Monday, December 12, 2011

Vol. 17, No. 23

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 23 December 1, 2011
(The next issue will be on December 15, 2011)
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TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
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POSITIONS SOUGHT/AVAILABLE
The UNC McAllister Heart Institute, in collaboration with the departments in the School of Medicine and across the entire University, seeks outstanding candidates for an open-rank position at all levels of basic/translational research. This recruitment seeks a research scientist/physician interested in cardiovascular disease, including but not limited to vascular development, angiogenesis, cardiac pathology, and thrombosis. Applicants should have a strong record of recent accomplishments as a post-doctoral fellow or sustained productivity as an established faculty member. Academic credentials and experience will determine rank, track, and salary in an appropriate academic department. Applications will be reviewed beginning November 10, 2011 and until the position is filled.

Applicants must submit a letter of interest, curriculum vitae, a description of research plans, and names of four references through UNC Chapel Hill's web-based system. PDF documents are preferred. The following link will direct you to the position:
http://jobs.unc.edu/2502018

UNC McAllister Heart Institute and the University of North Carolina is an Equal Opportunity Employer. Hiring is contingent upon eligibility to work in the United States. Women and minorities are encouraged to apply.
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PAPERS IN PRESS
None submitted for this issue.
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RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1felWqyBWcGWhnjhWiipypk/

Alstrom U, Levin LA, Stahle E, Svedjeholm R, Friberg O (2011) Cost analysis of re-exploration for bleeding after coronary artery bypass graft surgery. Br J Anaesth.
http://www.ncbi.nlm.nih.gov/pubmed/22113929

Bhananker SM, Ramaiah R (2011) Trends in trauma transfusion. Int J Crit Illn Inj Sci 1:51-56.
http://www.ncbi.nlm.nih.gov/pubmed/22096774

Bouchama A, Al-Mohanna F, Assad L, Baturcam E, Eldali A, Owaidah T, Dehbi M (2011) Tissue factor/factor VIIa pathway mediates coagulation activation in induced-heat stroke in the baboon. Crit Care Med.
http://www.ncbi.nlm.nih.gov/pubmed/22080642

Busch JD, Van Andel R, Cordova J, Colman RE, Keim P, Rocke TE, . . . Wagner DM (2011) Population Differences in Host Immune Factors May Influence Survival of Gunnison's Prairie Dogs (Cynomys gunnisoni) during Plague Outbreaks. J Wildl Dis 47:968-973.
http://www.ncbi.nlm.nih.gov/pubmed/22102668

Cerletti C, Tamburrelli C, Izzi B, Gianfagna F, de Gaetano G (2011) Platelet-leukocyte interactions in thrombosis. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22075180

Cheng V, Kashyap SR, Schauer PR, Kirwan JP, McCrae KR (2011) Restoration of glycemic control in patients with type 2 diabetes mellitus after bariatric surgery is associated with reduction in microparticles. Surg Obes Relat Dis.
http://www.ncbi.nlm.nih.gov/pubmed/22093380

Christensen A, Jensen JT, Nohr AM, Cooper DL (2011) Room-Temperature-Stable Coagulation Factor VII Recombinant: Chemical and Microbiologic Stability Over 24 Hours During Continuous In VitroInfusion. Clin Ther.
http://www.ncbi.nlm.nih.gov/pubmed/22088413

Comes JF, Devignes J, Thiebaugeorges O, Briquel ME, Lecompte T (2011) Prophylactic use of a recombinant activated factor VII in delivery haemorrhage by caesarean in a woman with major factor VII deficiency: a case report. Ann Biol Clin (Paris) 69:713-719.
http://www.ncbi.nlm.nih.gov/pubmed/22123573

Corlan AD, Ross J (2011) Canalization effect in the coagulation cascade and the interindividual variability of oral anticoagulant response. a simulation Study. Theor Biol Med Model 8:37.
http://www.ncbi.nlm.nih.gov/pubmed/22082142

