Monday, July 2, 2012

Vol. 18, No. 13

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 18, No. 13  July 2, 2012
(The next issue will be on July 16, 2012)
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PRODUCT ANNOUNCEMENT
Diagnostica Stago Offers Three Factor VII Detection Methods.
June 15, 2012, Parsippany, NJ, USA - Diagnostica Stago, Inc. announces products to suit a variety of clinical research needs for factor VII (FVII).
  • Staclot® VIIa-rTF (catalog #00281) is a kit for plasma analysis of circulating FVIIa using a clotting method.  This unique product is a tool for research studies where the determination of FVIIa levels may be useful due to the fact that it reflects coagulation activation as a result of in vivo FVIIa production.
  • Asserachrom® VII:Ag (catalog #00241) is an enzyme-linked immunosorbent assay (ELISA) that determines the antigen level of factor VII in plasma samples.
  • Asserachrom® VIIa-AT (catalog #00491) is a new kit for the analysis of plasma circulating factor VIIa-Antithrombin (FVIIa-AT) complex levels by the ELISA method, and can be run on any plate reader reporting absorbance at 450 nm.  This first of its kind product is useful for examination of FVIIa-AT levels, which has been recognized in the literature as a surrogate marker for the extent of tissue factor (TF) exposure to plasma as a result of coagulation activation in prothrombotic disease states such as arterial and venous thrombosis.  Unlike the FVIIa-TFPI complex, which stays bound to the endothelium, FVIIa-AT is present in the blood upon physiological coagulation activation, making it a useful surrogate marker for this phenomenon.    
All three methods described are for research use only (not for use in diagnostic procedures).

Contact:
Paul Riley, PhD, Manager, Research Use Products
Diagnostica Stago, Inc.
(973) 631-1200 x4238
paul DOT riley AT stago-us DOT com

Web links:
www.stago-us.com

http://www.stago-us.com/nc/products-services/catalog/research-products/selection/type-research-products/group/research-kits-2/

DISCLAIMER:  Commercial product announcements appearing in TRIGGER are provided "as is" for informational purposes only.  The editors of TRIGGER have not necessarily evaluated any materials from commercial suppliers described in this newsletter or on its web sites, and we certainly are not endorsing any specific suppliers or products.  Furthermore, the editors receive no revenues from any source in the course of publishing TRIGGER.
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PAPERS IN PRESS
None Submitted for this issue.
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RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1z3QgAX-nJw_r6xRhcq48Dc/

Abbate R, Cioni G, Ricci I, Miranda M, Gori AM (2012) Thrombosis and acute coronary syndrome. Thromb Res 129:235-240.
http://www.ncbi.nlm.nih.gov/pubmed/22281070

Basavaraj MG, Olsen JO, Osterud B, Hansen JB (2012) Differential ability of tissue factor antibody clones on detection of tissue factor in blood cells and microparticles. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22728024

Basavaraj MG, Osterud B, Hansen JB (2012) Influence of different anticoagulants on monocyte procoagulant functions and monocyte-platelet aggregates formation. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/22712695

Bhindi R, Fahmy RG, McMahon AC, Khachigian LM, Lowe HC (2012) Intracoronary delivery of DNAzymes targeting human EGR-1 reduces infarct size following myocardial ischaemia reperfusion. J Pathol 227:157-164.
http://www.ncbi.nlm.nih.gov/pubmed/22344601

Camera M, Brambilla M, Facchinetti L, Canzano P, Spirito R, Rossetti L, . . . Tremoli E (2012) Tissue factor and atherosclerosis: not only vessel wall-derived TF, but also platelet-associated TF. Thromb Res 129:279-284.
http://www.ncbi.nlm.nih.gov/pubmed/22178579

Cerletti C, Tamburrelli C, Izzi B, Gianfagna F, de Gaetano G (2012) Platelet-leukocyte interactions in thrombosis. Thromb Res 129:263-266.
http://www.ncbi.nlm.nih.gov/pubmed/22075180

Chan KC, Pen PJ, Yin MC (2012) Anticoagulatory and antiinflammatory effects of astaxanthin in diabetic rats. J Food Sci 77:H76-80.
http://www.ncbi.nlm.nih.gov/pubmed/22309505

Chen X, Lv H, Ye M, Wang S, Ni E, Zeng F, . . . Yan J (2012) Novel superparamagnetic iron oxide nanoparticles for tumor embolization application: preparation, characterization and double targeting. Int J Pharm 426:248-255.
http://www.ncbi.nlm.nih.gov/pubmed/22310463

