TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 19 October 3, 2011
__________________________________________________________
TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________
None submitted for this issue.
__________________________________________________________
POSITIONS SOUGHT/AVAILABLE
Haematologic Technologies, Inc. in Essex Junction, VT is looking for laboratory technicians and PhD scientists to help us grow. Experience in protein chemistry and protein purification required. Please see our job posting on our website here:
http://www.haemtech.com/news.htm
__________________________________________________________
UPCOMING SCIENTIFIC MEETINGS
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
__________________________________________________________
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 17, No. 19 October 3, 2011
(The next issue will be on October 17, 2011)
TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________
PAPERS IN PRESS
__________________________________________________________
POSITIONS SOUGHT/AVAILABLE
Haematologic Technologies, Inc. in Essex Junction, VT is looking for laboratory technicians and PhD scientists to help us grow. Experience in protein chemistry and protein purification required. Please see our job posting on our website here:
http://www.haemtech.com/news.htm
__________________________________________________________
UPCOMING SCIENTIFIC MEETINGS
- 53rd ASH Annual Meeting. San Diego, CA, USA, December 10-13, 2011 (abstract deadline is past): http://www.hematology.org/Meetings/Annual-Meeting/
- ATVB 2012 Scientific Sessions. Hilton Chicago, Chicago Illinois, April 18-20, 2012. Abstract deadline is January 5, 2012: http://my.americanheart.org/professional/Sessions/ATVB/ATVB_UCM_316902_SubHomePage.jsp
- 6th Symposium on Hemostasis: Special Focus on Tissue Factor, Factor VIIa and Tissue Factor Pathway Inhibitor. Carolina Inn, Chapel Hill, NC, May 3-5, 2012: http://www.med.unc.edu/www/events/6th-symposium-on-hemostasis
- 2012 Hemostasis Gordon Conference. Waterville Valley Resort, Waterville Valley, NH, July 22-27, 2012. Abstracts can be submitted for poster presentations: http://www.grc.org/programs.aspx?year=2012&program=hemostasis
- This meeting is preceded by a two-day "2012 Gordon Research Seminar on Hemostasis" (same site, July 21-22, 2012) for postdocs and graduate students: http://www.grc.org/programs.aspx?year=2012&program=grs_hemo
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1rExffZPU21QbyzIotgKoxH/
(2007) Utilization and Clinical Data on In-Hospital, Off-Label Uses of Recombinant Factor VIIa.
http://www.ncbi.nlm.nih.gov/pubmed/21938824
Abdel-Bakky MS, Hammad MA, Walker LA, Ashfaq MK (2011) Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice. Arch Toxicol 85:1245-1256.
http://www.ncbi.nlm.nih.gov/pubmed/21327618
Abel R, Salam NK, Shelley J, Farid R, Friesner RA, Sherman W (2011) Contribution of explicit solvent effects to the binding affinity of small-molecule inhibitors in blood coagulation factor serine proteases. ChemMedChem 6:1049-1066.
http://www.ncbi.nlm.nih.gov/pubmed/21506273
Agar C, de Groot PG, Marquart JA, Meijers JC (2011) Evolutionary conservation of the lipopolysaccharide binding site of beta2-glycoprotein I. Thromb Haemost 106.
http://www.ncbi.nlm.nih.gov/pubmed/21947351
Ando K, Ishibashi T, Ohkawara H, Inoue N, Sugimoto K, Uekita H, . . . Takeishi Y (2011) Crucial Role of Membrane Type 1 Matrix Metalloproteinase (MT1- MMP) in RhoA/Rac1-Dependent Signaling Pathways in Thrombin- Stimulated Endothelial Cells. J Atheroscler Thromb 18:762-773.
http://www.ncbi.nlm.nih.gov/pubmed/21628952
Blank M, Baraam L, Eisenstein M, Fridkin M, Dardik R, Heldman Y, . . . Shoenfeld Y (2011) beta2-Glycoprotein-I based peptide regulate endothelial-cells tissue-factor expression via negative regulation of pGSK3beta expression and reduces experimental-antiphospholipid-syndrome. J Autoimmun 37:8-17.
