TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 18, No. 6 March 15, 2012
__________________________________________________________
TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________
PAPERS IN PRESS
None submitted for this issue.
__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
__________________________________________________________
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 18, No. 6 March 15, 2012
(The next issue will be on April 2, 2012)
TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
__________________________________________________________
PAPERS IN PRESS
None submitted for this issue.
__________________________________________________________
RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1zAQvdLPoBG2iVEHhSfHOkV/
Aass HC, Ovstebo R, Troseid AM, Kierulf P, Berg JP, Henriksson CE (2011) Fluorescent particles in the antibody solution result in false TF- and CD14-positive microparticles in flow cytometric analysis. Cytometry A 79:990-999.
http://www.ncbi.nlm.nih.gov/pubmed/21990118
Ahrens HE, Petersen B, Queisser AL, Herrmann D, Kues W, Holler S, . . . Niemann H (2011) 232 generation of transgenic pigs carrying a small interfering RNA vector directed against tissue factor expression. Reprod Fertil Dev 24:228-229.
http://www.ncbi.nlm.nih.gov/pubmed/22394954
Aleman MM, Gardiner C, Harrison P, Wolberg AS (2011) Differential contributions of monocyte- and platelet-derived microparticles towards thrombin generation and fibrin formation and stability. J Thromb Haemost 9:2251-2261.
http://www.ncbi.nlm.nih.gov/pubmed/21883880
Alstrom U, Levin LA, Stahle E, Svedjeholm R, Friberg O (2012) Cost analysis of re-exploration for bleeding after coronary artery bypass graft surgery. Br J Anaesth 108:216-222.
http://www.ncbi.nlm.nih.gov/pubmed/22113929
Angelillo-Scherrer A (2012) Leukocyte-derived microparticles in vascular homeostasis. Circ Res 110:356-369.
http://www.ncbi.nlm.nih.gov/pubmed/22267840
Ay Y, Balkan C, Karapinar DY, Akin M, Bilenoglu B, Kavakli K (2012) Feasibility of Using Thrombin Generation Assay (TGA) for Monitoring Bypassing Agent Therapy in Patients With Hemophilia Having Inhibitors. Clin Appl Thromb Hemost.
http://www.ncbi.nlm.nih.gov/pubmed/22395575
Banz Y, Hess OM, Meier P, Korchagina EY, Gordeeva EA, Robson SC, . . . Rieben R (2012) Evaluation of Multimeric Tyrosine-O-Sulfate as a Cytoprotectant in an in vivo Model of Acute Myocardial Infarction in Pigs. Cardiology 121:59-70.
http://www.ncbi.nlm.nih.gov/pubmed/22398380
Bhagirath VC, O'Malley L, Crowther MA (2011) Management of bleeding complications in the anticoagulated patient. Semin Hematol 48:285-294.
http://www.ncbi.nlm.nih.gov/pubmed/22000094
Binny C, McIntosh J, Della Peruta M, Kymalainen H, Tuddenham EG, Buckley SM, . . . Nathwani AC (2012) AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage. Blood 119:957-966.
http://www.ncbi.nlm.nih.gov/pubmed/22134170
Butenas S, Krudysz-Amblo J (2012) Decryption of tissue factor. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22401800
Caviglia H, Candela M, Galatro G, Neme D, Moretti N, Bianco RP (2011) Elective orthopaedic surgery for haemophilia patients with inhibitors: single centre experience of 40 procedures and review of the literature. Haemophilia 17:910-919.
http://www.ncbi.nlm.nih.gov/pubmed/21342367
Chantrathammachart P, Pawlinski R (2012) Tissue factor and thrombin in sickle cell anemia. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22398014
Chapman AJ, Blount AL, Davis AT, Hooker RL (2011) Recombinant factor VIIa (NovoSeven RT) use in high risk cardiac surgery. Eur J Cardiothorac Surg 40:1314-1318; discussion 1318-1319.
