R, Moattar F, Rafiee L, Amin MM, Lahijanzadeh A, Javanmard SH (2011) Genetic variation in the association of air pollutants with a biomarker of vascular injury in children and adolescents in Isfahan, Iran. J Res Med Sci 16:733-740.
http://www.ncbi.nlm.nih.gov/pubmed/22091301

Pugh N, Jarvis GE, Koch A, Sakariassen KS, Davis B, Farndale RW (2011) The impact of factor Xa inhibition on axial dependent arterial thrombus formation triggered by a tissue factor rich surface. J Thromb Thrombolysis.
http://www.ncbi.nlm.nih.gov/pubmed/22120925

Sen P, Nayak R, Clark CA, Gopalakrishnan R, Esmon CT, Pendurthi UR, Rao LV (2011) Factor X binding to endothelial cell protein C receptor: comparison with factor VIIa and activated protein C. Blood 118:2635-2636.
http://www.ncbi.nlm.nih.gov/pubmed/21885613

Shimizu A, Yamada K, Robson SC, Sachs DH, Colvin RB (2011) Pathologic Characteristics of Transplanted Kidney Xenografts. J Am Soc Nephrol.
http://www.ncbi.nlm.nih.gov/pubmed/22114174

Su LL, Chong YS (2011) Massive obstetric haemorrhage with disseminated intravascular coagulopathy. Best Pract Res Clin Obstet Gynaecol.
http://www.ncbi.nlm.nih.gov/pubmed/22101177

Sun Q, Chen L, Gao M, Jiang W, Shao F, Li J, . . . Yu B (2011) Ruscogenin inhibits lipopolysaccharide-induced acute lung injury in mice: Involvement of tissue factor, inducible NO synthase and nuclear factor (NF)-kappaB. Int Immunopharmacol.
http://www.ncbi.nlm.nih.gov/pubmed/22079591

Tan CW, Najm J, Morel-Kopp MC, Teo J, Chen Q, Felbor U, Ward CM (2011) Severe FX deficiency caused by a previously unidentified 4-bp deletion compound heterozygous with a large deletion involving FVII and FX genes. Haemophilia.
http://www.ncbi.nlm.nih.gov/pubmed/22126652

Tarzia V, Bottio T, Buratto E, Spiezia L, Simioni P, Gerosa G (2011) The hazard of comparing apples and oranges: The proper indication for the use of recombinant activated clotting factor VII in cardiac surgery. J Thorac Cardiovasc Surg 142:1588-1589.
http://www.ncbi.nlm.nih.gov/pubmed/22093717

Wilson JX, Wu F (2012) Vitamin C in sepsis. Subcell Biochem 56:67-83.
http://www.ncbi.nlm.nih.gov/pubmed/22116695

Wolberg AS, Aleman MM, Leiderman K, Machlus KR (2011) Procoagulant Activity in Hemostasis and Thrombosis: Virchow's Triad Revisited. Anesth Analg.
http://www.ncbi.nlm.nih.gov/pubmed/22104070

Ye R, Ye C, Huang Y, Liu L, Wang S (2011) Circulating tissue factor positive microparticles in patients with acute recurrent deep venous thrombosis. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22099707

Zhang Q, Liu XJ, Hu L, Liao DS, Zheng YB, Zhen YS, Song X (2011) Factor VII light chain-targeted lidamycin targets tissue factor-overexpressing tumor cells for cancer therapy. Int J Mol Med.
http://www.ncbi.nlm.nih.gov/pubmed/22108624

Zheng F, Jin Y, Wang M, Niu Z, Xu P, Xie H (2011) Congenital combined deficiency of factor VII and X in a patient due to accidental diphacinone intoxication. Thromb Haemost 106:180-181.
http://www.ncbi.nlm.nih.gov/pubmed/21544315

Zhou F, Zhou H, Wang T, Mu Y, Wu B, Guo DL, . . . Wu Y (2011) Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro. Acta Pharmacol Sin.
http://www.ncbi.nlm.nih.gov/pubmed/22101170
__________________________________________________________

Monday, November 14, 2011

Vol. 17, No. 22

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 22 November 15, 2011

(The next issue will be on December 1, 2011)

__________________________________________________________
TRIGGER is also available by RSS Feed:

http://feeds.feedburner.com/blogspot/glro

and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________

ANNOUNCEMENTS
PODCASTS FROM XXIIIrd ISTH CONGRESS
Selected talks from this summer's ISTH Congress in Kyoto are now available as webcasts (apparently open only to ISTH members) from:
http://www.multiwebcast.com/isth/2011/kyoto

The presentations can also be accessed through the"TALKS on the GO" iPhone/iPad/iPod Webcast App. Visit:
http://www.talksonthego.com/
or download it through the App Store by doing a search for: Talks on the Go (Latest version 1.1.0 of the Application approved by Apple Inc. on July 14th features an advanced Search Engine giving results by relevance according to slide content).
__________________________________________________________
PAPERS IN PRESS

None submitted for this issue.
__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI

THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1DASuMz6ItibCo-YOGCD8JG/

(2011) Obesity: Inhibition of tissue factor signaling-new antiobesity target? Nat Rev Endocrinol.
http://www.ncbi.nlm.nih.gov/pubmed/22064499

Altmae S, Salumets A, Bjuresten K, Kallak TK, Wanggren K, Landgren BM, . . . Stavreus-Evers A (2011) Tissue factor and tissue factor pathway inhibitors TFPI and TFPI2 in human secretory endometrium--possible link to female infertility. Reprod Sci 18:666-678.
http://www.ncbi.nlm.nih.gov/pubmed/21421890

Cheng S, Jiang Z, Zou Y, Chen C, Wang Y, Liu Y, . . . Wang Z (2011) Downregulation of Clock in circulatory system leads to an enhancement of fibrinolysis in mice. Exp Biol Med (Maywood) 236:1078-1084.
http://www.ncbi.nlm.nih.gov/pubmed/21750017

Dahab AA, Aburass R, Shawkat W, Babgi R, Essa O, Mujallid RH (2011) Full-term extrauterine abdominal pregnancy: a case report. J Med Case Reports 5:531.
http://www.ncbi.nlm.nih.gov/pubmed/22040324

Emmerechts J, Jacobs L, Van Kerckhoven S, Loyen S, Mathieu C, Fierens F, . . . Hoylaerts MF (2011) Air Pollution-Associated Procoagulant Changes: role of Circulating Microvesicles. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/22066779

Evangelho JS, Casali KR, Campos C, De Angelis K, Veiga AB, Rigatto K
(2011) Hypercholesterolemia magnitude increases sympathetic modulation and coagulation in LDLr knockout mice. Auton Neurosci 159:98-103.
http://www.ncbi.nlm.nih.gov/pubmed/20719578

