TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 19, No. 6 March 15, 2013
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TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
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PRODUCT ANNOUNCEMENT
Polyphosphate
Given that commercial sources of long-chain polyphosphate (the type that is best for triggering the contact pathway of blood clotting) have dried up, we decided to make this material available for purchase through the company, KeraFAST. (Full disclosure: my lab receives a portion of the purchase price of polyphosphate from this company.) KeraFAST is currently selling water-soluble long-chain polyphosphate, but they may add more polyphosphate products in the future, such as medium-chain polyphosphate and possibly biotinylated polyphosphate.
For more information:
http://www.kerafast.com/p-1183-polyphosphate-high-mw-p700.aspx
-Jim Morrissey
DISCLAIMER: Commercial product announcements appearing in TRIGGER are provided "as is" for informational purposes only. The editors of TRIGGER have not necessarily evaluated any materials from commercial suppliers described in this newsletter or on its web sites, and we certainly are not endorsing any specific suppliers or products. Furthermore, the editors receive no revenues from any source in the course of publishing TRIGGER.
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UPCOMING MEETINGS & EVENTS
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 19, No. 6 March 15, 2013
(The next issue will be on April 1, 2013)
TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________
PRODUCT ANNOUNCEMENT
Polyphosphate
Given that commercial sources of long-chain polyphosphate (the type that is best for triggering the contact pathway of blood clotting) have dried up, we decided to make this material available for purchase through the company, KeraFAST. (Full disclosure: my lab receives a portion of the purchase price of polyphosphate from this company.) KeraFAST is currently selling water-soluble long-chain polyphosphate, but they may add more polyphosphate products in the future, such as medium-chain polyphosphate and possibly biotinylated polyphosphate.
For more information:
http://www.kerafast.com/p-1183-polyphosphate-high-mw-p700.aspx
-Jim Morrissey
DISCLAIMER: Commercial product announcements appearing in TRIGGER are provided "as is" for informational purposes only. The editors of TRIGGER have not necessarily evaluated any materials from commercial suppliers described in this newsletter or on its web sites, and we certainly are not endorsing any specific suppliers or products. Furthermore, the editors receive no revenues from any source in the course of publishing TRIGGER.
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UPCOMING MEETINGS & EVENTS
General info on upcoming meetings:
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PAPERS IN PRESS
None Submitted for this issue.
PAPERS IN PRESS
None Submitted for this issue.
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RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
Abdelwahab M, Khaddah N (2012) Rare coagulation disorders: a study of 70 cases in the Egyptian population. Haemophilia 18:e386-388.
Brekke OL, Waage C, Christiansen D, Fure H, Qu H, Lambris JD, . . . Mollnes TE (2013) The effects of selective complement and CD14 inhibition on the E. coli-induced tissue factor mRNA upregulation, monocyte tissue factor expression, and tissue factor functional activity in human whole blood. Adv Exp Med Biol 735:123-136.
Christersson C, Johnell M, Siegbahn A (2013) Evaluation of microparticles in whole blood by multicolour flow cytometry assay. Scand J Clin Lab Invest.
Dargaud Y, Simpson H, Chevalier Y, Scoazec JY, Hot A, Guyen O, . . . Negrier C (2012) The potential role of synovial thrombomodulin in the pathophysiology of joint bleeds in haemophilia. Haemophilia 18:818-823.
Drozdowska J (2012) [Tissue factor in endothelial cells--its structure and function according to the current literature]. Postepy Biochem 58:273-280.
Fleitas T, Martinez-Sales V, Vila V, Reganon E, Mesado D, Martin M, . . . Reynes G (2013) VEGF and TSP1 levels correlate with prognosis in advanced non-small cell lung cancer. Clin Transl Oncol.
Fries D (2013) The early use of fibrinogen, prothrombin complex concentrate, and recombinant-activated factor VIIa in massive bleeding. Transfusion 53 Suppl 1:91S-95S.
Frotscher B, Toussaint-Hacquard M, Fouyssac F, Devignes J, Lecompte T, Briquel ME (2012) Severe factor V deficiency in two brothers with different clinical presentations. Haemophilia 18:e383-385.
Fu WJ, Zheng L, Wang Q, Deng RT, Ye CQ, Wang SB, . . . Tang HH (2011) [Urinary level of tissue factor and its procoagulant activity in patients with type 2 diabetes]. Nan Fang Yi Ke Da Xue Xue Bao 31:878-881.
Goel A, Nair SC, Viswabandya A, Masilamani VP, Rao SV, George A, . . . Chandy G (2013) Preliminary experience with use of recombinant activated factor VII to control postpartum hemorrhage in acute fatty liver of pregnancy and other pregnancy-related liver disorders. Indian J Gastroenterol.
Huang ZJ, Wang R, Liu ZZ, Wang SY, Yan JH, Luo Q (2012) [Humanized monoclonal antibody TNT-3-mediated truncated tissue factor for the treatment of H22 hepatoma-bearing mice]. Zhonghua Zhong Liu Za Zhi 34:249-253.
Jayaraman M, Ansell SM, Mui BL, Tam YK, Chen J, Du X, . . . Hope MJ (2012) Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo. Angew Chem Int Ed Engl 51:8529-8533.