http://www.ncbi.nlm.nih.gov/pubmed/21601468
Dargaud Y, Prevost C, Lienhart A, Claude Bordet J, Negrier C (2011) Evaluation of the overall haemostatic effect of recombinant factor VIIa by measuring thrombin generation and stability of fibrin clots. Haemophilia 17:957-961.
http://www.ncbi.nlm.nih.gov/pubmed/21453422
Emmerechts J, Loyen S, Hoylaerts MF (2012) Microparticle number or procoagulant activity are not upregulated in healthy elderly persons. Thromb Res 129:98-100.
http://www.ncbi.nlm.nih.gov/pubmed/21978658
Girolami A, Treleani M, Scarparo P, Bonamigo E, Lombardi AM (2012) Considerations on a Tentative Classification of FVII Deficiency Suited for Practical Clinical Purposes. Clin Appl Thromb Hemost.
http://www.ncbi.nlm.nih.gov/pubmed/22411998
Hacquard M, Durand M, Lecompte T, Boini S, Briancon S, Carteaux JP (2011) Off-label use of recombinant activated factor VII in intractable haemorrhage after cardiovascular surgery: an observational study of practices in 23 French cardiac centres (2005-7). Eur J Cardiothorac Surg 40:1320-1327.
http://www.ncbi.nlm.nih.gov/pubmed/21550261
Haeusler KG, Herm J, Hoppe B, Kasabov R, Malzahn U, Endres M, . . . Jungehulsing GJ (2012) Thrombophilia screening in young patients with cryptogenic stroke. Prevalence of gene polymorphisms compared to healthy blood donors and impact on secondary stroke prevention. Hamostaseologie 32.
http://www.ncbi.nlm.nih.gov/pubmed/22382799
Hammad MA, Abdel-Bakky MS, Walker LA, Ashfaq MK (2012) Tissue factor antisense deoxyoligonucleotide prevents monocrotaline/LPS hepatotoxicity in mice. J Appl Toxicol.
http://www.ncbi.nlm.nih.gov/pubmed/22407844
Hanson E, Kanse SM, Joshi A, Jood K, Nilsson S, Blomstrand C, Jern C (2012) Plasma FVII-activating protease (FSAP) antigen and activity levels are increased in ischemic stroke. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/22409238
Hibi K, Goto T, Shirahata A, Saito M, Kigawa G, Nemoto H, Sanada Y (2012) Methylation of TFPI2 No Longer Detected in the Serum DNA of Colorectal Cancer Patients after Curative Surgery. Anticancer Res 32:787-790.
http://www.ncbi.nlm.nih.gov/pubmed/22399594
Ivanciu L, Toso R, Margaritis P, Pavani G, Kim H, Schlachterman A, . . . Camire RM (2011) A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia. Nat Biotechnol 29:1028-1033.
http://www.ncbi.nlm.nih.gov/pubmed/22020385
Jouannelle C, Giansily-Blaizot M, Monpoux F, Casagrande F, Poiree M, Berard E (2012) Spontaneous umbilical cord haematoma and congenital factor VII deficiency. Haemophilia 18:e24-25.
http://www.ncbi.nlm.nih.gov/pubmed/21967451
Jurk K, Lahav J, H VANA, Brodde MF, Nofer JR, Kehrel BE (2011) Extracellular protein disulfide isomerase regulates feedback activation of platelet thrombin generation via modulation of coagulation factor binding. J Thromb Haemost 9:2278-2290.
http://www.ncbi.nlm.nih.gov/pubmed/21929690
Kanse SM, Declerck PJ, Ruf W, Broze G, Etscheid M (2012) Factor VII-activating protease promotes the proteolysis and inhibition of tissue factor pathway inhibitor. Arterioscler Thromb Vasc Biol 32:427-433.
http://www.ncbi.nlm.nih.gov/pubmed/22116096
Kasthuri RS, Glover SL, Jonas W, McEachron T, Pawlinski R, Arepally GM, . . . Mackman N (2012) PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcgammaRI. Blood.