Ferrari L, Podda GM (2011) Off-label use of recombinant activated coagulation factor VII for bleeding may raise the risk of arterial thrombosis. Intern Emerg Med 6:261-262.
http://www.ncbi.nlm.nih.gov/pubmed/21541718

Godier A, Miclot A, Le Bonniec B, Durand M, Fischer AM, Emmerich J, . . . Samama CM (2011) Evaluation of Prothrombin Complex Concentrate and Recombinant Activated Factor VII to Reverse Rivaroxaban in a Rabbit Model. Anesthesiology.
http://www.ncbi.nlm.nih.gov/pubmed/22042412

Hayanga AJ (2011) Off-label use of recombinant factor VIIa. Ann Intern Med 155:337-338; author reply 338-339.
http://www.ncbi.nlm.nih.gov/pubmed/21893632

Horowitz NA, Blevins EA, Miller WM, Perry AR, Talmage KE, Mullins ES, . . . Palumbo JS (2011) Thrombomodulin is a determinant of metastasis through a mechanism linked to the thrombin binding domain but not the lectin-like domain. Blood 118:2889-2895.
http://www.ncbi.nlm.nih.gov/pubmed/21788337

Jian P, Yan WS, Chao SL, Liang P, Zhen L, Ling QB, . . . Jian N (2011) Promoter of TFPI-2 is Hypermethylated in Chinese Pediatric Acute Myeloid Leukemia. J Pediatr Hematol Oncol.
http://www.ncbi.nlm.nih.gov/pubmed/22052167

Jordan SW, Chaikof EL (2011) Simulated surface-induced thrombin generation in a flow field. Biophys J 101:276-286.
http://www.ncbi.nlm.nih.gov/pubmed/21767479

Karkouti K, Levy JH (2011) A hemorrhage of off-label use. Ann Intern Med 155:339; author reply 339-340.
http://www.ncbi.nlm.nih.gov/pubmed/21893634

Kung CW, Lee YM, Yen MH (2011) In vivo anticoagulant effect of ethyl pyruvate in endotoxemic rats. Thromb Res 127:582-588.
http://www.ncbi.nlm.nih.gov/pubmed/21396682

Mlynarsky L, Bejarano-Achache I, Muszkat M, Caraco Y (2011) Factor VII R353Q genetic polymorphism is associated with altered warfarin sensitivity among CYP2C9 *1/*1 carriers. Eur J Clin Pharmacol.
http://www.ncbi.nlm.nih.gov/pubmed/22071881

Monteiro RQ (2011) Tissue factor as a target for the treatment of disseminated intravascular coagulation. Thromb Res 127:495-496.
http://www.ncbi.nlm.nih.gov/pubmed/21531009

Nascimento B, Lin Y, Callum J, Reis M, Pinto R, Rizoli S (2011) Recombinant factor VIIa is associated with an improved 24-hour survival without an improvement in inpatient survival in massively transfused civilian trauma patients. Clinics (Sao Paulo) 66:101-106.
http://www.ncbi.nlm.nih.gov/pubmed/21437444

Petrillo G, Cirillo P, D'Ascoli GL, Maresca F, Ziviello F, Chiariello M (2010) Tissue Factor/Factor FVII Complex Inhibitors in Cardiovascular Disease. Are Things Going Well? Curr Cardiol Rev 6:325-332.
http://www.ncbi.nlm.nih.gov/pubmed/22043208

Phillips A (2011) Off-label use of recombinant factor VIIa. Ann Intern Med 155:337; author reply 338-339.
http://www.ncbi.nlm.nih.gov/pubmed/21893633

Schweintzger S, Schlagenhauf A, Leschnik B, Rinner B, Bernhard H, Novak M, Muntean W (2011) Microparticles in newborn cord blood: slight elevation after normal delivery. Thromb Res 128:62-67.
http://www.ncbi.nlm.nih.gov/pubmed/21376371

Tian M, Wan Y, Tang J, Li H, Yu G, Zhu J, . . . Zhu S (2011) Depletion of tissue factor suppresses hepatic metastasis and tumor growth in colorectal cancer via the downregulation of MMPs and the induction of autophagy and apoptosis. Cancer Biol Ther 12.
http://www.ncbi.nlm.nih.gov/pubmed/22052255

Tormoen GW, Rugonyi S, Gruber A, McCarty OJ (2011) The role of carrier number on the procoagulant activity of tissue factor in blood and plasma. Phys Biol 8:066005.
http://www.ncbi.nlm.nih.gov/pubmed/22048420

van den Berg YW, Osanto S, Reitsma PH, Versteeg HH (2011) The relationship between tissue factor and cancer progression: insights from bench and bedside. Blood.
http://www.ncbi.nlm.nih.gov/pubmed/22065595

van den Hengel LG, van den Berg YW, Reitsma PH, Bos MH, Versteeg HH (2011) Evolutionary Conservation of the Tissue Factor Disulfide Bonds and Identification of a Possible Oxidoreductase Binding Motif. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/22066736

Zahra S, Anderson JA, Stirling D, Ludlam CA (2011) Plasma microparticles are not elevated in fresh plasma from patients with gynaecological malignancy--an observational study. Gynecol Oncol 123:152-156.
http://www.ncbi.nlm.nih.gov/pubmed/21777967

Zhang N, Lawrence DA (2011) Tissue factor and obesity, a two-way street. Nat Med 17:1343-1344.
http://www.ncbi.nlm.nih.gov/pubmed/22064407

Zhou RF, Liu Y, Wang YX, Mo W, Yu M (2011) Coagulation factor III (tissue factor) is required for vascularization in zebrafish embryos. Genet Mol Res 10.
http://www.ncbi.nlm.nih.gov/pubmed/22057990

Zhuang JL, Jiang QW, Xu Y, Wang SJ (2011) Recombinant activated factor VII in hemophagocytic lymphohistiocytosis with disseminated intravascular coagulation. Chin Med J (Engl) 124:3189-3191.
http://www.ncbi.nlm.nih.gov/pubmed/22040579
__________________________________________________________

Tuesday, November 1, 2011

Vol. 17, No. 21

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 21 November 1, 2011

(The next issue will be on November 15, 2011)

__________________________________________________________
TRIGGER is also available by RSS Feed:

http://feeds.feedburner.com/blogspot/glro

and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________

PAPERS IN PRESS

None submitted for this issue.
__________________________________________________________
UPCOMING MEETINGS & EVENTS
The 6th International Conference on Thrombosis and Hemostasis Issues in Cancer will be held in Bergamo, Italy, April 20-22, 2012. Online registration and abstract submission is now available. The abstract submission deadline is November 30th, 2011. For more information and to see the preliminary program, go to:
http://www.icthic.com/

* * * * * * * * * * *
Save the date:
6th Symposium on Hemostasis with Special Focus on Factor VIIa and Tissue Factor -- Hemostasis and Beyond will be held at the Carolina Inn, Chapel Hill, NC May 3-5, 2012. The link to the brochure and registration form should be available in December.
__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI

THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1TmEifV2v36Aj7jVbb-dCua/

Badeanlou L, Furlan-Freguia C, Yang G, Ruf W, Samad F (2011) Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation. Nat Med.
http://www.ncbi.nlm.nih.gov/pubmed/22019885

Balandina AN, Shibeko AM, Kireev DA, Novikova AA, Shmirev, II, Panteleev MA, Ataullakhanov FI (2011) Positive Feedback Loops for Factor V and Factor VII Activation Supply Sensitivity to Local Surface Tissue Factor Density During Blood Coagulation. Biophys J 101:1816-1824.
http://www.ncbi.nlm.nih.gov/pubmed/22004734

Benlakhal F, Mura T, Schved JF, Giansily-Blaizot M (2011) A retrospective analysis of 157 surgical procedures performed without replacement therapy in 83 unrelated factor VII-deficient patients. J Thromb Haemost 9:1149-1156.
http://www.ncbi.nlm.nih.gov/pubmed/21486425

Bhagirath VC, O'Malley L, Crowther MA (2011) Management of bleeding complications in the anticoagulated patient. Semin Hematol 48:285-294.
http://www.ncbi.nlm.nih.gov/pubmed/22000094

Chen D, Shrivastava S, Ma L, Tham EL, Abrahams J, Coe JD, . . . Dorling A (2011) Inhibition of Thrombin Receptor Signaling on alpha-Smooth Muscle Actin+ CD34+ Progenitors Leads to Repair After Murine Immune Vascular Injury. Arterioscler Thromb Vasc Biol.
http://www.ncbi.nlm.nih.gov/pubmed/22034512

Christensen MC, Banner C, Lefering R, Vallejo-Torres L, Morris S (2011) Quality of life after severe trauma: results from the global trauma trial with recombinant Factor VII. J Trauma 70:1524-1531.
http://www.ncbi.nlm.nih.gov/pubmed/21378585

Cocco E, Varughese J, Buza N, Bellone S, Glasgow M, Bellone M, . . . Santin AD (2011) Expression of tissue factor in adenocarcinoma and squamous cell carcinoma of the uterine cervix: implications for immunotherapy with hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor. BMC Cancer 11:263.
http://www.ncbi.nlm.nih.gov/pubmed/21693061

Davalos D, Akassoglou K (2011) Fibrinogen as a key regulator of inflammation in disease. Semin Immunopathol.
http://www.ncbi.nlm.nih.gov/pubmed/22037947

Dunne B, Xiao P, Andrews D (2011) Successful Use of Factor VIIa to Control Life-threatening Post-operative Haemorrhage in a Patient on Extra-Corporeal Membrane Oxygenation. Heart Lung Circ.
http://www.ncbi.nlm.nih.gov/pubmed/22036715

Dutton RP, Parr M, Tortella BJ, Champion HR, Bernard GR, Boffard K, . . . Hauser CJ (2011) Recombinant activated factor VII safety in trauma patients: results from the CONTROL trial. J Trauma 71:12-19.
http://www.ncbi.nlm.nih.gov/pubmed/21610529

Fischer TH, Nichols TC, Scull CM, Smith CJ, Demcheva M (2011) Poly-N-acetylglucosamine fibers amplify the effectiveness of recombinant factor VIIA on clot formation in hemophilia B canine blood. J Trauma 71:S171-175.
http://www.ncbi.nlm.nih.gov/pubmed/21814114

Gambone JE, Owens Iii AP, Mackman N (2011) Comment on "Tissue factor-dependent chemokine production aggravates experimental colitis'. Mol Med.
http://www.ncbi.nlm.nih.gov/pubmed/22027905

Gardiner C, Tannetta DS, Simms CA, Harrison P, Redman CW, Sargent IL (2011) Syncytiotrophoblast microvesicles released from pre-eclampsia placentae exhibit increased tissue factor activity. PLoS One 6:e26313.
http://www.ncbi.nlm.nih.gov/pubmed/22022598

Gessler F, Voss V, Seifert V, Gerlach R, Kogel D (2011) Knockdown of TFPI-2 promotes migration and invasion of glioma cells. Neurosci Lett 497:49-54.
http://www.ncbi.nlm.nih.gov/pubmed/21530612

Ghanny S, Warkentin TE, Crowther MA (2011) Reversing Anticoagulant Therapy. Curr Drug Discov Technol.
http://www.ncbi.nlm.nih.gov/pubmed/22023256

Huber AW, Raio L, Alberio L, Ghezzi F, Surbek DV (2011) Recombinant human factor VIIa prevents hysterectomy in severe postpartum hemorrhage: single center study. J Perinat Med.
http://www.ncbi.nlm.nih.gov/pubmed/22017328

Khorana AA (2011) Risk assessment and prophylaxis for VTE in cancer patients. J Natl Compr Canc Netw 9:789-797.
http://www.ncbi.nlm.nih.gov/pubmed/21715725

Krisl JC, Meadows HE, Greenberg CS, Mazur JE (2011) Clinical Usefulness of Recombinant Activated Factor VII in Patients with Liver Failure Undergoing Invasive Procedures. Ann Pharmacother 45:1433-1438.
http://www.ncbi.nlm.nih.gov/pubmed/22009992

Lee BJ, Kim JH, Woo SH, Kim DH, Yu YS (2011) Tissue factor is involved in retinoblastoma cell proliferation via both the Akt and extracellular signal-regulated kinase pathways. Oncol Rep 26:665-670.
http://www.ncbi.nlm.nih.gov/pubmed/21617868

Lesperance RN, Lehmann RK, Harold DM, Beekley AC, Sebesta JA, Martin MJ (2011) Recombinant Factor VIIa is Effective at Reversing Coagulopathy in a Lactic Acidosis Model. J Trauma.
http://www.ncbi.nlm.nih.gov/pubmed/22002618

Lockwood CJ (2011) Mechanisms of normal and abnormal endometrial bleeding. Menopause 18:408-411.
http://www.ncbi.nlm.nih.gov/pubmed/21499503

Mackman N, Davis GE (2011) Blood coagulation and blood vessel development: is tissue factor the missing link? Arterioscler Thromb Vasc Biol 31:2364-2366.
http://www.ncbi.nlm.nih.gov/pubmed/22011746

Mazzolai L, Bouzourene K, Hayoz D, Dignat-George F, Liu JW, Bounameaux H, . . . Kruithof EK (2011) Characterization of human late outgrowth endothelial progenitor-derived cells under various flow conditions. J Vasc Res 48:443-451.
http://www.ncbi.nlm.nih.gov/pubmed/21625177