Kato J, Okamoto T, Motoyama H, Uchiyama R, Kirchhofer D, Van Rooijen N, . . . Tsutsui H (2013) Interferon-gamma-mediated tissue factor expression contributes to T-cell-mediated hepatitis through induction of hypercoagulation in mice. Hepatology 57:362-372.
Levi M (2013) Pathogenesis and management of peripartum coagulopathic calamities (disseminated intravascular coagulation and amniotic fluid embolism). Thromb Res 131 Suppl 1:S32-34.
Likes K, Rochlin D, Nazarian SM, Streiff MB, Freischlag JA (2013) Females with subclavian vein thrombosis may have an increased risk of hypercoagulability. JAMA Surg 148:44-49.
Lo L, Valentine H, Harrison J, Hayes S, Welch I, Pritchard S, . . . Ang Y (2012) Tissue factor expression in the metaplasia-adenoma-carcinoma sequence of gastric cancer in a European population. Br J Cancer 107:1125-1130.
Maegele M (2013) Coagulopathy after traumatic brain injury: incidence, pathogenesis, and treatment options. Transfusion 53 Suppl 1:28S-37S.
Majumder R, Koklic T, Rezaie AR, Lentz BR (2013) Phosphatidylserine-induced factor Xa dimerization and binding to factor Va are competing processes in solution. Biochemistry 52:143-151.
Maroney SA, Ellery PE, Wood JP, Ferrel JP, Martinez ND, Mast AE (2013) Comparison of the inhibitory activity of human TFPIalpha and TFPIbeta. J Thromb Haemost.
Ogawa M, Akahira S, Takahashi S, Shimoda Y, Sato M, Sato A, Terada Y (2013) Low-dose recombinant activated factor VII temporally stopped bleeding from small artery in severe postpartum hemorrhage: a case report. Blood Coagul Fibrinolysis.
Palojarvi A, Andersson S, Langstrom S, Petaja J (2013) Coordinated release of tissue factor and tissue factor pathway inhibitor in VLBW infants. Acta Paediatr.
Pawlak K, Ulazka B, Mysliwiec M, Pawlak D (2012) Vascular endothelial growth factor and uPA/suPAR system in early and advanced chronic kidney disease patients: a new link between angiogenesis and hyperfibrinolysis? Transl Res 160:346-354.
Priestley ES, De Lucca I, Zhou J, Zhou J, Saiah E, Stanton R, . . . Wexler RR (2013) Discovery and gram-scale synthesis of BMS-593214, a potent, selective FVIIa inhibitor. Bioorg Med Chem Lett.
Sadeghi N, Kahn D, Jeske W, Hoppensteadt D, Fareed J (2013) Tissue Factor-Mediated Activation of the Prothrombin Complex Concentrate (PCC) is Differently Inhibited by Dabigatran, Rivaroxaban, and Apixaban: Potential Clinical Implication. Clin Appl Thromb Hemost.
Scheffert JL, Taber DJ, Pilch NA, McGillicuddy JW, Baliga PK, Chavin KD (2013) Timing of Factor VIIa in Liver Transplantation Impacts Cost and Clinical Outcomes. Pharmacotherapy.
Schulman S (1999) Haemostatic and replacement therapy in von Willebrand disease. Haemophilia 5 Suppl 2:57-59.
Shi W, Mei H, Deng J, Chen C, Wang H, Guo T, . . . Hu Y (2013) The delivery of thrombi-specific nanoparticles incorporating oligonucleotides into injured cerebrovascular endothelium. Biomaterials.
Song KD, Dowd SE, Lee HK, Kim SW (2013) Long-term dietary supplementation of organic selenium modulates gene expression profiles in leukocytes of adult pigs. Anim Sci J 84:238-246.
Teitel JM, Sholzberg M (2013) Current status and future prospects for the prophylactic management of hemophilia patients with inhibitor antibodies. Blood Rev 27:103-109.
Vadivel K, Agah S, Messer AS, Cascio D, Bajaj MS, Krishnaswamy S, . . . Bajaj SP (2013) Structural and Functional Studies of gamma-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium. J Mol Biol.
Vigren P, Strom JO, Petrini P, Callander M, Theodorsson A (2012) Treatment of spontaneous intracerebral haemorrhage in Glanzmann's thrombasthenia. Haemophilia 18:e381-383.
Xia L, Zhou H, Hu L, Xie H, Wang T, Xu Y, . . . Yan J (2013) Both NF-kappaB and c-Jun/AP-1 involved in anti-beta2GPI/beta2GPI-induced tissue factor expression in monocytes. Thromb Haemost 109.
Yajun E, He N, Fan H (2013) The Effect of Short-term Intra-arterial Delivery of Paclitaxel on Neointimal Hyperplasia and the Local Thrombotic Environment after Angioplasty. Cardiovasc Intervent Radiol.
Yu X, Zheng L, Xiong SL, Cai Z, Wang Q (2011) [Effect of simulated microgravity on human monocytic cell proliferation and tissue factor mRNA expression]. Nan Fang Yi Ke Da Xue Xue Bao 31:1020-1022.
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TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
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