Cirillo P, Di Palma V, Maresca F, Pacifico F, Ziviello F, Bevilacqua M, . . . Chiariello M (2012) The adipokine visfatin induces tissue factor expression in human coronary artery endothelial cells: Another piece in the adipokines puzzle. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22726553

Cooper DK, Ekser B, Burlak C, Ezzelarab M, Hara H, Paris L, . . . Pierson RN, 3rd (2012) Clinical lung xenotransplantation - what donor genetic modifications may be necessary? Xenotransplantation 19:144-158.
http://www.ncbi.nlm.nih.gov/pubmed/22702466

Corrales-Rodriguez L, Blais N (2012) Lung cancer associated venous thromboembolic disease: a comprehensive review. Lung Cancer 75:1-8.
http://www.ncbi.nlm.nih.gov/pubmed/21820753

Donati MB, Lorenzet R (2012) Thrombosis and cancer: 40 years of research. Thromb Res 129:348-352.
http://www.ncbi.nlm.nih.gov/pubmed/22264938

Fu Y, Zhao Y, Liu Y, Zhu Y, Chi J, Hu J, . . . Yin X (2012) Adenovirus-mediated tissue factor pathway inhibitor gene transfer induces apoptosis by blocking the phosphorylation of JAK-2/STAT-3 pathway in vascular smooth muscle cells. Cell Signal.
http://www.ncbi.nlm.nih.gov/pubmed/22709828

Goodnough LT (2012) A Reappraisal of Plasma, Prothrombin Complex Concentrates, and Recombinant Factor VIIa in Patient Blood Management. Crit Care Clin 28:413-426.
http://www.ncbi.nlm.nih.gov/pubmed/22713615

Haque A, Arnaud F, Teranishi K, Okada T, Kim B, Moon-Massat PF, . . . Scultetus AH (2012) Pre-hospital resuscitation with HBOC-201 and rFVIIa compared to HBOC-201 alone in uncontrolled hemorrhagic shock in swine. Artif Cells Blood Substit Immobil Biotechnol 40:44-55.
http://www.ncbi.nlm.nih.gov/pubmed/21806503

Harkouk H, Chakib Rahmoune F, Benhamou D (2012) [Postpartum haemorrhage and factor VII deficiency]. Ann Fr Anesth Reanim 31:169-171.
http://www.ncbi.nlm.nih.gov/pubmed/22197042

Hellum M, Ovstebo R, Troseid AM, Berg JP, Brandtzaeg P, Henriksson CE (2012) Microparticle-associated tissue factor activity measured with the Zymuphen MP-TF kit and the calibrated automated thrombogram assay. Blood Coagul Fibrinolysis.
http://www.ncbi.nlm.nih.gov/pubmed/22732249

Joseph B, Amini A, Friese RS, Houdek M, Hays D, Kulvatunyou N, . . . Rhee P (2012) Factor IX complex for the correction of traumatic coagulopathy. J Trauma Acute Care Surg 72:828-834.
http://www.ncbi.nlm.nih.gov/pubmed/22491593

Kathuria A, Priya N, Chand K, Singh P, Gupta A, Jalal S, . . . Sharma SK (2012) Substrate specificity of acetoxy derivatives of coumarins and quinolones towards Calreticulin mediated transacetylation: investigations on antiplatelet function. Bioorg Med Chem 20:1624-1638.
http://www.ncbi.nlm.nih.gov/pubmed/22264757

Kotschy M, Witkiewicz W, Grendziak R, Dubis J, Zapotoczny N, Kotschy D (2012) [Selected clotting factors in blood of patients with abdominal aortic aneurysms.]. Kardiol Pol 70:574-579.
http://www.ncbi.nlm.nih.gov/pubmed/22718374

Krysiak R, Okopien B (2012) Hemostatic Effects of Metformin in Simvastatin-Treated Volunteers with Impaired Fasting Glucose. Basic Clin Pharmacol Toxicol.
http://www.ncbi.nlm.nih.gov/pubmed/22716204

Lee KG, Lee H, Ha JM, Lee YK, Kang HJ, Park CG, Kim SJ (2012) Increased human tumor necrosis factor-alpha levels induce procoagulant change in porcine endothelial cells in vitro. Xenotransplantation 19:186-195.
http://www.ncbi.nlm.nih.gov/pubmed/22702470

Lelakowski J, Domagala TB, Rydlewska A, Januszek R, Kotula Horowitz K, Majewski J, . . . Musial J (2012) Effect of selected prothrombotic and proinflammatory factors on the incidence of venous thrombosis after pacemaker implantation. Kardiol Pol 70:260-267.
http://www.ncbi.nlm.nih.gov/pubmed/22430407