Meadows HB, Krisl JC, Greenberg CS, Mazur JE (2011) The Use of Activated Recombinant Factor VII in a Patient with Fulminant Hepatic Failure Requiring Placement of an Intracranial Pressure Monitor. Ann Pharmacother 45:e60.
http://www.ncbi.nlm.nih.gov/pubmed/22028416

Mo X, Hao Y, Yang X, Chen S, Lu X, Gu D (2011) Association between polymorphisms in the coagulation factor VII gene and coronary heart disease risk in different ethnicities: a meta-analysis. BMC Med Genet 12:107.
http://www.ncbi.nlm.nih.gov/pubmed/21838885

Morfini M, Jimenez-Yuste V, Eichler H, Fischer R, Kirchmaier CM, Scharling B, Bjerre J (2011) Pharmacokinetic properties of two different recombinant activated factor VII formulations. Haemophilia.
http://www.ncbi.nlm.nih.gov/pubmed/21999231

Ostergaard H, Bjelke JR, Hansen L, Petersen LC, Pedersen AA, Elm T, . . . Tranholm M (2011) Prolonged half-life and preserved enzymatic properties of factor IX selectively PEGylated on native N-glycans in the activation peptide. Blood 118:2333-2341.
http://www.ncbi.nlm.nih.gov/pubmed/21700771

Puy C, Hermida J, Montes R (2011) Factor X and factor VII binding to endothelial protein C receptor differs between species. J Thromb Haemost 9:1255-1257.
http://www.ncbi.nlm.nih.gov/pubmed/21489130

Queiroz KC, Spek CA (2011) Response to Comment on "Tissue factor-dependent chemokine production aggravates experimental colitis'. Mol Med.
http://www.ncbi.nlm.nih.gov/pubmed/22027904

Rice TW, Morris S, Tortella BJ, Wheeler AP, Christensen MC (2011) Deviations from evidence based clinical management guidelines increase mortality in critically injured trauma patients. Crit Care Med.
http://www.ncbi.nlm.nih.gov/pubmed/22036858

Rochier A, Nixon A, Yamashita N, Abe R, Madri JA, Sumpio BE (2011) Laminar shear, but not orbital shear, has a synergistic effect with thrombin stimulation on tissue factor expression in human umbilical vein endothelial cells. J Vasc Surg 54:480-488.
http://www.ncbi.nlm.nih.gov/pubmed/21367569

Scola MR, Nichols TC, Zhu H, Caughey MC, Merricks EP, Raymer RA, . . . Gallippi CM (2011) ARFI Ultrasound Monitoring of Hemorrhage and Hemostasis In Vivo in Canine von Willebrand Disease and Hemophilia. Ultrasound Med Biol.
http://www.ncbi.nlm.nih.gov/pubmed/22033127

Sossdorf M, Otto GP, Claus RA, Gabriel HH, Losche W (2011) Cell-derived microparticles promote coagulation after moderate exercise. Med Sci Sports Exerc 43:1169-1176.
http://www.ncbi.nlm.nih.gov/pubmed/21131870

Stephan S, Schwarz H, Haude-Barten A, Sidelmann JJ, Fischer B, Althaus H, . . . Vitzthum F (2011) Direct chromogenic substrate immuno-capture activity assay for testing of factor VII-activating protease. Clin Chem Lab Med 49:1199-1204.
http://www.ncbi.nlm.nih.gov/pubmed/21663569

Svensson KJ, Kucharzewska P, Christianson HC, Skold S, Lofstedt T, Johansson MC, . . . Belting M (2011) Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells. Proc Natl Acad Sci U S A 108:13147-13152.
http://www.ncbi.nlm.nih.gov/pubmed/21788507

Tiede A, Friedrich U, Stenmo C, Allen G, Giangrande P, Goudemand J, . . . Berntorp E (2011) Safety and pharmacokinetics of subcutaneously administered recombinant activated factor VII (rFVIIa). J Thromb Haemost 9:1191-1199.
http://www.ncbi.nlm.nih.gov/pubmed/21489128

Yada K, Nogami K, Ogiwara K, Shibata M, Shima M (2011) Effects of anti-factor VIII inhibitor antibodies on factor VIIa/tissue factor-catalysed activation and inactivation of factor VIII. Thromb Haemost 105:989-998.
http://www.ncbi.nlm.nih.gov/pubmed/21437361
__________________________________________________________

Monday, October 17, 2011

Vol. 17, No. 20

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 20 October 17, 2011

(The next issue will be on November 1, 2011)

__________________________________________________________
TRIGGER is also available by RSS Feed:

http://feeds.feedburner.com/blogspot/glro

and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________

PAPERS IN PRESS

None submitted for this issue.
__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI

THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1BYJPJ6cwgn62nwiHh47fhU/

Aass HC, Ovstebo R, Troseid AM, Kierulf P, Berg JP, Henriksson CE (2011) Fluorescent particles in the antibody solution result in false TF- and CD14-positive microparticles in flow cytometric analysis. Cytometry A.
http://www.ncbi.nlm.nih.gov/pubmed/21990118

Abe R, Yamashita N, Rochier A, Nixon A, Madri JA, Sumpio BE (2011) Varying effects of hemodynamic forces on tissue factor RNA expression in human endothelial cells. J Surg Res 170:150-156.
http://www.ncbi.nlm.nih.gov/pubmed/21592524

Adams MJ, Palatinus A, Harvey A, Khalafallah A (2011) Impaired control of the tissue factor pathway of blood coagulation in systemic lupus erythematosus. Lupus.
http://www.ncbi.nlm.nih.gov/pubmed/21993387

Andrie RP, Bauriedel G, Braun P, Hopp HW, Nickenig G, Skowasch D (2011) Prevalence of intimal heat shock protein 60 homologues in unstable angina and correlation with anti-heat shock protein antibody titers. Basic Res Cardiol 106:657-665.
http://www.ncbi.nlm.nih.gov/pubmed/21416407

Antoniak S, Pawlinski R, Mackman N (2011) Protease-activated receptors and myocardial infarction. IUBMB Life 63:383-389.
http://www.ncbi.nlm.nih.gov/pubmed/21438116

Augoustides JG (2011) Advances in Anticoagulation: Focus on Dabigatran, an Oral Direct Thrombin Inhibitor. J Cardiothorac Vasc Anesth.
http://www.ncbi.nlm.nih.gov/pubmed/21982327

Ben-Hadj-Khalifa-Kechiche S, Hezard N, Poitevin S, Remy MG, Florent B, Mahjoub T, Nguyen P (2010) Differential inhibitory effect of fondaparinux on the procoagulant potential of intact monocytes and monocyte-derived microparticles. J Thromb Thrombolysis 30:412-418.
http://www.ncbi.nlm.nih.gov/pubmed/20602250