http://www.ncbi.nlm.nih.gov/pubmed/21524885
Butros L, Boayue K, Mathew P (2011) Current difficulties and recent advances in bypass therapy for the management of hemophilia with inhibitors: a new and practical formulation of recombinant factor VIIa. Drug Des Devel Ther 5:275-282.
http://www.ncbi.nlm.nih.gov/pubmed/21625417
Campello E, Spiezia L, Radu CM, Bulato C, Castelli M, Gavasso S, Simioni P (2011) Endothelial, platelet, and tissue factor-bearing microparticles in cancer patients with and without venous thromboembolism. Thromb Res 127:473-477.
http://www.ncbi.nlm.nih.gov/pubmed/21256535
Carlsson K, Persson E, Lindgren M, Carlsson U, Svensson M (2011) Effects on the conformation of FVIIa by sTF and Ca(2+) binding: Studies of fluorescence resonance energy transfer and quenching. Biochem Biophys Res Commun.
http://www.ncbi.nlm.nih.gov/pubmed/21924243
Cheng J, Xu J, Duanmu J, Zhou H, Booth CJ, Hu Z (2011) Effective Treatment of Human Lung Cancer by Targeting Tissue Factor with a Factor VII-Targeted Photodynamic Therapy. Curr Cancer Drug Targets.
http://www.ncbi.nlm.nih.gov/pubmed/21933104
Chu AJ (2011) Tissue factor, blood coagulation, and beyond: an overview. Int J Inflam 2011:367284.
http://www.ncbi.nlm.nih.gov/pubmed/21941675
De Rop C, Stadler M, Buchholz S, Eisert R, Ganser A, Trummer A (2011) Evaluation of tissue factor bearing microparticles as biomarkers in allogeneic stem-cell transplantation. Transplantation 92:351-358.
http://www.ncbi.nlm.nih.gov/pubmed/21681142
Di Nisio M, Baudo F, Cosmi B, D'Angelo A, De Gasperi A, Malato A, . . . Squizzato A (2011) Diagnosis and treatment of disseminated intravascular coagulation: Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET). Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/21930293
Dieterich M, Mann E, Wagner KF, Kramer-Steiner B, Reimer T, Gerber B, Stubert J (2011) Desmopressin-induced Moschcowitz-like syndrome after treatment of uterine atonic bleeding in a 28-year-old pregnant woman: case report and overview of the literature. Blood Coagul Fibrinolysis.
http://www.ncbi.nlm.nih.gov/pubmed/21921792
Ding L, Ma W, Littmann T, Camp R, Shen J (2011) The P2Y(2) nucleotide receptor mediates tissue factor expression in human coronary artery endothelial cells. J Biol Chem 286:27027-27038.
http://www.ncbi.nlm.nih.gov/pubmed/21652710
Disse J, Ruf W (2011) The endothelial protein C receptor is required for tissue factor ternary complex signaling in the mouse. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/21951329
Eisenreich A, Boltzen U, Malz R, Schultheiss HP, Rauch U (2011) Overexpression of alternatively spliced tissue factor induces the pro-angiogenic properties of murine cardiomyocytic HL-1 cells. Circ J 75:1235-1242.
http://www.ncbi.nlm.nih.gov/pubmed/21389637
Ettelaie C, Fountain D, Collier ME, Elkeeb AM, Xiao YP, Maraveyas A (2011) Low molecular weight heparin downregulates tissue factor expression and activity by modulating growth factor receptor-mediated induction of nuclear factor-kappaB. Biochim Biophys Acta.
http://www.ncbi.nlm.nih.gov/pubmed/21946214
Fang WQ, Zhang Q, Peng YB, Chen M, Lin XP, Wu JH, . . . Jin H (2011) Resistin level is positively correlated with thrombotic complications in Southern Chinese metabolic syndrome patients. J Endocrinol Invest 34:e36-42.