Dirkmann D, Gorlinger K, Gisbertz C, Dusse F, Peters J (2011) Factor XIII and Tranexamic Acid But Not Recombinant Factor VIIa Attenuate Tissue Plasminogen Activator-Induced Hyperfibrinolysis in Human Whole Blood. Anesth Analg.
http://www.ncbi.nlm.nih.gov/pubmed/22104068

Egorina EM, Sovershaev TA, Hansen JB, Sovershaev MA (2011) BMP-2 inhibits TF expression in human monocytes by shutting down MAPK signaling and AP-1 transcriptional activity. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22119392

Fadzil F (2011) Recurrent intracranial haemorrhages in a patient with factor seven deficiency: a case report. Med J Malaysia 66:261-263.
http://www.ncbi.nlm.nih.gov/pubmed/22111455

Francischetti IM, Oliveira CJ, Ostera GR, Yager SB, Debierre-Grockiego F, Carregaro V, . . . Waisberg M (2011) Defibrotide Interferes With Several Steps of the Coagulation-Inflammation Cycle and Exhibits Therapeutic Potential to Treat Severe Malaria. Arterioscler Thromb Vasc Biol.
http://www.ncbi.nlm.nih.gov/pubmed/22116094

Fukushima T, Mikane T, Ono D, Oku S, Kobayashi H, Watanabe Y, . . . Tokioka H (2011) A case of acquired hemophilia A with massive hemothorax. J Anesth.
http://www.ncbi.nlm.nih.gov/pubmed/22086484

Graham EM, Atz AM, Gillis J, Desantis SM, Haney AL, Deardorff RL, . . . Spinale FG (2011) Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery. J Thorac Cardiovasc Surg.
http://www.ncbi.nlm.nih.gov/pubmed/22075061

Hay JW, Zhou ZY (2011) Systematic literature review of economics analysis on treatment of mild-to-moderate bleeds with aPCC versus rFVIIa. J Med Econ 14:516-525.
http://www.ncbi.nlm.nih.gov/pubmed/21699366

Henriquez S, Calderon C, Quezada M, Oliva B, Bravo ML, Aranda E, . . . Owen GI (2011) Progesterone utilizes distinct membrane pools of tissue factor to increase coagulation and invasion and these effects are inhibited by TFPI. J Cell Physiol 226:3278-3285.
http://www.ncbi.nlm.nih.gov/pubmed/21344386

Hibi K, Goto T, Shirahata A, Saito M, Kigawa G, Nemoto H, Sanada Y (2011) Detection of TFPI2 Methylation in the Serum of Gastric Cancer Patients. Anticancer Res 31:3835-3838.
http://www.ncbi.nlm.nih.gov/pubmed/22110206

Huang J, Liu XJ, Bao HR, Zhang Y, Tan EL, Liao JM (2011) [The relationship between coagulation/anticoagulation imbalance and oxidative stress in patients with chronic obstructive pulmonary disease]. Zhonghua Nei Ke Za Zhi 50:664-667.
http://www.ncbi.nlm.nih.gov/pubmed/22093558

Jia ZC, Wan YL, Tang JQ, Dai Y, Liu YC, Wang X, Zhu J (2011) Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation of c-Fos via ERK1/2 and p38 MAPK signaling pathways in human colon cancer cell. Int J Colorectal Dis.
http://www.ncbi.nlm.nih.gov/pubmed/22076613

Kanse SM, Declerck PJ, Ruf W, Broze G, Etscheid M (2011) Factor VII-Activating Protease Promotes the Proteolysis and Inhibition of Tissue Factor Pathway Inhibitor. Arterioscler Thromb Vasc Biol.
http://www.ncbi.nlm.nih.gov/pubmed/22116096