Bretz N, Noske A, Keller S, Erbe-Hofmann N, Schlange T, Salnikov AV, . . . Altevogt P (2011) CD24 promotes tumor cell invasion by suppressing tissue factor pathway inhibitor-2 (TFPI-2) in a c-Src-dependent fashion. Clin Exp Metastasis.
http://www.ncbi.nlm.nih.gov/pubmed/21984372

Di Santo A, Amore C, Dell'Elba G, Manarini S, Evangelista V (2011) Glycogen synthase kinase-3 negatively regulates tissue factor expression in monocytes interacting with activated platelets. J Thromb Haemost 9:1029-1039.
http://www.ncbi.nlm.nih.gov/pubmed/21320285

Emekli-Alturfan E, Basar I, Malali E, Elemek E, Oktay S, Ayan F, . . . Noyan U (2010) Plasma tissue factor levels and salivary tissue factor activities of periodontitis patients with and without cardiovascular disease. Pathophysiol Haemost Thromb 37:77-81.
http://www.ncbi.nlm.nih.gov/pubmed/21293108

Furlan-Freguia C, Marchese P, Gruber A, Ruggeri ZM, Ruf W (2011) P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. J Clin Invest 121:2932-2944.
http://www.ncbi.nlm.nih.gov/pubmed/21670495

Ge C, You Y, Zou P (2010) [Preliminary study on role of endothelial cells and tissue factor in graft-versus-host disease]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 18:1278-1281.
http://www.ncbi.nlm.nih.gov/pubmed/21129276

Gleeson EM, O'Donnell JS, Preston RJ (2011) The endothelial cell protein C receptor: cell surface conductor of cytoprotective coagulation factor signaling. Cell Mol Life Sci.
http://www.ncbi.nlm.nih.gov/pubmed/21968919

Guo D, Zhou H, Wu Y, Zhou F, Xu G, Wen H, Zhang X (2011) Involvement of ERK1/2/NF-kappaB signal transduction pathway in TF/FVIIa/PAR2-induced proliferation and migration of colon cancer cell SW620. Tumour Biol 32:921-930.
http://www.ncbi.nlm.nih.gov/pubmed/21625939

Harenberg J, Marx S, Kramer R, Giese C, Weiss C (2011) Determination of an international sensitivity index of thromboplastin reagents using a WHO thromboplastin as calibrator for plasma spiked with rivaroxaban. Blood Coagul Fibrinolysis.
http://www.ncbi.nlm.nih.gov/pubmed/21986465

Holmberg H, Elm T, Karpf D, Tranholm M, Bjorn SE, Stennicke H, Ezban M (2011) GlycoPEGylated rFVIIa (N7-GP) has a prolonged hemostatic effect in hemophilic mice compared with rFVIIa. J Thromb Haemost 9:1070-1072.
http://www.ncbi.nlm.nih.gov/pubmed/21366858

Jouannelle C, Giansily-Blaizot M, Monpoux F, Casagrande F, Poiree M, Berard E (2011) Spontaneous umbilical cord haematoma and congenital factor VII deficiency. Haemophilia.
http://www.ncbi.nlm.nih.gov/pubmed/21967451

Knudsen T, Olsen OH, Petersen LC (2011) Tissue factor and factor VIIa cross-species compatibility. Front Biosci 17:3196-3215.
http://www.ncbi.nlm.nih.gov/pubmed/21622229

Kurland DB, Hong C, Aarabi B, Gerzanich V, Simard JM (2011) Hemorrhagic Progression of a Contusion following Traumatic Brain Injury - a Review. J Neurotrauma.
http://www.ncbi.nlm.nih.gov/pubmed/21988198

Lopez-Vilchez I, Hedner U, Altisent C, Diaz-Ricart M, Escolar G, Galan AM (2011) Redistribution and hemostatic action of recombinant activated factor VII associated with platelets. Am J Pathol 178:2938-2948.
http://www.ncbi.nlm.nih.gov/pubmed/21641410

Matejovic M, Chvojka J, Sykora R, Krouzecky A, Radej J, Parizkova R, . . . Cerny V (2011) A 24-h work shift in intensive care personnel: biological pathways between work stress and ill health. J Int Med Res 39:629-636.
http://www.ncbi.nlm.nih.gov/pubmed/21672368

Mukherjee SD, Swystun LL, Mackman N, Wang JG, Pond G, Levine MN, Liaw PC (2010) Impact of chemotherapy on thrombin generation and on the protein C pathway in breast cancer patients. Pathophysiol Haemost Thromb 37:88-97.
http://www.ncbi.nlm.nih.gov/pubmed/21430357

Oishi K, Koyanagi S, Ohkura N (2011) Circadian mRNA expression of coagulation and fibrinolytic factors is organ-dependently disrupted in aged mice. Exp Gerontol.
http://www.ncbi.nlm.nih.gov/pubmed/21963655

Opstad TB, Pettersen AA, Bratseth V, Arnesen H, Seljeflot I (2010) The influence of tissue factor and tissue factor pathway inhibitor polymorphisms on thrombin generation in stable coronary artery disease. Pathophysiol Haemost Thromb 37:98-103.
http://www.ncbi.nlm.nih.gov/pubmed/21555871

Persson E, Olsen OH (2011) Allosteric activation of coagulation factor VIIa. Front Biosci 17:3156-3163.
http://www.ncbi.nlm.nih.gov/pubmed/21622226

Rancourt RC, Veress LA, Guo X, Jones TN, Hendry-Hofer TB, White CW (2011) Airway Tissue Factor-Dependent Coagulation Activity in Response to Sulfur Mustard Analog 2-chloroethyl ethyl sulfide (CEES). Am J Physiol Lung Cell Mol Physiol.
http://www.ncbi.nlm.nih.gov/pubmed/21964405

Schlunk F, Van Cott EM, Hayakawa K, Pfeilschifter W, Lo EH, Foerch C (2011) Recombinant Activated Coagulation Factor VII and Prothrombin Complex Concentrates Are Equally Effective in Reducing Hematoma Volume in Experimental Warfarin-Associated Intracerebral Hemorrhage. Stroke.
http://www.ncbi.nlm.nih.gov/pubmed/21998055

Semeraro F, Ammollo CT, Morrissey JH, Dale GL, Friese P, Esmon NL, Esmon CT (2011) Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4. Blood 118:1952-1961.
http://www.ncbi.nlm.nih.gov/pubmed/21673343

Simioni P, Spiezia L (2011) Factor VIIa-AT complex plasma levels and arterial thrombosis. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/21995975

Song Z, Jin R, Yu S, Nanda A, Granger DN, Li G (2011) Crucial Role of CD40 Signaling in Vascular Wall Cells in Neointimal Formation and Vascular Remodeling After Vascular Interventions. Arterioscler Thromb Vasc Biol.
http://www.ncbi.nlm.nih.gov/pubmed/21998133

Srinivasan R, Bogdanov VY (2011) Alternatively spliced tissue factor: discovery, insights, clinical implications. Front Biosci 17:3061-3071.
http://www.ncbi.nlm.nih.gov/pubmed/21622222