http://www.ncbi.nlm.nih.gov/pubmed/20671416
Gerotziafas GT, Galea V, Mbemba E, Kartechi A, Sassi M, Baccouche H, . . . Elalamy I (2011) Tissue factor over-expression by human pancreatic cancer cells BXPC3 is related to higher prothrombotic potential as compared to breast cancer cells MCF7. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/21917301
Henriquez S, Calderon C, Quezada M, Oliva B, Bravo ML, Aranda E, . . . Owen GI (2011) Progesterone utilizes distinct membrane pools of tissue factor to increase coagulation and invasion and these effects are inhibited by TFPI. J Cell Physiol.
http://www.ncbi.nlm.nih.gov/pubmed/21344386
Herrera RN, de Amaya EI, Aguilar RC, Turoni CJ, Maranon R, Berman SG, . . . de Bruno MP (2011) Inflammatory and prothrombotic activation with conserved endothelial function in patients with chronic, asymptomatic chagas disease. Clin Appl Thromb Hemost 17:502-507.
http://www.ncbi.nlm.nih.gov/pubmed/20699256
Holmberg H, Kiersgaard MK, Mikkelsen LF, Tranholm M (2011) Impact of blood sampling technique on blood quality and animal welfare in haemophilic mice. Lab Anim 45:114-120.
http://www.ncbi.nlm.nih.gov/pubmed/21382833
Holy EW, Forestier M, Richter EK, Akhmedov A, Leiber F, Camici GG, . . . Tanner FC (2011) Dietary alpha-linolenic acid inhibits arterial thrombus formation, tissue factor expression, and platelet activation. Arterioscler Thromb Vasc Biol 31:1772-1780.
http://www.ncbi.nlm.nih.gov/pubmed/21571683
Hvas AM, Boas TW, Jensen M, Lindskov C, Folkersen L, Ravn HB (2011) Change in Hemostatic Intervention After Implementation of Thromboelastometry. J Cardiothorac Vasc Anesth.
http://www.ncbi.nlm.nih.gov/pubmed/21924638
Ignjatovic V, Than J, Summerhayes R, Newall F, Horton S, Cochrane A, Monagle P (2011) Hemostatic response in paediatric patients undergoing cardiopulmonary bypass surgery. Pediatr Cardiol 32:621-627.
http://www.ncbi.nlm.nih.gov/pubmed/21360266
Jurk K, Lahav J, Van Aken H, Brodde MF, Nofer JR, Kehrel BE (2011) Extracellular Protein Disulfide Isomerase Regulates Feedback Activation of Platelet Thrombin Generation Via Modulation of Coagulation Factor Binding. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/21929690
Kacka K, Kacki W, Merak J, Bleka A (2010) Use of recombinant activated factor VII for reduction of perioperative blood loss during elective surgical correction of spine deformity in a Jehovah's Witness. Case report. Ortop Traumatol Rehabil 12:448-458.
http://www.ncbi.nlm.nih.gov/pubmed/21057153
Karkouti K, Levy JH (2011) Commentary: Recombinant Activated Factor VII: The Controversial Conundrum Regarding Its Off-Label Use. Anesth Analg 113:711-712.
http://www.ncbi.nlm.nih.gov/pubmed/21788315
Kassel KM, Owens III AP, Rockwell CE, Sullivan BP, Wang R, Tawfik O, . . . Luyendyk JP (2011) Protease-Activated Receptor 1 and Hematopoietic Cell Tissue Factor Are Required for Hepatic Steatosis in Mice Fed a High-Fat Diet. Am J Pathol.
http://www.ncbi.nlm.nih.gov/pubmed/21907177
Lee CN, Heidbrink JL, McKinnon K, Bushman V, Olsen H, Fitzhugh W, . . . Moore PA (2011) RNA Interference Characterization of Proteins Discovered by Proteomic Analysis of Pancreatic Cancer Reveals Function in Cell Growth and Survival. Pancreas.
http://www.ncbi.nlm.nih.gov/pubmed/21934552
Lhermusier T, Van Rottem J, Garcia C, Xuereb JM, Ragab A, Martin V, . . . Payrastre B (2011) The Syk-kinase inhibitor R406 impairs platelet activation and monocyte tissue factor expression triggered by heparin-PF4 complex directed antibodies. J Thromb Haemost 9:2067-2076.