Katgi A, Ataca P, Kahraman S, Piskin O, Ozcan MA, Demirkan F, . . . Undar B (2011) Ischemic stroke after recombinant factor VIIa treatment in acquired hemophilia A patient. Blood Coagul Fibrinolysis.
http://www.ncbi.nlm.nih.gov/pubmed/22123285

Khan MM, Douglas SD, Benton TD (2011) Substance P-Neurokinin-1 receptor interaction upregulates monocyte tissue factor. J Neuroimmunol.
http://www.ncbi.nlm.nih.gov/pubmed/22115773

Lee CW, Park CS, Hwang I, Lee H, Park DW, Kang SJ, . . . Park SJ (2011) Comparison of ruptured coronary plaques in patients with unstable and stable clinical presentation. J Thromb Thrombolysis 32:150-157.
http://www.ncbi.nlm.nih.gov/pubmed/21505786

Lorenzet R, Napoleone E, Cutrone A, Donati MB (2011) Thrombosis and obesity: Cellular bases. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22078462

Machado GB, de Oliveira AV, Saliba AM, de Lima CD, Suassuna JH, Plotkowski MC (2011) Pseudomonas aeruginosa toxin ExoU induces a PAF-dependent impairment of alveolar fibrin turnover secondary to enhanced activation of coagulation and increased expression of plasminogen activator inhibitor-1 in the course of mice pneumosepsis. Respir Res 12:104.
http://www.ncbi.nlm.nih.gov/pubmed/21819560

Mischke R (2011) Determination of canine coagulation factor VII. Vet J 190:305-306.
http://www.ncbi.nlm.nih.gov/pubmed/22108258

Morse BC, Dente CJ, Hodgman EI, Shaz BH, Nicholas JM, Wyrzykowski AD, . . . Feliciano DV (2011) The effects of protocolized use of recombinant factor VIIa within a massive transfusion protocol in a civilian level I trauma center. Am Surg 77:1043-1049.
http://www.ncbi.nlm.nih.gov/pubmed/21944521

Mu E, Chen S, Li X, Ma XC (2011) [The effect of factor VII activating protease treatment on proliferation and collagen synthesis of cultured human pulmonary fibroblasts]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue 23:653-657.
http://www.ncbi.nlm.nih.gov/pubmed/22093309

Nakagomi A, Sasaki M, Ishikawa Y, Shibui T, Kosugi M, Endoh Y, . . . Mizuno K (2011) Upregulation of monocyte tissue factor activity is significantly associated with carotid intima-media thickness in patients with metabolic syndrome. J Atheroscler Thromb 18:475-486.
http://www.ncbi.nlm.nih.gov/pubmed/21483174

Orfeo T, Gissel M, Butenas S, Undas A, Brummel-Ziedins KE, Mann KG (2011) Anticoagulants and the propagation phase of thrombin generation. PLoS One 6:e27852.
http://www.ncbi.nlm.nih.gov/pubmed/22125631

Palojarvi A, Andersson S, Siitonen S, Janer C, Petaja J (2011) High tissue factor in lungs and plasma associates with respiratory morbidity in preterm infants. Acta Paediatr.
http://www.ncbi.nlm.nih.gov/pubmed/22107344

Pierfranceschi MG, Imberti D, Orlando S, Vallisa D, Michieletti E (2011) Effectiveness of recombinant activated factor VII in haemorragic cancer-related disseminated intravascular coagulation: a case report. Blood Transfus 9:336-338.
http://www.ncbi.nlm.nih.gov/pubmed/21251460

Poller L, Ibrahim S, Pattison A, Jespersen J (2011) INR derivation with the PT/INR Line simplified using a spreadsheet from the world wide web. J Clin Pathol 64:930-932.
http://www.ncbi.nlm.nih.gov/pubmed/21515693

Poursafa P, Kelishadi R, Moattar F, Rafiee L, Amin MM, Lahijanzadeh A, Javanmard SH (2011) Genetic variation in the association of air pollutants with a biomarker of vascular injury in children and adolescents in Isfahan, Iran. J Res Med Sci 16:733-740.
http://www.ncbi.nlm.nih.gov/pubmed/22091301