http://www.ncbi.nlm.nih.gov/pubmed/22394597
Knudsen T, Kristensen AT, Nichols TC, Agerso H, Jensen AL, Kjalke M, . . . Tranholm M (2011) Pharmacokinetics, pharmacodynamics and safety of recombinant canine FVIIa in a study dosing one haemophilia A and one haemostatically normal dog. Haemophilia 17:962-970.
http://www.ncbi.nlm.nih.gov/pubmed/21645178
Koh YR, Cho SJ, Yeom SR, Chang CL, Lee EY, Son HC, Kim HH (2012) Evaluation of Recombinant Factor VIIa Treatment for Massive Hemorrhage in Patients with Multiple Traumas. Ann Lab Med 32:145-152.
http://www.ncbi.nlm.nih.gov/pubmed/22389882
Koizume S, Ito S, Miyagi E, Hirahara F, Nakamura Y, Sakuma Y, . . . Miyagi Y (2012) HIF2alpha-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells. Nucleic Acids Res.
http://www.ncbi.nlm.nih.gov/pubmed/22402494
Kolucki FR, Jr., Morris GJ, Thomas LC, Scialla S (2011) Factor VII deficiency in pregnancy and delivery: a case report. Haemophilia 17:e1005.
http://www.ncbi.nlm.nih.gov/pubmed/21492323
Lee HR, Jun HK, Kim HD, Lee SH, Choi BK (2012) Fusobacterium nucleatum GroEL induces risk factors of atherosclerosis in human microvascular endothelial cells and ApoE(-/-) mice. Mol Oral Microbiol 27:109-123.
http://www.ncbi.nlm.nih.gov/pubmed/22394469
Lee RD, Barcel DA, Williams JC, Wang JG, Boles JC, Manly DA, . . . Mackman N (2012) Pre-analytical and analytical variables affecting the measurement of plasma-derived microparticle tissue factor activity. Thromb Res 129:80-85.
http://www.ncbi.nlm.nih.gov/pubmed/21737126
Levi M, van der Poll T, Schultz M (2012) Infection and Inflammation as Risk Factors for Thrombosis and Atherosclerosis. Semin Thromb Hemost.
http://www.ncbi.nlm.nih.gov/pubmed/22399308
Lijnen HR, Van Hul M, Hemmeryckx B (2012) Caloric restriction improves coagulation and inflammation profile in obese mice. Thromb Res 129:74-79.
http://www.ncbi.nlm.nih.gov/pubmed/21689844
Liu B, Zhang L, Yang Q (2012) Genetics of intracerebral hemorrhage: Insights from candidate gene approaches. Neurol India 60:3-8.
http://www.ncbi.nlm.nih.gov/pubmed/22406772
Maksimovic B, Neretljak I, Vidas Z, Vojtusek IK, Tomulic K, Knotek M (2012) Treatment of bleeding after kidney biopsy with recombinant activated factor VII. Blood Coagul Fibrinolysis.
http://www.ncbi.nlm.nih.gov/pubmed/22395184
Mann KG, Krudysz-Amblo J, Butenas S (2012) Tissue factor controversies. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22401799
Mobarrez F, Egberg N, Antovic J, Broijersen A, Jorneskog G, Wallen H (2012) Release of endothelial microparticles in vivo during atorvastatin treatment; a randomized double-blind placebo-controlled study. Thromb Res 129:95-97.
http://www.ncbi.nlm.nih.gov/pubmed/22035651
Morfini M, Bjerre J (2011) Pharmacokinetics and safety of a 270 mcg kg-1 dose of room temperature stable recombinant activated factor VII in patients with haemophilia. Haemophilia 17:860-866.
http://www.ncbi.nlm.nih.gov/pubmed/21371194
Nakatomi Y, Tsuji M, Nakashima T, Gokudan S, Miyazaki H, Tomokiyo K, . . . Mogi M (2012) Pharmacokinetics, distribution, and excretion of 125I-labeled human plasma-derived-FVIIa and -FX with MC710 (FVIIa/FX mixture) in rats. Thromb Res 129:62-67.