http://www.ncbi.nlm.nih.gov/pubmed/21848694
Liang HP, Brophy TM, Hogg PJ (2011) Redox properties of the tissue factor Cys186-Cys209 disulfide bond. Biochem J 437:455-460.
http://www.ncbi.nlm.nih.gov/pubmed/21595632
Lima LG, Oliveira AS, Campos LC, Bonamino M, Chammas R, Werneck C, . . . Monteiro RQ (2011) Malignant transformation in melanocytes is associated with increased production of procoagulant microvesicles. Thromb Haemost 106:712-723.
http://www.ncbi.nlm.nih.gov/pubmed/21800005
Lisman T, Porte RJ (2011) Recombinant factor VIIa to treat severe bleeding in patients with liver disease: Pitfalls and possibilities. J Hepatol 55:950-951.
http://www.ncbi.nlm.nih.gov/pubmed/21925325
Luo D, Szaba FM, Kummer LW, Plow EF, Mackman N, Gailani D, Smiley ST (2011) Protective roles for fibrin, tissue factor, plasminogen activator inhibitor-1, and thrombin activatable fibrinolysis inhibitor, but not factor XI, during defense against the gram-negative bacterium Yersinia enterocolitica. J Immunol 187:1866-1876.
http://www.ncbi.nlm.nih.gov/pubmed/21724997
Luporsi P, Chopard R, Janin S, Racadot E, Bernard Y, Ecarnot F, . . . Schiele F (2011) Use of recombinant factor VIIa (NovoSeven((R))) in 8 patients with ongoing life-threatening bleeding treated with fondaparinux. Acute Card Care 13:93-98.
http://www.ncbi.nlm.nih.gov/pubmed/21517672
Ma Z, Zhang T, Wang R, Cheng Z, Xu H, Li W, . . . Wang X (2011) Tissue factor-factor VIIa complex induces epithelial ovarian cancer cell invasion and metastasis through a monocytes-dependent mechanism. Int J Gynecol Cancer 21:616-624.
http://www.ncbi.nlm.nih.gov/pubmed/21543928
Marchetti M, Russo L, Balducci D, Falanga A (2011) All trans-retinoic acid modulates the procoagulant activity of human breast cancer cells. Thromb Res 128:368-374.
http://www.ncbi.nlm.nih.gov/pubmed/21458031
Martinez-Sales V, Vila V, Mico L, Contreras MT, Escandell A, Reganon E (2011) [Circulating endothelial cells and microparticles in patients with antiphospholipid antibodies]. Med Clin (Barc) 136:431-433.
http://www.ncbi.nlm.nih.gov/pubmed/21051055
Mast AE (2011) Alternatively spliced tissue factor pathway inhibitor: functional implications. Front Biosci (Schol Ed) 3:1457-1462.
http://www.ncbi.nlm.nih.gov/pubmed/21622281
Mazer CD, Leong-Poi H, Chhina T, Alfardan Z, Lapierre H, Wang Z, . . . Teitel J (2011) Recombinant factor VIIa affects anastomotic patency of vascular grafts in a rabbit model. J Thorac Cardiovasc Surg 142:418-423.
http://www.ncbi.nlm.nih.gov/pubmed/21281943
Meziani F, Delabranche X, Asfar P, Toti F (2010) Bench-to-bedside review: circulating microparticles--a new player in sepsis? Crit Care 14:236.
http://www.ncbi.nlm.nih.gov/pubmed/21067540
Mitrophanov AY, Reifman J (2011) Kinetic modeling sheds light on the mode of action of recombinant factor VIIa on thrombin generation. Thromb Res 128:381-390.
http://www.ncbi.nlm.nih.gov/pubmed/21641634
Morse BC, Dente CJ, Hodgman EI, Shaz BH, Nicholas JM, Wyrzykowski AD, . . . Feliciano DV (2011) The Effects of Protocolized Use of Recombinant Factor VIIa Within a Massive Transfusion Protocol in a Civilian Level I Trauma Center. Am Surg 77:1043-1049.
http://www.ncbi.nlm.nih.gov/pubmed/21944521
Nadir Y, Kenig Y, Drugan A, Shafat I, Brenner B (2011) An assay to evaluate heparanase procoagulant activity. Thromb Res 128:e3-e8.
