Thursday, December 7, 2017

Vol. 23, No. 23

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 23, No. 23  December 1, 2017
(The next issue will be on December 15, 2017)
_________________________________
TRIGGER is also available by RSS Feed
and BLOG.
_________________________________
UPCOMING MEETINGS EVENTS
General info on upcoming meetings of interest. (link)

ISTH also maintains a list of upcoming meetings of interest. (link)
_________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THIS LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION"

Andresen MS, Ali HO, Myklebust CF, Sandset PM, Stavik B, Iversen N, Skretting G (2017) Estrogen induced expression of tissue factor pathway inhibitor-2 in MCF7 cells involves lysine-specific demethylase 1. Mol Cell Endocrinol 443:80-88.

Carvalho LM, Ferreira CN, Soter MO, Sales MF, Rodrigues KF, Martins SR, . . . Gomes KB (2017) Microparticles: Inflammatory and haemostatic biomarkers in Polycystic Ovary Syndrome. Mol Cell Endocrinol 443:155-162.

Che SPY, Park JY, Stokol T (2017) Tissue Factor-Expressing Tumor-Derived Extracellular Vesicles Activate Quiescent Endothelial Cells via Protease-Activated Receptor-1. Front Oncol 7:261.

D'Asti E, Anderson GM, Rak J (2017) Inhibition of tissue factor signaling in breast tumour xenografts induces widespread changes in the microRNA expression profile. Biochem Biophys Res Commun 494:700-705.

Deng C, Wu D, Yang M, Chen Y, Ding H, Zhong Z, . . . Liu K (2016) The role of tissue factor and autophagy in pulmonary vascular remodeling in a rat model for chronic thromboembolic pulmonary hypertension. Respir Res 17:65.

Deng HF, Wang XL, Sun H, Xiao XZ (2017) Puerarin inhibits expression of tissue factor induced by oxidative low-density lipoprotein through activating the PI3K/Akt/eNOS pathway and inhibiting activation of ERK1/2 and NF-kappaB. Life Sci 191:115-121.

Fischer D, Bussow J, Meybohm P, Weber CF, Zacharowski K, Urbschat A, . . . Jennewein C (2017) Microparticles from stored red blood cells enhance procoagulant and proinflammatory activity. Transfusion 57:2701-2711.

Grasso S, Neumann A, Lang IM, Etscheid M, von Kockritz-Blickwede M, Kanse SM (2017) Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs). Thromb Res 161:36-42.

Hay CRM, Sharpe T, Dolan G (2017) Use of the UKHCDO Database for a postmarketing surveillance study of different doses of recombinant factor VIIa in haemophilia. Haemophilia 23:376-382.

He SW, Wang GH, Yue B, Zhou S, Zhang M (2017) TO17: A teleost antimicrobial peptide that induces degradation of bacterial nucleic acids and inhibits bacterial infection in red drum, Sciaenops ocellatus. Fish Shellfish Immunol.

Hu H, Chen X, Wang C, Jiang Y, Li J, Ying X, . . . Duan S (2017) The role of TFPI2 hypermethylation in the detection of gastric and colorectal cancer. Oncotarget 8:84054-84065.

Liu R, Ma Q, Wen A, Tian G, Li M, Wang W, Wang W (2017) Increased tissue factor expression and promoter hypomethylation in preeclampsia placentas in a Chinese population. Pregnancy Hypertens 10:90-95.

Sciallero C, Daglio E, Trucco A (2016) In vivo quantification of ultrasound targeted microbubbles to enhance cancer assessment. Contrast Media Mol Imaging 11:313-318.

Shashar M, Belghasem ME, Matsuura S, Walker J, Richards S, Alousi F, . . . Chitalia VC (2017) Targeting STUB1-tissue factor axis normalizes hyperthrombotic uremic phenotype without increasing bleeding risk. Sci Transl Med 9.