http://www.ncbi.nlm.nih.gov/pubmed/21621824
Persson E (2012) Novel molecules for the correction of factor Xa generation and phenotype in hemophilia. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22405049
Petersen LC (2012) Hemostatic properties of a TFPI antibody. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22405586
Piek CJ, Brinkhof B, Teske E, Rothuizen J, Dekker A, Penning LC (2011) High intravascular tissue factor expression in dogs with idiopathic immune-mediated haemolytic anaemia. Vet Immunol Immunopathol 144:346-354.
http://www.ncbi.nlm.nih.gov/pubmed/21899896
Pinotti M, Bernardi F, Dal Mas A, Pagani F (2011) RNA-based therapeutic approaches for coagulation factor deficiencies. J Thromb Haemost 9:2143-2152.
http://www.ncbi.nlm.nih.gov/pubmed/21854538
Pisetsky DS, Ullal AJ, Gauley J, Ning TC (2012) Microparticles as mediators and biomarkers of rheumatic disease. Rheumatology (Oxford).
http://www.ncbi.nlm.nih.gov/pubmed/22403183
Rao LV, Kothari H, Pendurthi UR (2012) Tissue Factor encryption and decryption: Facts and controversies. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22398016
Rauch U (2012) Tissue factor and cardiomyocytes. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22398012
Reinhardt C, Bergentall M, Greiner TU, Schaffner F, Ostergren-Lunden G, Petersen LC, . . . Backhed F (2012) Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling. Nature.
http://www.ncbi.nlm.nih.gov/pubmed/22407318
Rodriguez-Merchan EC, Gomez-Cardero P, Jimenez-Yuste V (2012) Late avascular necrosis of the femoral head (anfh) after the percutaneous fixation of a non-displaced fracture of the femoral neck in a haemophilic patient with inhibitors: a non-reported association. Haemophilia 18:e4-5.
http://www.ncbi.nlm.nih.gov/pubmed/21752161
Ruf W (2012) Role of thiol pathways in TF procoagulant regulation. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22401798
Salaj P, Penka M, Smejkal P, Geierova V, Ovesna P, Brabec P, . . . Lindgren P (2012) Economic analysis of recombinant activated factor VII versus plasma-derived activated prothrombin complex concentrate in mild to moderate bleeds: Haemophilia registry data from the Czech Republic. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22386136
Sborov DW, Rodgers GM (2012) Acquired hemophilia a: a current review of autoantibody disease. Clin Adv Hematol Oncol 10:19-27.
http://www.ncbi.nlm.nih.gov/pubmed/22398803
Setty S, Reddell A, England A, Gomez K, Kadir R (2011) The role of recombinant factor VIIa for obstetric block in women with severe factor XI deficiency. Haemophilia 17:906-909.
http://www.ncbi.nlm.nih.gov/pubmed/21453421
Shirahata A, Fukutake K, Mimaya J, Takamatsu J, Shima M, Hanabusa H, . . . Saito H (2012) Clinical pharmacological study of a plasma-derived factor VIIa and factor X mixture (MC710) in haemophilia patients with inhibitors--phase I trial. Haemophilia 18:94-101.
http://www.ncbi.nlm.nih.gov/pubmed/21535327
Siboni SM, Zanon E, Sottilotta G, Consonni D, Castaman G, Mikovic D, . . . Peyvandi F (2012) Central nervous system bleeding in patients with rare bleeding disorders. Haemophilia 18:34-38.
http://www.ncbi.nlm.nih.gov/pubmed/21539694
Singh A, Boden G, Homko C, Gunawardana J, Rao AK (2012) Whole-Blood Tissue Factor Procoagulant Activity Is Elevated in Type 1 Diabetes and Effects of Hyperglycemia and Hyperinsulinemia. Diabetes Care.
