TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 16, No. 10 May 19, 2010
(The next issue will be on June 1, 2010)
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PAPERS IN PRESS
None submitted for this issue.
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FACULTY POSITION AVAILABLE
Faculty Positions: Thrombosis, Hemostasis, and Vascular Biology Blood Research Institute, Blood Center of Wisconsin
The Blood Research Institute of BloodCenter of Wisconsin is undergoing a vigorous expansion of its basic and translational research programs, and is seeking qualified Ph.D. and M.D. research investigators who work in the areas of Thrombosis, Hemostasis, and Vascular Biology. While applications are welcome from scientists at all career levels, those individuals having recently completed strong productive postdoctoral research training are especially encouraged to apply. Generous start-up packages, well-equipped office and laboratory space, and high-level grant and administrative support will be provided.
The BRI is located on the campus of the Milwaukee Regional Medical Center in Wauwatosa, Wisconsin, a near-western suburb of Milwaukee - approximately seven miles from the BloodCenter Headquarters Building in downtown Milwaukee. The BRI is connected by a series of heated bridges and tunnels to the Medical College of Wisconsin (MCW) and Children's Hospital of Wisconsin (CHW). The proximity of the BRI with the clinical and research operations of MCW and CHW promote productive interactions between our investigative staff, the faculty in the basic and clinical science departments at MCW and CHW, and the nearby major adult teaching hospital.
Current areas of expertise of the BRI Research Faculty lie in the areas of platelet research, hemostasis and thrombosis, transplantation immunobiology, vascular biology, immunohematology and transfusion medicine. Faculty are encouraged to obtain faculty appointments at MCW in either basic or clinical Departments, and develop interactions as appropriate with MCW's Cardiovascular Research Center, Cancer Center, and Bone Marrow Transplant Program.
Applications will be accepted from May 1st - July 1st, or until the positions are filled. Applicants should email a letter of application, an updated CV, and the names of three references to:
Peter J. Newman, Ph.D.
Chair, THVB Faculty Search Committee
peter DOT newman AT bcw DOT edu
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RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1xEzo4dW1qf7GOdsaZ14Omu/
Altman R, Scazziota A, Herrera MD, and Gonzalez CD (2010) The hemostatic profile of recombinant activated factor VII. Can low concentrations stop bleeding in off-label indications? Thromb J 8:8
http://www.ncbi.nlm.nih.gov/pubmed/20444280
Aynaoglu G, Durdag GD, Ozmen B, and Soylemez F (2010) Successful treatment of hereditary factor VII deficiency presented for the first time with epistaxis in pregnancy: A case report. J Matern Fetal Neonatal Med
http://www.ncbi.nlm.nih.gov/pubmed/20476876
Balci YI, Karabulut A, Kabukcu S, Sari I, and Keskin A (2010) Intensive menstrual bleeding successfully treated with recombinant factor VIIa in Glanzmann thrombasthenia. Clin Appl Thromb Hemost
http://www.ncbi.nlm.nih.gov/pubmed/20460355
Bruneau JC, O'Marcaigh A, and Smith OP (2010) Gemtuzumab ozogamicin (Mylotarg(R)) upregulates tissue factor expression but not secretion of inflammatory cytokines TNF-alpha or IL-8. Leuk Res
http://www.ncbi.nlm.nih.gov/pubmed/20471678
Christersson C, Johnell M, and Siegbahn A (2010) The influence of direct thrombin inhibitors on the formation of platelet-leukocyte aggregates and tissue factor expression. Thromb Res
http://www.ncbi.nlm.nih.gov/pubmed/20451956
Chuansumrit A, Teeraratkul S, Wanichkul S, Treepongkaruna S, Sirachainan N, Pakakasama S, Nuntnarumit P, and Hongeng S (2010) Recombinant-activated factor VII for control and prevention of hemorrhage in nonhemophilic pediatric patients. Blood Coagul Fibrinolysis 21:354-362.
http://www.ncbi.nlm.nih.gov/pubmed/20449890
Cugno M, Tedeschi A, Crosti C, and Marzano AV (2009) Activation of blood coagulation in autoimmune skin disorders. Expert Rev Clin Immunol 5:605-613.
http://www.ncbi.nlm.nih.gov/pubmed/20477646
de Meise E, Azambuja D, Ayres-Silva JP, Zamboni M, Pinheiro VR, Levy RA, and Monteiro RQ (2010) Increased expression of tissue factor and protease-activated receptor-1 does not correlate with thrombosis in human lung adenocarcinoma. Braz J Med Biol Res 43:403-408.