Staszewski J, Piusinska-Macoch R, Brodacki B, Skrobowska E, Stepien A (2017) Association between hemostatic markers, serum lipid fractions and progression of cerebral small vessel disease: A 2-year follow-up study. Neurol Neurochir Pol.

van den Boogaard FE, Hofstra JJ, Brands X, Levi MM, Roelofs JJ, Zaat SA, . . . Schultz MJ (2017) Nebulized Recombinant Human Tissue Factor Pathway Inhibitor Attenuates Coagulation and Exerts Modest Anti-inflammatory Effects in Rat Models of Lung Injury. J Aerosol Med Pulm Drug Deliv 30:91-99.

Wannamethee SG, Whincup PH, Papacosta O, Lennon L, Lowe GD (2017) Associations between blood coagulation markers, NT-proBNP and risk of incident heart failure in older men: The British Regional Heart Study. Int J Cardiol 230:567-571.

Zeerleder S (2017) Factor VII-Activating Protease: Hemostatic Protein or Immune Regulator? Semin Thromb Hemost.
_________________________________
ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: James Morrissey, Dept. of Biological Chemistry, University of Michigan Medical School, 4301E MSRB III (Box 0600), 1150 West Medical Center Dr., Ann Arbor, MI 48109-5606, USA.

DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
_________________________________

Monday, November 6, 2017

Vol. 23, No. 21

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 23, No. 21  November 3, 2017
(The next issue will be on December 1, 2017)
_________________________________
TRIGGER is also available by RSS Feed
and BLOG.
_________________________________
ANNOUNCEMENTS

Kenneth M. Brinkhous Young Investigator Prize in Thrombosis

This award, sponsored by the Council on Arteriosclerosis, Thrombosis and Vascular Biology (ATVB) of the American Heart Association (AHA), recognizes outstanding endeavors by new investigators in fundamental and applied research in Thrombosis, including the mechanism, detection, treatment, and prevention of thrombotic disorders.

Applicants must be an AHA member. Applicants must be early-career (post-doctoral associated, fellows, or pre-tenured junior faculty).

Applicants must submit an abstract describing new, unpublished work in the field of thrombosis to the ATVB|PVD 2018 meeting (now called Vascular Discovery), and a single manuscript, either unpublished or accepted for publication after January 1, 2017, is required as part of the application. The finalists will present their research during a special session at the ATVB|PVD 2018 Scientific Sessions in San Francisco, California. The first-prize winner will receive an engraved plaque and $1000, plus a $500 stipend to defray travel costs. Other finalists will each receive a plaque and a $500 travel stipend. Detailed information on how to apply can be found at this link:

Questions may be directed by email to Neyssa Shockley, Project Coordinator.
_________________________________
UPCOMING MEETINGS EVENTS
Here are some meetings of interest during the first half of 2018:

March
THSNA (Thrombosis & Hemostasis Societies of North America) meeting March 8-10, 2018 in San Diego, CA.
Abstract deadline: November 17, 2017 (link)

April
9th Symposium on Hemostasis: Advances in the Clinical and Basic Sciences of Coagulation April 12-14, 2018 in Chapel Hill, NC.
Abstract deadline: February 25, 2018 (link)

May
ATVB|PVD: Arteriosclerosis, Thrombosis and Vascular Biology |
Peripheral Vascular Disease Scientific Sessions, May 9-12, 2018 in San Francisco, CA.
Their web site says "More details coming soon" (link)

July
ISTH-SSC meeting July 18-21, 2018 in Dublin, Ireland.
Abstract deadline: February 1, 2018 (link)

Hemostasis Gordon Research Conference (GRC) July 29 - August 3, 2018 in Waterville Valley, New Hampshire.
Although the registration deadline is officially listed as a few weeks before the conference starts, you should apply quite early to have a chance to get in, as the meeting is usually over-subscribed. (link)

This GRC is immediately preceded by Hemostasis GRS for trainees only, July 28-29. (link)

    * * *    * * *    * * *    * * *
General info on upcoming meetings of interest. (link)

ISTH also maintains a list of upcoming meetings of interest. (link)
_________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THIS LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION"


































_________________________________
ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: James Morrissey, Dept. of Biological Chemistry, University of Michigan Medical School, 4301E MSRB III (Box 0600), 1150 West Medical Center Dr., Ann Arbor, MI 48109-5606, USA.

DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
_________________________________

Thursday, October 19, 2017

Vol. 23, No. 20

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 23, No. 20  October 15, 2017
(The next issue will be on November 2, 2017)
_________________________________
TRIGGER is also available by RSS Feed
and BLOG.
_________________________________
UPCOMING MEETINGS EVENTS
The 4th Biennial Summit of the Thrombosis & Hemostasis Societies of North America (THSNA) will be held on March 8-10, 2018 in San Diego, California. There will be a THSNA Pre-Summit Workshop on March 7. The deadline for early registration (lower registration fee) is October 31, 2017. The abstract deadline is November 17, 2017. For more information, click here.

For general info on upcoming meetings of interest, click here.

ISTH also maintains a list of upcoming meetings of interest: Click here.
_________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THIS LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION"

Aharon A, Sabbah A, Ben-Shaul S, Berkovich H, Loven D, Brenner B, Bar-Sela G (2017) Chemotherapy administration to breast cancer patients affects extracellular vesicles thrombogenicity and function. Oncotarget 8:63265-63280.

Akhmedov A, Camici GG, Reiner MF, Bonetti NR, Costantino S, Holy EW, . . . Luscher TF (2017) Endothelial LOX-1 activation differentially regulates arterial thrombus formation depending on oxLDL levels: role of the Oct-1/SIRT1 and ERK1/2 pathways. Cardiovasc Res 113:498-507.

Bozinovski J (2017) Take me to your bleeder: Recombinant factor VIIa-finding its way in cardiac surgery. J Thorac Cardiovasc Surg.

Bratseth V, Byrkjeland R, Njerve IU, Solheim S, Arnesen H, Seljeflot I (2017) Procoagulant activity in patients with combined type 2 diabetes and coronary artery disease: No effects of long-term exercise training. Diab Vasc Dis Res 14:144-151.

Bustamante A, Diaz-Fernandez B, Giralt D, Boned S, Pagola J, Molina CA, . . . Montaner J (2016) Factor seven activating protease (FSAP) predicts response to intravenous thrombolysis in acute ischemic stroke. Int J Stroke 11:646-655.

Chan MK, Cooper JD, Heilmann-Heimbach S, Frank J, Witt SH, Nothen MM, . . . Bahn S (2017) Associations between SNPs and immune-related circulating proteins in schizophrenia. Sci Rep 7:12586.

Ducore J, Lawrence JB, Simpson M, Boggio L, Bellon A, Burggraaf J, . . . Wang M (2017) Safety and dose-dependency of eptacog beta (activated) in a dose escalation study of non-bleeding congenital haemophilia A or B patients, with or without inhibitors. Haemophilia.

Ersayin A, Thomas A, Seyve L, Thielens N, Castellan M, Marlu R, . . . Dagher MC (2017) Catalytically inactive Gla-domainless factor Xa binds to TFPI and restores ex vivo coagulation in hemophilia plasma. Haematologica.

Fujii E, Watanabe K, Nishihara K, Suzuki M, Kato A (2017) Hazard characterization of an anti-human tissue factor antibody by combining results of tissue cross-reactivity studies and distribution of hemorrhagic lesions in monkey toxicity studies. Regul Toxicol Pharmacol 90:289-296.

Granger V, Faille D, Marani V, Noel B, Gallais Y, Szely N, . . . de Chaisemartin L (2017) Human blood monocytes are able to form extracellular traps. J Leukoc Biol 102:775-781.

He JP, Feng JX (2017) Two-incision laparoscopic appendectomy for a severe hemophilia A child patient with coagulation factor VII deficiency: Case report and review of literature. Medicine
(Baltimore) 96:e8197.