Tchaikovski SN, Thomassen MC, Costa S, Peeters LL, Rosing J (2011) Role of protein S and tissue factor pathway inhibitor in the development of activated protein C resistance early in pregnancy in women with a history of preeclampsia. Thromb Haemost 106.
http://www.ncbi.nlm.nih.gov/pubmed/21979881

Tokgoz H, Caliskan U, Lavigne-Lissalde G, Giansily-Blaizot M (2011) Successful prophylactic use of recombinant activated factor VII (rFVIIa) in a patient with congenital FVII deficiency and inhibitors to FVII. Haemophilia.
http://www.ncbi.nlm.nih.gov/pubmed/21973016

Vincent JL, Dutton R, Parr M, Hauser C (2011) Massive bleeding in polytrauma: how can we make progress? Crit Care 15:196.
http://www.ncbi.nlm.nih.gov/pubmed/21996523

Wertz D, Boveroux P, Peters P, Lenelle J, Franssen C (2011) Surgical resection of a sphenoid wing meningioma in a patient with Glanzmann thrombasthenia. Acta Anaesthesiol Belg 62:83-86.
http://www.ncbi.nlm.nih.gov/pubmed/21919374

Wu D, Xiong L, Wu S, Jiang M, Lian G, Wang M (2011) TFPI-2 methylation predicts poor prognosis in non-small cell lung cancer. Lung Cancer.
http://www.ncbi.nlm.nih.gov/pubmed/21983100

Yamamoto E, Kitano Y, Hasumi K (2011) Elucidation of Crucial Structures for a Catechol-Based Inhibitor of Plasma Hyaluronan-Binding Protein (Factor VII Activating Protease) Autoactivation. Biosci Biotechnol Biochem.
http://www.ncbi.nlm.nih.gov/pubmed/21979097

Zhou W, Schwarting S, Illanes S, Liesz A, Middelhoff M, Zorn M, . . . Veltkamp R (2011) Hemostatic Therapy in Experimental Intracerebral Hemorrhage Associated With the Direct Thrombin Inhibitor Dabigatran. Stroke.
http://www.ncbi.nlm.nih.gov/pubmed/21998060
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Monday, October 3, 2011

Vol. 17, No. 19

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 19 October 3, 2011

(The next issue will be on October 17, 2011)

__________________________________________________________
TRIGGER is also available by RSS Feed:

http://feeds.feedburner.com/blogspot/glro

and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________

PAPERS IN PRESS

None submitted for this issue.
__________________________________________________________
POSITIONS SOUGHT/AVAILABLE
Haematologic Technologies, Inc. in Essex Junction, VT is looking for laboratory technicians and PhD scientists to help us grow. Experience in protein chemistry and protein purification required. Please see our job posting on our website here:
http://www.haemtech.com/news.htm
__________________________________________________________
UPCOMING SCIENTIFIC MEETINGS

53rd ASH Annual Meeting. San Diego, CA, USA, December 10-13, 2011 (abstract deadline is past): http://www.hematology.org/Meetings/Annual-Meeting/

ATVB 2012 Scientific Sessions. Hilton Chicago, Chicago Illinois, April 18-20, 2012. Abstract deadline is January 5, 2012: http://my.americanheart.org/professional/Sessions/ATVB/ATVB_UCM_316902_SubHomePage.jsp

6th Symposium on Hemostasis: Special Focus on Tissue Factor, Factor VIIa and Tissue Factor Pathway Inhibitor. Carolina Inn, Chapel Hill, NC, May 3-5, 2012: http://www.med.unc.edu/www/events/6th-symposium-on-hemostasis

2012 Hemostasis Gordon Conference. Waterville Valley Resort, Waterville Valley, NH, July 22-27, 2012. Abstracts can be submitted for poster presentations: http://www.grc.org/programs.aspx?year=2012&program=hemostasis

http://www.grc.org/programs.aspx?year=2012&program=grs_hemo

__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI

THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1rExffZPU21QbyzIotgKoxH/

(2007) Utilization and Clinical Data on In-Hospital, Off-Label Uses of Recombinant Factor VIIa.
http://www.ncbi.nlm.nih.gov/pubmed/21938824

Abdel-Bakky MS, Hammad MA, Walker LA, Ashfaq MK (2011) Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice. Arch Toxicol 85:1245-1256.
http://www.ncbi.nlm.nih.gov/pubmed/21327618

Abel R, Salam NK, Shelley J, Farid R, Friesner RA, Sherman W (2011) Contribution of explicit solvent effects to the binding affinity of small-molecule inhibitors in blood coagulation factor serine proteases. ChemMedChem 6:1049-1066.
http://www.ncbi.nlm.nih.gov/pubmed/21506273

Agar C, de Groot PG, Marquart JA, Meijers JC (2011) Evolutionary conservation of the lipopolysaccharide binding site of beta2-glycoprotein I. Thromb Haemost 106.
http://www.ncbi.nlm.nih.gov/pubmed/21947351

Ando K, Ishibashi T, Ohkawara H, Inoue N, Sugimoto K, Uekita H, . . . Takeishi Y (2011) Crucial Role of Membrane Type 1 Matrix Metalloproteinase (MT1- MMP) in RhoA/Rac1-Dependent Signaling Pathways in Thrombin- Stimulated Endothelial Cells. J Atheroscler Thromb 18:762-773.
http://www.ncbi.nlm.nih.gov/pubmed/21628952

Blank M, Baraam L, Eisenstein M, Fridkin M, Dardik R, Heldman Y, . . . Shoenfeld Y (2011) beta2-Glycoprotein-I based peptide regulate endothelial-cells tissue-factor expression via negative regulation of pGSK3beta expression and reduces experimental-antiphospholipid-syndrome. J Autoimmun 37:8-17.
http://www.ncbi.nlm.nih.gov/pubmed/21524885

Butros L, Boayue K, Mathew P (2011) Current difficulties and recent advances in bypass therapy for the management of hemophilia with inhibitors: a new and practical formulation of recombinant factor VIIa. Drug Des Devel Ther 5:275-282.
http://www.ncbi.nlm.nih.gov/pubmed/21625417

Campello E, Spiezia L, Radu CM, Bulato C, Castelli M, Gavasso S, Simioni P (2011) Endothelial, platelet, and tissue factor-bearing microparticles in cancer patients with and without venous thromboembolism. Thromb Res 127:473-477.
http://www.ncbi.nlm.nih.gov/pubmed/21256535

Carlsson K, Persson E, Lindgren M, Carlsson U, Svensson M (2011) Effects on the conformation of FVIIa by sTF and Ca(2+) binding: Studies of fluorescence resonance energy transfer and quenching. Biochem Biophys Res Commun.
http://www.ncbi.nlm.nih.gov/pubmed/21924243