http://www.ncbi.nlm.nih.gov/pubmed/20445954
Garnier D, Milsom C, Magnus N, Meehan B, Weitz J, Yu J, and Rak J (2010) Role of the tissue factor pathway in the biology of tumor initiating cells. Thromb Res 125 Suppl 2:S44-S50
http://www.ncbi.nlm.nih.gov/pubmed/20434004
Green D, Foiles N, Chan C, Kang J, Schreiner PJ, and Liu K (2010) An Association between clotting factor VII and carotid intima-media thickness. The CARDIA Study. Stroke
http://www.ncbi.nlm.nih.gov/pubmed/20466994
Jiang R, Wang NP, Tanaka KA, Levy JH, Guyton RA, Zhao ZQ, and Vinten-Johansen J (2010) Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-kappaB-dependent pathways. J Surg Res
http://www.ncbi.nlm.nih.gov/pubmed/20451919
Jin H, Wang DY, Mei YF, Qiu WB, Zhou Y, Wang DM, Tan XR, and Li YG (2010) Mitogen-activated protein kinases pathway is involved in physiological testosterone-induced tissue factor pathway inhibitor expression in endothelial cells. Blood Coagul Fibrinolysis
http://www.ncbi.nlm.nih.gov/pubmed/20442653
Lopaciuk S, Windyga J, Watala CW, Bykowska K, Pietrucha T, Kwiecinski H, Czlonkowska A, Kuczynska-Zardzewialy A, Jackson AA, Carew JA, and Bauer KA (2010) Polymorphisms in the factor VII gene and ischemic stroke in young adults. Blood Coagul Fibrinolysis
http://www.ncbi.nlm.nih.gov/pubmed/20453637
Magnus N, Garnier D, and Rak J (2010) Oncogenic epidermal growth factor receptor upregulates multiple elements of the tissue factor signaling pathway in human glioma cells. Blood
http://www.ncbi.nlm.nih.gov/pubmed/20462964
Nadir Y and Brenner B (2010) Heparanase procoagulant effects and inhibition by heparins. Thromb Res 125 Suppl 2:S72-S76
http://www.ncbi.nlm.nih.gov/pubmed/20434010
Ndonwi M, Tuley EA, and Broze GJ, Jr. (2010) The Kunitz-3 domain of TFPI{alpha} is required for protein S-dependent enhancement of factor Xa inhibition. Blood
http://www.ncbi.nlm.nih.gov/pubmed/20479289
Opstad TB, Eilertsen AL, Hoibraaten E, Skretting G, and Sandset PM (2010) Tissue factor pathway inhibitor polymorphisms in women with and without a history of venous thrombosis and the effects of postmenopausal hormone therapy. Blood Coagul Fibrinolysis
http://www.ncbi.nlm.nih.gov/pubmed/20453636
Opstad TB, Pettersen AA, Weiss T, Arnesen H, and Seljeflot I (2010) Gender differences of polymorphisms in the TF and TFPI genes, as related to phenotypes in patients with coronary heart disease and type-2 diabetes. Thromb J 8:7
http://www.ncbi.nlm.nih.gov/pubmed/20444258
Popescu NI, Lupu C, and Lupu F (2010) Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure. Blood
http://www.ncbi.nlm.nih.gov/pubmed/20448108
Ricker L, Al Diere R, Beckers G, Pels E, Liem A, Hendrikse F, Kijlstra A, Hemker HC, and La Heij E (2010) High subretinal fluid procoagulant activity in rhegmatogenous retinal detachment. Invest Ophthalmol Vis Sci
http://www.ncbi.nlm.nih.gov/pubmed/20435588
Ruf W, Yokota N, and Schaffner F (2010) Tissue factor in cancer progression and angiogenesis. Thromb Res 125 Suppl 2:S36-S38
http://www.ncbi.nlm.nih.gov/pubmed/20434002
Schwoppe C, Kessler T, Persigehl T, Liersch R, Hintelmann H, Dreischaluck J, Ring J, Bremer C, Heindel W, Mesters RM, and Berdel WE (2010) Tissue-factor fusion proteins induce occlusion of tumor vessels. Thromb Res 125 Suppl 2:S143-S150
http://www.ncbi.nlm.nih.gov/pubmed/20433995
Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Sfyroera G, et al. (2010) Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of E. coli sepsis. Blood
http://www.ncbi.nlm.nih.gov/pubmed/20466856
Xu Z, Xu H, Ploplis VA, and Castellino FJ (2010) Factor VII deficiency impairs cutaneous wound healing in mice. Mol Med 16:167-176.
http://www.ncbi.nlm.nih.gov/pubmed/20454518
Xu Z, Lioi J, Mu J, Kamocka MM, Liu X, Chen DZ, Rosen ED, and Alber M (2010) A multiscale model of venous thrombus formation with surface-mediated control of blood coagulation cascade. Biophys J 98:1723-1732.
http://www.ncbi.nlm.nih.gov/pubmed/20441735
Zwicker JI (2010) Predictive value of tissue factor bearing microparticles in cancer associated thrombosis. Thromb Res 125 Suppl 2:S89-S91
http://www.ncbi.nlm.nih.gov/pubmed/20434015
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ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
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