http://www.ncbi.nlm.nih.gov/pubmed/21481923
Natorska J, Wypasek E, Grudzien G, Sobczyk D, Marek G, Filip G, . . . Undas A (2011) Does Diabetes Accelerate the Progression of Aortic Stenosis through Enhanced Inflammatory Response within Aortic valves? Inflammation.
http://www.ncbi.nlm.nih.gov/pubmed/21935671
Naumnik B, Rydzewska-Rosolowska A, Mysliwiec M (2011) Different Effects of Enoxaparin, Nadroparin, and Dalteparin on Plasma TFPI During Hemodialysis: A Prospective Crossover Randomized Study. Clin Appl Thromb Hemost 17:480-486.
http://www.ncbi.nlm.nih.gov/pubmed/20682597
Oehmcke S, Morgelin M, Malmstrom J, Linder A, Chew M, Thorlacius H, Herwald H (2011) Stimulation of blood mononuclear cells with bacterial virulence factors leads to the release of pro-coagulant and pro-inflammatory microparticles. Cell Microbiol.
http://www.ncbi.nlm.nih.gov/pubmed/21951918
Ogiwara K, Nogami K, Shima M (2011) Factor VIII activation by factor VIIa analog (V158D/E296V/M298Q) in tissue factor-independent mechanisms. Thromb Haemost 106:665-674.
http://www.ncbi.nlm.nih.gov/pubmed/21901232
Perez-Ferrer A, Gredilla E, de Vicente J, Laporta Y (2011) Cardiac Surgery Without Blood Products in a Jehovah's Witness Child With Factor VII Deficiency. J Cardiothorac Vasc Anesth.
http://www.ncbi.nlm.nih.gov/pubmed/21924639
Pinazo MJ, Tassies D, Munoz J, Fisa R, de Jesus Posada E, Monteagudo J, . . . Gascon J (2011) Hypercoagulability biomarkers in Trypanosoma cruzi -infected patients. Thromb Haemost 106:617-623.
http://www.ncbi.nlm.nih.gov/pubmed/21866301
Raffa S, Reverter JC, Seijo S, Tassies D, Abraldes JG, Bosch J, Garcia-Pagan JC (2011) Hypercoagulability in Patients with Chronic Non-Cirrhotic Portal Vein Thrombosis. Clin Gastroenterol Hepatol.
http://www.ncbi.nlm.nih.gov/pubmed/21946303
Sakai T, Inoue S, Takei M, Ogawa G, Hamazaki Y, Ota H, Koboyashi Y (2011) Activated inflammatory cells participate in thrombus size through tissue factor and plasminogen activator inhibitor-1 in acute coronary syndrome: Immunohistochemical analysis. Thromb Res 127:443-449.
http://www.ncbi.nlm.nih.gov/pubmed/21388659
Schmid D, Svoboda M, Sorgner A, Moravcevic I, Thalhammer T, Chiba P, Moslinger T (2011) Glibenclamide reduces proinflammatory cytokines in an ex vivo model of human endotoxinaemia under hypoxaemic conditions. Life Sci.
http://www.ncbi.nlm.nih.gov/pubmed/21925514
Silveira A, Scanavini D, Boquist S, Ericsson CG, Hellenius ML, Leander K, . . . Hamsten A (2011) Relationships of plasma factor VIIa-antithrombin complexes to manifest and future cardiovascular disease. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/21925715
Skolnick BE, Shenouda M, Khutoryansky NM, Pusateri AE, Gabriel D, Carr ME (2011) Reversal of Clopidogrel-Induced Bleeding with rFVIIa in Healthy Subjects: A Randomized, Placebo-Controlled, Double-Blind, Exploratory Study. Anesth Analg 113:703-710.
http://www.ncbi.nlm.nih.gov/pubmed/21890888
Srinivasan R, Ozhegov E, Van den Berg YW, Aronow BJ, Franco RS, Palascak MB, . . . Bogdanov VY (2011) Splice variants of tissue factor promote monocyte-endothelial interactions by triggering the expression of cell adhesion molecules via integrin-mediated signaling. J Thromb Haemost 9:2087-2096.