Cheng J, Xu J, Duanmu J, Zhou H, Booth CJ, Hu Z (2011) Effective Treatment of Human Lung Cancer by Targeting Tissue Factor with a Factor VII-Targeted Photodynamic Therapy. Curr Cancer Drug Targets.
http://www.ncbi.nlm.nih.gov/pubmed/21933104

Chu AJ (2011) Tissue factor, blood coagulation, and beyond: an overview. Int J Inflam 2011:367284.
http://www.ncbi.nlm.nih.gov/pubmed/21941675

De Rop C, Stadler M, Buchholz S, Eisert R, Ganser A, Trummer A (2011) Evaluation of tissue factor bearing microparticles as biomarkers in allogeneic stem-cell transplantation. Transplantation 92:351-358.
http://www.ncbi.nlm.nih.gov/pubmed/21681142

Di Nisio M, Baudo F, Cosmi B, D'Angelo A, De Gasperi A, Malato A, . . . Squizzato A (2011) Diagnosis and treatment of disseminated intravascular coagulation: Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET). Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/21930293

Dieterich M, Mann E, Wagner KF, Kramer-Steiner B, Reimer T, Gerber B, Stubert J (2011) Desmopressin-induced Moschcowitz-like syndrome after treatment of uterine atonic bleeding in a 28-year-old pregnant woman: case report and overview of the literature. Blood Coagul Fibrinolysis.
http://www.ncbi.nlm.nih.gov/pubmed/21921792

Ding L, Ma W, Littmann T, Camp R, Shen J (2011) The P2Y(2) nucleotide receptor mediates tissue factor expression in human coronary artery endothelial cells. J Biol Chem 286:27027-27038.
http://www.ncbi.nlm.nih.gov/pubmed/21652710

Disse J, Ruf W (2011) The endothelial protein C receptor is required for tissue factor ternary complex signaling in the mouse. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/21951329

Eisenreich A, Boltzen U, Malz R, Schultheiss HP, Rauch U (2011) Overexpression of alternatively spliced tissue factor induces the pro-angiogenic properties of murine cardiomyocytic HL-1 cells. Circ J 75:1235-1242.
http://www.ncbi.nlm.nih.gov/pubmed/21389637

Ettelaie C, Fountain D, Collier ME, Elkeeb AM, Xiao YP, Maraveyas A (2011) Low molecular weight heparin downregulates tissue factor expression and activity by modulating growth factor receptor-mediated induction of nuclear factor-kappaB. Biochim Biophys Acta.
http://www.ncbi.nlm.nih.gov/pubmed/21946214

Fang WQ, Zhang Q, Peng YB, Chen M, Lin XP, Wu JH, . . . Jin H (2011) Resistin level is positively correlated with thrombotic complications in Southern Chinese metabolic syndrome patients. J Endocrinol Invest 34:e36-42.
http://www.ncbi.nlm.nih.gov/pubmed/20671416

Gerotziafas GT, Galea V, Mbemba E, Kartechi A, Sassi M, Baccouche H, . . . Elalamy I (2011) Tissue factor over-expression by human pancreatic cancer cells BXPC3 is related to higher prothrombotic potential as compared to breast cancer cells MCF7. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/21917301

Henriquez S, Calderon C, Quezada M, Oliva B, Bravo ML, Aranda E, . . . Owen GI (2011) Progesterone utilizes distinct membrane pools of tissue factor to increase coagulation and invasion and these effects are inhibited by TFPI. J Cell Physiol.
http://www.ncbi.nlm.nih.gov/pubmed/21344386

Herrera RN, de Amaya EI, Aguilar RC, Turoni CJ, Maranon R, Berman SG, . . . de Bruno MP (2011) Inflammatory and prothrombotic activation with conserved endothelial function in patients with chronic, asymptomatic chagas disease. Clin Appl Thromb Hemost 17:502-507.
http://www.ncbi.nlm.nih.gov/pubmed/20699256

Holmberg H, Kiersgaard MK, Mikkelsen LF, Tranholm M (2011) Impact of blood sampling technique on blood quality and animal welfare in haemophilic mice. Lab Anim 45:114-120.
http://www.ncbi.nlm.nih.gov/pubmed/21382833

Holy EW, Forestier M, Richter EK, Akhmedov A, Leiber F, Camici GG, . . . Tanner FC (2011) Dietary alpha-linolenic acid inhibits arterial thrombus formation, tissue factor expression, and platelet activation. Arterioscler Thromb Vasc Biol 31:1772-1780.
http://www.ncbi.nlm.nih.gov/pubmed/21571683

Hvas AM, Boas TW, Jensen M, Lindskov C, Folkersen L, Ravn HB (2011) Change in Hemostatic Intervention After Implementation of Thromboelastometry. J Cardiothorac Vasc Anesth.
http://www.ncbi.nlm.nih.gov/pubmed/21924638

Ignjatovic V, Than J, Summerhayes R, Newall F, Horton S, Cochrane A, Monagle P (2011) Hemostatic response in paediatric patients undergoing cardiopulmonary bypass surgery. Pediatr Cardiol 32:621-627.
http://www.ncbi.nlm.nih.gov/pubmed/21360266

Jurk K, Lahav J, Van Aken H, Brodde MF, Nofer JR, Kehrel BE (2011) Extracellular Protein Disulfide Isomerase Regulates Feedback Activation of Platelet Thrombin Generation Via Modulation of Coagulation Factor Binding. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/21929690

Kacka K, Kacki W, Merak J, Bleka A (2010) Use of recombinant activated factor VII for reduction of perioperative blood loss during elective surgical correction of spine deformity in a Jehovah's Witness. Case report. Ortop Traumatol Rehabil 12:448-458.
http://www.ncbi.nlm.nih.gov/pubmed/21057153

Karkouti K, Levy JH (2011) Commentary: Recombinant Activated Factor VII: The Controversial Conundrum Regarding Its Off-Label Use. Anesth Analg 113:711-712.
http://www.ncbi.nlm.nih.gov/pubmed/21788315

Kassel KM, Owens III AP, Rockwell CE, Sullivan BP, Wang R, Tawfik O, . . . Luyendyk JP (2011) Protease-Activated Receptor 1 and Hematopoietic Cell Tissue Factor Are Required for Hepatic Steatosis in Mice Fed a High-Fat Diet. Am J Pathol.
http://www.ncbi.nlm.nih.gov/pubmed/21907177

Lee CN, Heidbrink JL, McKinnon K, Bushman V, Olsen H, Fitzhugh W, . . . Moore PA (2011) RNA Interference Characterization of Proteins Discovered by Proteomic Analysis of Pancreatic Cancer Reveals Function in Cell Growth and Survival. Pancreas.
http://www.ncbi.nlm.nih.gov/pubmed/21934552