Pugh N, Jarvis GE, Koch A, Sakariassen KS, Davis B, Farndale RW (2011) The impact of factor Xa inhibition on axial dependent arterial thrombus formation triggered by a tissue factor rich surface. J Thromb Thrombolysis.
http://www.ncbi.nlm.nih.gov/pubmed/22120925

Sen P, Nayak R, Clark CA, Gopalakrishnan R, Esmon CT, Pendurthi UR, Rao LV (2011) Factor X binding to endothelial cell protein C receptor: comparison with factor VIIa and activated protein C. Blood 118:2635-2636.
http://www.ncbi.nlm.nih.gov/pubmed/21885613

Shimizu A, Yamada K, Robson SC, Sachs DH, Colvin RB (2011) Pathologic Characteristics of Transplanted Kidney Xenografts. J Am Soc Nephrol.
http://www.ncbi.nlm.nih.gov/pubmed/22114174

Su LL, Chong YS (2011) Massive obstetric haemorrhage with disseminated intravascular coagulopathy. Best Pract Res Clin Obstet Gynaecol.
http://www.ncbi.nlm.nih.gov/pubmed/22101177

Sun Q, Chen L, Gao M, Jiang W, Shao F, Li J, . . . Yu B (2011) Ruscogenin inhibits lipopolysaccharide-induced acute lung injury in mice: Involvement of tissue factor, inducible NO synthase and nuclear factor (NF)-kappaB. Int Immunopharmacol.
http://www.ncbi.nlm.nih.gov/pubmed/22079591

Tan CW, Najm J, Morel-Kopp MC, Teo J, Chen Q, Felbor U, Ward CM (2011) Severe FX deficiency caused by a previously unidentified 4-bp deletion compound heterozygous with a large deletion involving FVII and FX genes. Haemophilia.
http://www.ncbi.nlm.nih.gov/pubmed/22126652

Tarzia V, Bottio T, Buratto E, Spiezia L, Simioni P, Gerosa G (2011) The hazard of comparing apples and oranges: The proper indication for the use of recombinant activated clotting factor VII in cardiac surgery. J Thorac Cardiovasc Surg 142:1588-1589.
http://www.ncbi.nlm.nih.gov/pubmed/22093717

Wilson JX, Wu F (2012) Vitamin C in sepsis. Subcell Biochem 56:67-83.
http://www.ncbi.nlm.nih.gov/pubmed/22116695

Wolberg AS, Aleman MM, Leiderman K, Machlus KR (2011) Procoagulant Activity in Hemostasis and Thrombosis: Virchow's Triad Revisited. Anesth Analg.
http://www.ncbi.nlm.nih.gov/pubmed/22104070

Ye R, Ye C, Huang Y, Liu L, Wang S (2011) Circulating tissue factor positive microparticles in patients with acute recurrent deep venous thrombosis. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22099707

Zhang Q, Liu XJ, Hu L, Liao DS, Zheng YB, Zhen YS, Song X (2011) Factor VII light chain-targeted lidamycin targets tissue factor-overexpressing tumor cells for cancer therapy. Int J Mol Med.
http://www.ncbi.nlm.nih.gov/pubmed/22108624

Zheng F, Jin Y, Wang M, Niu Z, Xu P, Xie H (2011) Congenital combined deficiency of factor VII and X in a patient due to accidental diphacinone intoxication. Thromb Haemost 106:180-181.
http://www.ncbi.nlm.nih.gov/pubmed/21544315

Zhou F, Zhou H, Wang T, Mu Y, Wu B, Guo DL, . . . Wu Y (2011) Epigallocatechin-3-gallate inhibits proliferation and migration of human colon cancer SW620 cells in vitro. Acta Pharmacol Sin.
http://www.ncbi.nlm.nih.gov/pubmed/22101170
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ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.

DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
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