http://www.ncbi.nlm.nih.gov/pubmed/22410811
Ten Cate H (2012) Tissue factor-driven thrombin generation and inflammation in atherosclerosis. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22398011
Tokgoz H, Caliskan U, Lavigne-Lissalde G, Giansily-Blaizot M (2012) Successful prophylactic use of recombinant activated factor VII (rFVIIa) in a patient with congenital FVII deficiency and inhibitors to FVII. Haemophilia 18:e25-27.
http://www.ncbi.nlm.nih.gov/pubmed/21973016
Tran H, Collecutt M, Whitehead S, Salem HH (2011) Prothrombin complex concentrates used alone in urgent reversal of warfarin anticoagulation. Intern Med J 41:337-343.
http://www.ncbi.nlm.nih.gov/pubmed/20403070
Tuttolomondo A, Di Raimondo D, Pecoraro R, Arnao V, Pinto A, Licata G (2012) Atherosclerosis as an Inflammatory Disease. Curr Pharm Des.
http://www.ncbi.nlm.nih.gov/pubmed/22390643
Uchida Y, Takeshita K, Yamamoto K, Kikuchi R, Nakayama T, Nomura M, . . . Murohara T (2012) Stress Augments Insulin Resistance and Prothrombotic State: Role of Visceral Adipose-Derived Monocyte Chemoattractant Protein-1. Diabetes.
http://www.ncbi.nlm.nih.gov/pubmed/22396205
van den Berg YW, Osanto S, Reitsma PH, Versteeg HH (2012) The relationship between tissue factor and cancer progression: insights from bench and bedside. Blood 119:924-932.
http://www.ncbi.nlm.nih.gov/pubmed/22065595
Van Den Berg YW, Reitsma PH (2011) Not exclusively tissue factor: neutrophil extracellular traps provide another link between chemotherapy and thrombosis. J Thromb Haemost 9:2311-2312.
http://www.ncbi.nlm.nih.gov/pubmed/21910822
Van Geffen M, Menegatti M, Loof A, Lap P, Karimi M, Laros-van Gorkom BA, . . . Van Heerde WL (2012) Retrospective evaluation of bleeding tendency and simultaneous thrombin and plasmin generation in patients with rare bleeding disorders. Haemophilia.
http://www.ncbi.nlm.nih.gov/pubmed/22404435
Warkentin TE, Margetts P, Connolly SJ, Lamy A, Ricci C, Eikelboom JW (2012) Recombinant factor VIIa (rFVIIa) and hemodialysis to manage massive dabigatran-associated postcardiac surgery bleeding. Blood 119:2172-2174.
http://www.ncbi.nlm.nih.gov/pubmed/22383791
Winckers K, Siegerink B, Duckers C, Maurissen LF, Tans G, Castoldi E, . . . Rosendaal FR (2011) Increased tissue factor pathway inhibitor activity is associated with myocardial infarction in young women: results from the RATIO study. J Thromb Haemost 9:2243-2250.
http://www.ncbi.nlm.nih.gov/pubmed/21895962
Wolberg AS, Aleman MM, Leiderman K, Machlus KR (2012) Procoagulant activity in hemostasis and thrombosis: Virchow's triad revisited. Anesth Analg 114:275-285.
http://www.ncbi.nlm.nih.gov/pubmed/22104070
Yu J, Zhao J, Liu W, Ge Z, Du Y (2011) Combined effects of irbesartan and carvedilol on expression of tissue factor and tissue factor pathway inhibitor in rats after myocardial infarction. Heart Vessels 26:646-653.
http://www.ncbi.nlm.nih.gov/pubmed/21229253
Zheng Y, Liu X, Guo SW (2012) Therapeutic potential of andrographolide for treating endometriosis. Hum Reprod.
http://www.ncbi.nlm.nih.gov/pubmed/22402211
__________________________________________________________
http://www.ncbi.nlm.nih.gov/sites/myncbi/collections/public/1zAQvdLPoBG2iVEHhSfHOkV/
Aass HC, Ovstebo R, Troseid AM, Kierulf P, Berg JP, Henriksson CE (2011) Fluorescent particles in the antibody solution result in false TF- and CD14-positive microparticles in flow cytometric analysis. Cytometry A 79:990-999.