Lhermusier T, Van Rottem J, Garcia C, Xuereb JM, Ragab A, Martin V, . . . Payrastre B (2011) The Syk-kinase inhibitor R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin-PF4 complex directed antibodies. J Thromb Haemost 9:2067-2076.
http://www.ncbi.nlm.nih.gov/pubmed/21848694

Liang HP, Brophy TM, Hogg PJ (2011) Redox properties of the tissue factor Cys186-Cys209 disulfide bond. Biochem J 437:455-460.
http://www.ncbi.nlm.nih.gov/pubmed/21595632

Lima LG, Oliveira AS, Campos LC, Bonamino M, Chammas R, Werneck C, . . . Monteiro RQ (2011) Malignant transformation in melanocytes is associated with increased production of procoagulant microvesicles. Thromb Haemost 106:712-723.
http://www.ncbi.nlm.nih.gov/pubmed/21800005

Lisman T, Porte RJ (2011) Recombinant factor VIIa to treat severe bleeding in patients with liver disease: Pitfalls and possibilities. J Hepatol 55:950-951.
http://www.ncbi.nlm.nih.gov/pubmed/21925325

Luo D, Szaba FM, Kummer LW, Plow EF, Mackman N, Gailani D, Smiley ST (2011) Protective roles for fibrin, tissue factor, plasminogen activator inhibitor-1, and thrombin activatable fibrinolysis inhibitor, but not factor XI, during defense against the gram-negative bacterium Yersinia enterocolitica. J Immunol 187:1866-1876.
http://www.ncbi.nlm.nih.gov/pubmed/21724997

Luporsi P, Chopard R, Janin S, Racadot E, Bernard Y, Ecarnot F, . . . Schiele F (2011) Use of recombinant factor VIIa (NovoSeven((R))) in 8 patients with ongoing life-threatening bleeding treated with fondaparinux. Acute Card Care 13:93-98.
http://www.ncbi.nlm.nih.gov/pubmed/21517672

Ma Z, Zhang T, Wang R, Cheng Z, Xu H, Li W, . . . Wang X (2011) Tissue factor-factor VIIa complex induces epithelial ovarian cancer cell invasion and metastasis through a monocytes-dependent mechanism. Int J Gynecol Cancer 21:616-624.
http://www.ncbi.nlm.nih.gov/pubmed/21543928

Marchetti M, Russo L, Balducci D, Falanga A (2011) All trans-retinoic acid modulates the procoagulant activity of human breast cancer cells. Thromb Res 128:368-374.
http://www.ncbi.nlm.nih.gov/pubmed/21458031

Martinez-Sales V, Vila V, Mico L, Contreras MT, Escandell A, Reganon E (2011) [Circulating endothelial cells and microparticles in patients with antiphospholipid antibodies]. Med Clin (Barc) 136:431-433.
http://www.ncbi.nlm.nih.gov/pubmed/21051055

Mast AE (2011) Alternatively spliced tissue factor pathway inhibitor: functional implications. Front Biosci (Schol Ed) 3:1457-1462.
http://www.ncbi.nlm.nih.gov/pubmed/21622281

Mazer CD, Leong-Poi H, Chhina T, Alfardan Z, Lapierre H, Wang Z, . . . Teitel J (2011) Recombinant factor VIIa affects anastomotic patency of vascular grafts in a rabbit model. J Thorac Cardiovasc Surg 142:418-423.
http://www.ncbi.nlm.nih.gov/pubmed/21281943

Meziani F, Delabranche X, Asfar P, Toti F (2010) Bench-to-bedside review: circulating microparticles--a new player in sepsis? Crit Care 14:236.
http://www.ncbi.nlm.nih.gov/pubmed/21067540

Mitrophanov AY, Reifman J (2011) Kinetic modeling sheds light on the mode of action of recombinant factor VIIa on thrombin generation. Thromb Res 128:381-390.
http://www.ncbi.nlm.nih.gov/pubmed/21641634

Morse BC, Dente CJ, Hodgman EI, Shaz BH, Nicholas JM, Wyrzykowski AD, . . . Feliciano DV (2011) The Effects of Protocolized Use of Recombinant Factor VIIa Within a Massive Transfusion Protocol in a Civilian Level I Trauma Center. Am Surg 77:1043-1049.
http://www.ncbi.nlm.nih.gov/pubmed/21944521

Nadir Y, Kenig Y, Drugan A, Shafat I, Brenner B (2011) An assay to evaluate heparanase procoagulant activity. Thromb Res 128:e3-e8.
http://www.ncbi.nlm.nih.gov/pubmed/21481923

Natorska J, Wypasek E, Grudzien G, Sobczyk D, Marek G, Filip G, . . . Undas A (2011) Does Diabetes Accelerate the Progression of Aortic Stenosis through Enhanced Inflammatory Response within Aortic valves? Inflammation.
http://www.ncbi.nlm.nih.gov/pubmed/21935671

Naumnik B, Rydzewska-Rosolowska A, Mysliwiec M (2011) Different Effects of Enoxaparin, Nadroparin, and Dalteparin on Plasma TFPI During Hemodialysis: A Prospective Crossover Randomized Study. Clin Appl Thromb Hemost 17:480-486.
http://www.ncbi.nlm.nih.gov/pubmed/20682597

Oehmcke S, Morgelin M, Malmstrom J, Linder A, Chew M, Thorlacius H, Herwald H (2011) Stimulation of blood mononuclear cells with bacterial virulence factors leads to the release of pro-coagulant and pro-inflammatory microparticles. Cell Microbiol.
http://www.ncbi.nlm.nih.gov/pubmed/21951918

Ogiwara K, Nogami K, Shima M (2011) Factor VIII activation by factor VIIa analog (V158D/E296V/M298Q) in tissue factor-independent mechanisms. Thromb Haemost 106:665-674.
http://www.ncbi.nlm.nih.gov/pubmed/21901232

Perez-Ferrer A, Gredilla E, de Vicente J, Laporta Y (2011) Cardiac Surgery Without Blood Products in a Jehovah's Witness Child With Factor VII Deficiency. J Cardiothorac Vasc Anesth.
http://www.ncbi.nlm.nih.gov/pubmed/21924639

Pinazo MJ, Tassies D, Munoz J, Fisa R, de Jesus Posada E, Monteagudo J, . . . Gascon J (2011) Hypercoagulability biomarkers in Trypanosoma cruzi -infected patients. Thromb Haemost 106:617-623.
http://www.ncbi.nlm.nih.gov/pubmed/21866301

Raffa S, Reverter JC, Seijo S, Tassies D, Abraldes JG, Bosch J, Garcia-Pagan JC (2011) Hypercoagulability in Patients with Chronic Non-Cirrhotic Portal Vein Thrombosis. Clin Gastroenterol Hepatol.
http://www.ncbi.nlm.nih.gov/pubmed/21946303

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