http://www.ncbi.nlm.nih.gov/pubmed/21812913
Szmurlo D, Derylo L, Rys P, Wladysiuk M (2011) [Health economics of inhibitor bypassing agents in haemophilia A-activated prothrombin complex concentrate (aPCC) and recombinant activated factor VIIa (rFVIIa)]. Pol Merkur Lekarski 30:202-207.
http://www.ncbi.nlm.nih.gov/pubmed/21544998
Takeuchi H, Fernandez-Valdivia RC, Caswell DS, Nita-Lazar A, Rana NA, Garner TP, . . . Haltiwanger RS (2011) Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase. Proc Natl Acad Sci U S A.
http://www.ncbi.nlm.nih.gov/pubmed/21949356
Taniguchi M, Ono N, Hayashi A, Yakura Y, Takeya H (2011) Effect of dibutyryl cyclic adenosine monophosphate on the gene expression of plasminogen activator inhibitor-1 and tissue factor in adipocytes. Thromb Res 128:375-380.
http://www.ncbi.nlm.nih.gov/pubmed/21496886
Teruel R, Perez-Sanchez C, Corral J, Herranz MT, Perez-Andreu V, Saiz E, . . . Martinez C (2011) Identification of miRNAs as potential modulators of tissue factor expression in patients with systemic lupus erythematosus and antiphospholipid syndrome. J Thromb Haemost 9:1985-1992.
http://www.ncbi.nlm.nih.gov/pubmed/21794077
Tetik S, Ak K, Sahin Y, Gulsoy O, Isbir S, Arsan S, Yardimci T (2011) Postoperative statin therapy attenuates the intensity of systemic inflammation and increases fibrinolysis after coronary artery bypass grafting. Clin Appl Thromb Hemost 17:526-531.
http://www.ncbi.nlm.nih.gov/pubmed/20805103
Tse EY, Cheung WY, Ng KF, Luk KD (2011) Reducing perioperative blood loss and allogeneic blood transfusion in patients undergoing major spine surgery. J Bone Joint Surg Am 93:1268-1277.
http://www.ncbi.nlm.nih.gov/pubmed/21776581
Undas A, Jankowski M, Kaczmarek P, Sladek K, Brummel-Ziedins K (2011) Thrombin generation in chronic obstructive pulmonary disease: Dependence on plasma factor composition. Thromb Res 128:e24-28.
http://www.ncbi.nlm.nih.gov/pubmed/21624643
van den Hengel LG, Kocaturk B, Reitsma PH, Ruf W, Versteeg HH (2011) Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor. Blood 118:3446-3448.
http://www.ncbi.nlm.nih.gov/pubmed/21940832
van den Hengel LG, Versteeg HH (2011) Tissue factor signaling: a multi-faceted function in biological processes. Front Biosci (Schol Ed) 3:1500-1510.
http://www.ncbi.nlm.nih.gov/pubmed/21622285
Wertz D, Boveroux P, Peters P, Lenelle J, Franssen C (2011) Surgical resection of a sphenoid wing meningioma in a patient with Glanzmann thrombasthenia. Acta Anaesthesiol Belg 62:83-86.
http://www.ncbi.nlm.nih.gov/pubmed/21919374
Xu C, Deng F, Mao Z, Zhang J, Wang H, Wang J, . . . Ma D (2011) The interaction of the second Kunitz-type domain (KD2) of TFPI-2 with a novel interaction partner, prosaposin, mediates the inhibition of the invasion and migration of human fibrosarcoma cells. Biochem J.
http://www.ncbi.nlm.nih.gov/pubmed/21943334
Xu C, Gui Q, Chen W, Wu L, Sun W, Zhang N, . . . Fu X (2011) Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo. J Exp Clin Cancer Res 30:63.
http://www.ncbi.nlm.nih.gov/pubmed/21619686
Yates KR, Welsh J, Echrish HH, Greenman J, Maraveyas A, Madden LA (2011) Pancreatic cancer cell and microparticle procoagulant surface characterization: involvement of membrane-expressed tissue factor, phosphatidylserine and phosphatidylethanolamine. Blood Coagul Fibrinolysis.