http://www.ncbi.nlm.nih.gov/pubmed/21990118
Ahrens HE, Petersen B, Queisser AL, Herrmann D, Kues W, Holler S, . . . Niemann H (2011) 232 generation of transgenic pigs carrying a small interfering RNA vector directed against tissue factor expression. Reprod Fertil Dev 24:228-229.
http://www.ncbi.nlm.nih.gov/pubmed/22394954
Aleman MM, Gardiner C, Harrison P, Wolberg AS (2011) Differential contributions of monocyte- and platelet-derived microparticles towards thrombin generation and fibrin formation and stability. J Thromb Haemost 9:2251-2261.
http://www.ncbi.nlm.nih.gov/pubmed/21883880
Alstrom U, Levin LA, Stahle E, Svedjeholm R, Friberg O (2012) Cost analysis of re-exploration for bleeding after coronary artery bypass graft surgery. Br J Anaesth 108:216-222.
http://www.ncbi.nlm.nih.gov/pubmed/22113929
Angelillo-Scherrer A (2012) Leukocyte-derived microparticles in vascular homeostasis. Circ Res 110:356-369.
http://www.ncbi.nlm.nih.gov/pubmed/22267840
Ay Y, Balkan C, Karapinar DY, Akin M, Bilenoglu B, Kavakli K (2012) Feasibility of Using Thrombin Generation Assay (TGA) for Monitoring Bypassing Agent Therapy in Patients With Hemophilia Having Inhibitors. Clin Appl Thromb Hemost.
http://www.ncbi.nlm.nih.gov/pubmed/22395575
Banz Y, Hess OM, Meier P, Korchagina EY, Gordeeva EA, Robson SC, . . . Rieben R (2012) Evaluation of Multimeric Tyrosine-O-Sulfate as a Cytoprotectant in an in vivo Model of Acute Myocardial Infarction in Pigs. Cardiology 121:59-70.
http://www.ncbi.nlm.nih.gov/pubmed/22398380
Bhagirath VC, O'Malley L, Crowther MA (2011) Management of bleeding complications in the anticoagulated patient. Semin Hematol 48:285-294.
http://www.ncbi.nlm.nih.gov/pubmed/22000094
Binny C, McIntosh J, Della Peruta M, Kymalainen H, Tuddenham EG, Buckley SM, . . . Nathwani AC (2012) AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage. Blood 119:957-966.
http://www.ncbi.nlm.nih.gov/pubmed/22134170
Butenas S, Krudysz-Amblo J (2012) Decryption of tissue factor. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22401800
Caviglia H, Candela M, Galatro G, Neme D, Moretti N, Bianco RP (2011) Elective orthopaedic surgery for haemophilia patients with inhibitors: single centre experience of 40 procedures and review of the literature. Haemophilia 17:910-919.
http://www.ncbi.nlm.nih.gov/pubmed/21342367
Chantrathammachart P, Pawlinski R (2012) Tissue factor and thrombin in sickle cell anemia. Thromb Res.
http://www.ncbi.nlm.nih.gov/pubmed/22398014
Chapman AJ, Blount AL, Davis AT, Hooker RL (2011) Recombinant factor VIIa (NovoSeven RT) use in high risk cardiac surgery. Eur J Cardiothorac Surg 40:1314-1318; discussion 1318-1319.
http://www.ncbi.nlm.nih.gov/pubmed/21601468
Dargaud Y, Prevost C, Lienhart A, Claude Bordet J, Negrier C (2011) Evaluation of the overall haemostatic effect of recombinant factor VIIa by measuring thrombin generation and stability of fibrin clots. Haemophilia 17:957-961.
http://www.ncbi.nlm.nih.gov/pubmed/21453422
Emmerechts J, Loyen S, Hoylaerts MF (2012) Microparticle number or procoagulant activity are not upregulated in healthy elderly persons. Thromb Res 129:98-100.