Liu ML, Williams KJ (2012) Microvesicles: potential markers and mediators of endothelial dysfunction. Curr Opin Endocrinol Diabetes Obes 19:121-127.
http://www.ncbi.nlm.nih.gov/pubmed/22248645

Lorenzet R, Napoleone E, Cutrone A, Donati MB (2012) Thrombosis and obesity: cellular bases. Thromb Res 129:285-289.
http://www.ncbi.nlm.nih.gov/pubmed/22078462

Mannam VK, Lewis RE, Cruse JM (2012) The fate of renal allografts hinges on responses of the microvascular endothelium. Exp Mol Pathol.
http://www.ncbi.nlm.nih.gov/pubmed/22710034

Martinez O, Leung LW, Basler CF (2012) The role of antigen-presenting cells in filoviral hemorrhagic fever: gaps in current knowledge. Antiviral Res 93:416-428.
http://www.ncbi.nlm.nih.gov/pubmed/22333482

Ndonwi M, Girard TJ, Broze GJ, Jr. (2012) The carboxy-terminus of TFPIalpha is required for its interaction with factor V and Va. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/22738072

Nosari A, Caimi TM, Zilioli V, Molteni A, Mancini V, Morra E (2012) Cerebral hemorrhage treated with NovoSeven in acute promyelocytic leukemia. Leuk Lymphoma 53:160-161.
http://www.ncbi.nlm.nih.gov/pubmed/21780994

Ogasawara S, Daddona JL, Trimpert J, Stokol T (2012) Effect of recombinant canine interleukin-6 and interleukin-8 on tissue factor procoagulant activity in canine peripheral blood mononuclear cells and purified canine monocytes. Vet Clin Pathol.
http://www.ncbi.nlm.nih.gov/pubmed/22724392

Okuda M, Taniguchi T, Takamiya O (2012) Properties of a recombinant bovine tissue factor expressed by Silkworm pupae and its performance as an Owren-type prothrombin time reagent for warfarin monitoring. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22698434

Osterud B (2012) Tissue factor/TFPI and blood cells. Thromb Res 129:274-278.
http://www.ncbi.nlm.nih.gov/pubmed/22197177

Palkovits J, Novacek G, Kollars M, Hron G, Osterode W, Quehenberger P, . . . Weltermann A (2012) Tissue factor exposing microparticles in inflammatory bowel disease. J Crohns Colitis.
http://www.ncbi.nlm.nih.gov/pubmed/22705067

Palojarvi A, Andersson S, Siitonen S, Janer C, Petaja J (2012) High tissue factor in lungs and plasma associates with respiratory morbidity in preterm infants. Acta Paediatr 101:403-409.
http://www.ncbi.nlm.nih.gov/pubmed/22107344

Seligsohn U (2012) Treatment of inherited platelet disorders. Haemophilia 18 Suppl 4:161-165.
http://www.ncbi.nlm.nih.gov/pubmed/22726101

Wafaisade A, Lefering R, Maegele M, Helm P, Braun M, Paffrath T, Bouillon B (2012) [Recombinant factor VIIa for the treatment of exsanguinating trauma patients : A matched-pair analysis from the Trauma Registry of the German Society for Trauma Surgery.]. Unfallchirurg.
http://www.ncbi.nlm.nih.gov/pubmed/22699315

Wafaisade A, Lefering R, Maegele M, Lendemans S, Flohe S, Hussmann B, . . . Bouillon B (2012) Coagulation management of bleeding trauma patients is changing in German trauma centers: an analysis from the trauma registry of the German Society for Trauma Surgery. J Trauma Acute Care Surg 72:936-942.
http://www.ncbi.nlm.nih.gov/pubmed/22491608

Weber CF (2012) [Modern coagulation management reduces the transfusion rate of allogenic blood products]. Anasthesiol Intensivmed Notfallmed Schmerzther 47:418-425.
http://www.ncbi.nlm.nih.gov/pubmed/22744856

Wunderink RG, Mandell L (2012) Adjunctive therapy in community-acquired pneumonia. Semin Respir Crit Care Med 33:311-318.
http://www.ncbi.nlm.nih.gov/pubmed/22718217

Yu Q, Yan J, Wang S, Ji L, Ding K, Vella C, . . . Hu Z (2012) Anti-angiogenic Effects of GFP08, an Agaran-type Polysaccharide Isolated from Grateloupia filicina. Glycobiology.
http://www.ncbi.nlm.nih.gov/pubmed/22707571

Zhou ZY, Hay JW (2012) Efficacy of bypassing agents in patients with hemophilia and inhibitors: a systematic review and meta-analysis. Clin Ther 34:434-445.
http://www.ncbi.nlm.nih.gov/pubmed/22285208
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ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.

DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
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