Iotzova-Weiss G, Freiberger SN, Johansen P, Kamarachev J, Guenova E, Dziunycz PJ, . . . Hofbauer GFL (2017) TLR4 as a negative regulator of keratinocyte proliferation. PLoS One 12:e0185668.

Nogami K (2017) Future prospects of hemostatic treatment for hemophilia patients. Rinsho Ketsueki 58:2074-2080.

Papalardo E, Romay-Penabad Z, Willis R, Christadoss P, Carrera-Marin AL, Reyes-Maldonado E, . . . Gonzalez EB (2017) Major Histocompatibility Complex Class II Alleles Influence Induction of Pathogenic Antiphospholipid Antibodies in a Mouse Model of Thrombosis. Arthritis Rheumatol 69:2052-2061.

Passarelli PC, Pasquantonio G, D'Addona A (2017) Management of Surgical Third Lower Molar Extraction and Postoperative Progress in Patients With Factor VII Deficiency: A Clinical Protocol and Focus on This Rare Pathologic Entity. J Oral Maxillofac Surg 75:2070 e2071-2070 e2074.

Pryzdial ELG (2017) Maestro tissue factor reaches new hEIGHT. Blood 130:1604-1605.

Qadir H, Rashid A, Adil SN (2017) Cerebral Venous Sinus Thrombosis in a Patient with Undiagnosed Factor VII Deficiency. J Coll Physicians Surg Pak 27:S86-S88.

Reiner MF, Akhmedov A, Stivala S, Keller S, Gaul DS, Bonetti NR, . . . Beer JH (2017) Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression. Cardiovasc Res 113:61-69.

Repetto O, De Re V (2017) Coagulation and fibrinolysis in gastric cancer. Ann N Y Acad Sci 1404:27-48.

Sakuma M, Tanaka A, Kotooka N, Hikichi Y, Toyoda S, Abe S, . . . Inoue T (2017) Myeloid-related protein-8/14 in acute coronary syndrome. Int J Cardiol.

Schlagenhauf A, Haidl H, Pohl S, Weiss EC, Leschnik B, Gallistl S, Muntean W (2017) Polyphosphate in Neonates: Less Shedding from Platelets and Divergent Prothrombotic Capacity Due to Lower TFPI Levels. Front Physiol 8:586.

Yanase Y, Takahagi S, Hide M (2017) Chronic spontaneous urticaria and the extrinsic coagulation system. Allergol Int.

Zhalyalov AS, Panteleev MA, Gracheva MA, Ataullakhanov FI, Shibeko AM (2017) Co-ordinated spatial propagation of blood plasma clotting and fibrinolytic fronts. PLoS One 12:e0180668.

Zindovic I, Sjogren J, Ahlsson A, Bjursten H, Fuglsang S, Geirsson A, . . . Nozohoor S (2017) Recombinant factor VIIa use in acute type A aortic dissection repair: A multicenter propensity-score-matched report from the Nordic Consortium for Acute Type A Aortic Dissection. J Thorac Cardiovasc Surg.
_________________________________
ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: James Morrissey, Dept. of Biological Chemistry, University of Michigan Medical School, 4301E MSRB III (Box 0600), 1150 West Medical Center Dr., Ann Arbor, MI 48109-5606, USA.

DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
_________________________________

Monday, October 2, 2017

Vol. 23, No. 19

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 23, No. 19  October 1, 2017
(The next issue will be on October 18, 2017)
_________________________________
TRIGGER is also available by RSS Feed
and BLOG.
_________________________________
UPCOMING MEETINGS EVENTS
For general info on upcoming meetings of interest, click here.

ISTH also maintains a list of upcoming meetings of interest: Click here.
_________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":

Arderiu G, Espinosa S, Pena E, Aledo R, Badimon L (2016) PAR2-SMAD3 in microvascular endothelial cells is indispensable for vascular stability via tissue factor signaling. J Mol Cell Biol 8:255-270.

Barska K, Kwiatkowska W, Knysz B, Arczynska K, Karczewski M, Witkiewicz W (2017) The role of the tissue factor and its inhibitor in the development of subclinical atherosclerosis in people living with HIV. PLoS One 12:e0181533.