http://www.ncbi.nlm.nih.gov/pubmed/21978658
Girolami A, Treleani M, Scarparo P, Bonamigo E, Lombardi AM (2012) Considerations on a Tentative Classification of FVII Deficiency Suited for Practical Clinical Purposes. Clin Appl Thromb Hemost.
http://www.ncbi.nlm.nih.gov/pubmed/22411998
Hacquard M, Durand M, Lecompte T, Boini S, Briancon S, Carteaux JP (2011) Off-label use of recombinant activated factor VII in intractable haemorrhage after cardiovascular surgery: an observational study of practices in 23 French cardiac centres (2005-7). Eur J Cardiothorac Surg 40:1320-1327.
http://www.ncbi.nlm.nih.gov/pubmed/21550261
Haeusler KG, Herm J, Hoppe B, Kasabov R, Malzahn U, Endres M, . . . Jungehulsing GJ (2012) Thrombophilia screening in young patients with cryptogenic stroke. Prevalence of gene polymorphisms compared to healthy blood donors and impact on secondary stroke prevention. Hamostaseologie 32.
http://www.ncbi.nlm.nih.gov/pubmed/22382799
Hammad MA, Abdel-Bakky MS, Walker LA, Ashfaq MK (2012) Tissue factor antisense deoxyoligonucleotide prevents monocrotaline/LPS hepatotoxicity in mice. J Appl Toxicol.
http://www.ncbi.nlm.nih.gov/pubmed/22407844
Hanson E, Kanse SM, Joshi A, Jood K, Nilsson S, Blomstrand C, Jern C (2012) Plasma FVII-activating protease (FSAP) antigen and activity levels are increased in ischemic stroke. J Thromb Haemost.
http://www.ncbi.nlm.nih.gov/pubmed/22409238
Hibi K, Goto T, Shirahata A, Saito M, Kigawa G, Nemoto H, Sanada Y (2012) Methylation of TFPI2 No Longer Detected in the Serum DNA of Colorectal Cancer Patients after Curative Surgery. Anticancer Res 32:787-790.
http://www.ncbi.nlm.nih.gov/pubmed/22399594
Ivanciu L, Toso R, Margaritis P, Pavani G, Kim H, Schlachterman A, . . . Camire RM (2011) A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia. Nat Biotechnol 29:1028-1033.
http://www.ncbi.nlm.nih.gov/pubmed/22020385
Jouannelle C, Giansily-Blaizot M, Monpoux F, Casagrande F, Poiree M, Berard E (2012) Spontaneous umbilical cord haematoma and congenital factor VII deficiency. Haemophilia 18:e24-25.
http://www.ncbi.nlm.nih.gov/pubmed/21967451
Jurk K, Lahav J, H VANA, Brodde MF, Nofer JR, Kehrel BE (2011) Extracellular protein disulfide isomerase regulates feedback activation of platelet thrombin generation via modulation of coagulation factor binding. J Thromb Haemost 9:2278-2290.
http://www.ncbi.nlm.nih.gov/pubmed/21929690
Kanse SM, Declerck PJ, Ruf W, Broze G, Etscheid M (2012) Factor VII-activating protease promotes the proteolysis and inhibition of tissue factor pathway inhibitor. Arterioscler Thromb Vasc Biol 32:427-433.
http://www.ncbi.nlm.nih.gov/pubmed/22116096
Kasthuri RS, Glover SL, Jonas W, McEachron T, Pawlinski R, Arepally GM, . . . Mackman N (2012) PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcgammaRI. Blood.
http://www.ncbi.nlm.nih.gov/pubmed/22394597
Knudsen T, Kristensen AT, Nichols TC, Agerso H, Jensen AL, Kjalke M, . . . Tranholm M (2011) Pharmacokinetics, pharmacodynamics and safety of recombinant canine FVIIa in a study dosing one haemophilia A and one haemostatically normal dog. Haemophilia 17:962-970.
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TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
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