http://www.ncbi.nlm.nih.gov/pubmed/21941170
Zheng XW, Kudaravalli R, Russell TT, Dimichele DM, Gibb C, Russell JE, . . . Pollak ES (2011) Mutation in the factor VII hepatocyte nuclear factor 4alpha-binding site contributes to factor VII deficiency. Blood Coagul Fibrinolysis 22:624-627.
http://www.ncbi.nlm.nih.gov/pubmed/21760481
__________________________________________________________
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1rExffZPU21QbyzIotgKoxH/
(2007) Utilization and Clinical Data on In-Hospital, Off-Label Uses of Recombinant Factor VIIa.
http://www.ncbi.nlm.nih.gov/pubmed/21938824
Abdel-Bakky MS, Hammad MA, Walker LA, Ashfaq MK (2011) Silencing of tissue factor by antisense deoxyoligonucleotide prevents monocrotaline/LPS renal injury in mice. Arch Toxicol 85:1245-1256.
http://www.ncbi.nlm.nih.gov/pubmed/21327618
Abel R, Salam NK, Shelley J, Farid R, Friesner RA, Sherman W (2011) Contribution of explicit solvent effects to the binding affinity of small-molecule inhibitors in blood coagulation factor serine proteases. ChemMedChem 6:1049-1066.
http://www.ncbi.nlm.nih.gov/pubmed/21506273
Agar C, de Groot PG, Marquart JA, Meijers JC (2011) Evolutionary conservation of the lipopolysaccharide binding site of beta2-glycoprotein I. Thromb Haemost 106.
http://www.ncbi.nlm.nih.gov/pubmed/21947351
Ando K, Ishibashi T, Ohkawara H, Inoue N, Sugimoto K, Uekita H, . . . Takeishi Y (2011) Crucial Role of Membrane Type 1 Matrix Metalloproteinase (MT1- MMP) in RhoA/Rac1-Dependent Signaling Pathways in Thrombin- Stimulated Endothelial Cells. J Atheroscler Thromb 18:762-773.
http://www.ncbi.nlm.nih.gov/pubmed/21628952
Blank M, Baraam L, Eisenstein M, Fridkin M, Dardik R, Heldman Y, . . . Shoenfeld Y (2011) beta2-Glycoprotein-I based peptide regulate endothelial-cells tissue-factor expression via negative regulation of pGSK3beta expression and reduces experimental-antiphospholipid-syndrome. J Autoimmun 37:8-17.
http://www.ncbi.nlm.nih.gov/pubmed/21524885
Butros L, Boayue K, Mathew P (2011) Current difficulties and recent advances in bypass therapy for the management of hemophilia with inhibitors: a new and practical formulation of recombinant factor VIIa. Drug Des Devel Ther 5:275-282.
http://www.ncbi.nlm.nih.gov/pubmed/21625417
Campello E, Spiezia L, Radu CM, Bulato C, Castelli M, Gavasso S, Simioni P (2011) Endothelial, platelet, and tissue factor-bearing microparticles in cancer patients with and without venous thromboembolism. Thromb Res 127:473-477.
http://www.ncbi.nlm.nih.gov/pubmed/21256535
Carlsson K, Persson E, Lindgren M, Carlsson U, Svensson M (2011) Effects on the conformation of FVIIa by sTF and Ca(2+) binding: Studies of fluorescence resonance energy transfer and quenching. Biochem Biophys Res Commun.
http://www.ncbi.nlm.nih.gov/pubmed/21924243
Cheng J, Xu J, Duanmu J, Zhou H, Booth CJ, Hu Z (2011) Effective Treatment of Human Lung Cancer by Targeting Tissue Factor with a Factor VII-Targeted Photodynamic Therapy. Curr Cancer Drug Targets.
http://www.ncbi.nlm.nih.gov/pubmed/21933104
Chu AJ (2011) Tissue factor, blood coagulation, and beyond: an overview. Int J Inflam 2011:367284.
http://www.ncbi.nlm.nih.gov/pubmed/21941675
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TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
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