Bern MM (2017) Extracellular vesicles: how they interact with endothelium, potentially contributing to metastatic cancer cell implants. Clin Transl Med 6:33.

Calmette L, Martin AC, Le Bonniec B, Zlotnik D, Gouin-Thibault I, Bachelot-Loza C, . . . Godier A (2017) Ticagrelor reversal: in vitro assessment of four haemostatic agents. J Clin Pathol 70:733-739.

Chai-Adisaksopha C, Nevitt SJ, Simpson ML, Janbain M, Konkle BA
(2017) Bypassing agent prophylaxis in people with hemophilia A or B with inhibitors. Cochrane Database Syst Rev 9:CD011441.

Chan JL, Singh AK, Corcoran PC, Thomas ML, Lewis BG, Ayares DL, . . .
Mohiuddin MM (2017) Encouraging experience using multi-transgenic xenografts in a pig-to-baboon cardiac xenotransplantation model.
Xenotransplantation.

Chandrashekar V (2017) Simplified Method for Local Correction of System International Normalized Ratio. Lab Med 48:244-248.

Dambrauskiene R, Gerbutavicius R, Ugenskiene R, Jankauskaite R, Savukaityte A, Simoliuniene R, . . . Juozaityte E (2017) Genetic Polymorphisms of Hemostatic Factors and Thrombotic Risk in Non BCR-ABL Myeloproliferative Neoplasms: A Pilot Study. Balkan J Med Genet 20:35-42.

De Paula VS, Silva FHS, Francischetti IMB, Monteiro RQ, Valente AP
(2017) Recombinant expression of Ixolaris, a Kunitz-type inhibitor from the tick salivary gland, for NMR studies. Protein Expr Purif 139:49-56.

de Sousa Bomfim A, de Freitas MCC, Covas DT, de Sousa Russo EM (2018) Human Cells as Platform to Produce Gamma-Carboxylated Proteins.
Methods Mol Biol 1674:49-61.

Ettelaie C, Collier MEW, Featherby S, Greenman J, Maraveyas A (2017) Peptidyl-prolyl isomerase 1 (Pin1) preserves the phosphorylation state of tissue factor and prolongs its release within microvesicles.
Biochim Biophys Acta.

Falanga A, Russo L, Milesi V, Vignoli A (2017) Mechanisms and risk factors of thrombosis in cancer. Crit Rev Oncol Hematol 118:79-83.

Flannery AH, Pandya K, Laine ME, Almeter PJ, Flynn JD (2017) Managing the Rising Costs and High Drug Expenditures in Critical Care Pharmacy Practice. Pharmacotherapy 37:54-64.

Gao S, Lin Z, Li C, Wang Y, Yang L, Zou B, . . . Liu G (2017) TFPI2AS1, a novel lncRNA that inhibits cell proliferation and migration in lung cancer. Cell Cycle:1-10.

Grandone E, Chinni E, Villani M, Scianname N, Tiscia GL, Favuzzi G, .
. . Margaglione M (2016) Modulation of factors involved in placental haemostasis and angiogenesis by low-molecular-weight-heparins. Arch Gynecol Obstet 294:1323-1329.

Granovski V, Freitas MCC, Abreu-Neto MS, Covas DT (2018) Purification and Autoactivation Method for Recombinant Coagulation Factor VII.
Methods Mol Biol 1674:221-226.

Gussregen S, Matter H, Hessler G, Lionta E, Heil J, Kast SM (2017) Thermodynamic Characterization of Hydration Sites from Integral Equation-Derived Free Energy Densities: Application to Protein Binding Sites and Ligand Series. J Chem Inf Model 57:1652-1666.

Huang J, Tian R, Yang Y, Jiang R, Dai J, Tang L, Zhang L (2017) The
SIRT1 inhibitor EX-527 suppresses mTOR activation and alleviates acute lung injury in mice with endotoxiemia. Innate Immun:1753425917733531.

Jaitly V, Klein K, Tint H, Chen A, Allison P, Akkanti B, . . .
Castillo B (2017) Intra-Pericardial Use of Recombinant Factor VIIa in a Patient With Acute Hemorrhagic Pericardial Effusion Following Transcutaneous Aortic Valve Replacement-A Case Report. Lab Med 48:262-265.

Kassem M, Niazi ZR, Abbas M, El Habhab A, Kreutter G, Khemais-Benkhiat S, . . . Kessler L (2017) Senescence of Pancreas in Middle-Aged Rats with Normal Vascular Function. Ann Transplant 22:177-186.

Keshava S, Sundaram J, Rajulapati A, Esmon C, Pendurthi U, Rao LVM
(2017) Factor VIIa interaction with EPCR modulates the hemostatic effect of rFVIIa in hemophilia therapy: Mode of its action. Blood Adv 1:1206-1214.

Kotla S, Singh NK, Kirchhofer D, Rao GN (2017) Heterodimers of the transcriptional factors NFATc3 and FosB mediate tissue factor expression for 15(S)-hydroxyeicosatetraenoic acid-induced monocyte trafficking. J Biol Chem 292:14885-14901.

Kovalenko TA, Panteleev MA, Sveshnikova AN (2017) Substrate delivery mechanism and the role of membrane curvature in factor X activation by extrinsic tenase. J Theor Biol 435:125-133.

Lohrmann GM, Atwal D, Augoustides JG, Askar W, Patel PA, Ghadimi K, .
. . Ramakrishna H (2016) Reversal Agents for the New Generation of Oral Anticoagulants: Implications for the Perioperative Physician. J Cardiothorac Vasc Anesth 30:823-830.

Matus V, Valenzuela JG, Hidalgo P, Pozo LM, Panes O, Wozniak A, . . .
Saez CG (2017) Human platelet interaction with E. coli O111 promotes tissue-factor-dependent procoagulant activity, involving Toll like receptor 4. PLoS One 12:e0185431.

Takashima H, Tsuji AB, Saga T, Yasunaga M, Koga Y, Kuroda JI, . . .
Matsumura Y (2017) Molecular imaging using an anti-human tissue factor monoclonal antibody in an orthotopic glioma xenograft model.
Sci Rep 7:12341.

Tong M, Wang J, Ji Y, Chen X, Wang J, Wang S, . . . Watanabe E (2017) Effect of eicosapentaenoic acid and pitavastatin on electrophysiology and anticoagulant gene expression in mice with rapid atrial pacing.
Exp Ther Med 14:2310-2316.

Unruh D, Schwarze SR, Khoury L, Thomas C, Wu M, Chen L, . . .
Horbinski C (2016) Mutant IDH1 and thrombosis in gliomas. Acta Neuropathol 132:917-930.

Yasunaga M, Manabe S, Tsuji A, Furuta M, Ogata K, Koga Y, . . .
Matsumura Y (2017) Development of Antibody-Drug Conjugates Using DDS and Molecular Imaging. Bioengineering (Basel) 4.

Yuan Q, Zhang D, Wu S, Yu J, Yu L, Sun Y, . . . Hu J (2017) FVIIa prevents the progressive hemorrhaging of a brain contusion by protecting microvessels via formation of the TF-FVIIa-FXa complex.
Neuroscience 348:114-125.

Zhang X, Li Q, Zhao H, Ma L, Meng T, Qian J, . . . Yu K (2017) Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma. Oncotarget 8:59086-59102.

Zhu S, Lu Y, Sinno T, Diamond SL (2016) Dynamics of Thrombin Generation and Flux from Clots during Whole Human Blood Flow over Collagen/Tissue Factor Surfaces. J Biol Chem 291:23027-23035.

_________________________________
ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: James Morrissey, Dept. of Biological Chemistry, University of Michigan Medical School, 4301E MSRB III (Box 0600), 1150 West Medical Center Dr., Ann Arbor, MI 48109-5606, USA.

DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
_________________________________