Wednesday, February 26, 2014

Vol. 19, No. 19

TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 19, No. 19 October 1, 2013
(The next issue will be on October 15, 2013)
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TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
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ANNOUNCEMENTS
NEW SCIENTIFIC SOCIETY:
A new regional professional society dedicated to the advancement of thrombosis and hemostasis research, education and clinical care has been established: the North American Society on Thrombosis & Hemostasis (NASTH). Membership is free of charge. Formed in late 2012, NASTH's goal is to support both early career and experienced clinicians and scientists in the field primarily by organizing a regular scientific meeting. As the society develops and membership grows, it hopes to offer educational opportunities, including workshops, small meetings and webinars, and provide a mentoring program for junior members. For more information, go to:

NASTH's first scientific meeting is being organized in collaboration with the Thrombosis and Hemostasis Summit of North America (THSNA) in Chicago on April 10–12, 2014. Information on the Summit can be found at:

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PRODUCT ANNOUNCEMENT: 
Haematologic Technologies, Inc. supplies a full range of purified proteins and antibodies for use in thrombosis research.  These proteins include:

-- Purified human factor VIIa - purified from human plasma, and greater than 95% pure by SDS-PAGE.
Anti-VIIa is also available.

-- Recombinant human Tissue Factor - Fully functional, purified recombinant (Baculovirus) full -length Tissue factor.  http://www.haemtech.com/Other/TissueFactor.htm
Anti-TF is also available.

-- Corn Trypsin Inhibitor - for use in thrombin generation assays and for the study of TF-dependent pathway of coagulation.  http://www.haemtech.com/Inhibitors_Substrates/CTI.htm

Contact customer service (hti@haemtech.com) for additional information or simply visit our website via the links above. Please include "Trigger" in the subject line.
  
DISCLAIMER:  Commercial product announcements appearing in TRIGGER are provided "as is" for informational purposes only.  The editors of TRIGGER have not necessarily evaluated any materials from commercial suppliers described in this newsletter or on its web sites, and we certainly are not endorsing any specific suppliers or products.  Furthermore, the editors receive no revenues from any source in the course of publishing TRIGGER.
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PAPERS IN PRESS
None Submitted for this issue.
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UPCOMING MEETINGS & EVENTS
General info on upcoming meetings of interest:
http://tf7.org/meetings.htm

ISTH also maintains a list of upcoming meetings of interest:
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RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":

Baker JV (2013) Chronic HIV disease and activation of the coagulation system. Thromb Res.

Barratt-Due A, Thorgersen EB, Egge K, Pischke S, Sokolov A, Hellerud BC, . . . Mollnes TE (2013) Combined inhibition of complement C5 and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis. J Immunol 191:819-827.

Bernal-Lopez MR, Garrido-Sanchez L, Gomez-Carrillo V, Gallego-Perales JL, Llorente-Cortes V, Calleja F, . . . Tinahones FJ (2013) Antioxidized LDL antibodies are associated with different metabolic pathways in patients with atherosclerotic plaque and type 2 diabetes. Diabetes Care 36:1006-1011.

Butenas S, Gissel M, Krudysz-Amblo J, Mann KG (2013) The nature of lipopolysaccharide-stimulated monocyte tissue factor activity. Blood Coagul Fibrinolysis.

Chen H, Qi X, He C, Yin Z, Fan D, Han G (2013) Coagulation imbalance may not contribute to the development of portal vein thrombosis in patients with cirrhosis. Thromb Res 131:173-177.

Christersson C, Johnell M, Siegbahn A (2013) Evaluation of microparticles in whole blood by multicolour flow cytometry assay. Scand J Clin Lab Invest 73:229-239.

Corbonnois G, Martin M, Hacquard M, Levy B, Mertes PM, Lecompte T, Audibert G (2013) Fondaparinux reversal with activated prothrombin complex concentrate in anesthetised bleeding rats. Thromb Haemost 109:560-563.

Date K, Hall J, Greenman J, Maraveyas A, Madden LA (2013) Tumour and microparticle tissue factor expression and cancer thrombosis. Thromb Res 131:109-115.

David JS, Godier A, Dargaud Y, Inaba K (2013) Case scenario: management of trauma-induced coagulopathy in a severe blunt trauma patient. Anesthesiology 119:191-200.

Deutschmann A, Schlagenhauf A, Leschnik B, Hoffmann KM, Hauer A, Muntean W (2013) Increased procoagulant function of microparticles in pediatric inflammatory bowel disease: role in increased thrombin generation. J Pediatr Gastroenterol Nutr 56:401-407.

DeWalt RI, Petkovich DA, Zahrt AN, Bruns HA, McDowell SA (2013) Host cell invasion by Staphylococcus aureus stimulates the shedding of microvesicles. Biochem Biophys Res Commun 432:695-700.

Drobiecki A, Pasiarski M, Hus I, Sokolowska B, Watek M (2013) Acquired hemophilia in the patient suffering from rheumatoid arthritis: case report. Blood Coagul Fibrinolysis.

Engelbrecht S, Wood EM, Cole-Sinclair MF (2013) Clinical transfusion practice update:
haemovigilance, complications, patient blood management and national standards. Med J Aust 199:397-401.

Esmon CT (2013) Molecular circuits in thrombosis and inflammation. Thromb Haemost 109:416-420.

Fukushige S, Horii A (2013) DNA methylation in cancer: a gene silencing mechanism and the clinical potential of its biomarkers. Tohoku J Exp Med 229:173-185.

Gris JC (2013) [Off-label use of rhuFVIIa: Allegro ma non tropo.]. Ann Fr Anesth Reanim.

Karagiannis ED, Urbanska AM, Sahay G, Pelet JM, Jhunjhunwala S, Langer R, Anderson DG (2013) Rational Design of a Biomimetic Cell Penetrating Peptide Library. ACS Nano.

Kimura H, Uegaki M, Aoyama T, Miyoshi T, Nagai K, Hashimura T (2013) [Acquired hemophilia presenting as gross hematuria and perineal subcutaneous hemorrhage after prostate biopsy: a case report]. Hinyokika Kiyo 59:305-308.

King EG, Bauza GJ, Mella JR, Remick DG (2013) Pathophysiologic mechanisms in septic shock. Lab Invest.

Knappe S, Gorczyca ME, Jilma B, Derhaschnig U, Hartmann R, Palige M, . . . Dockal M (2013) Plasmatic tissue factor pathway inhibitor is a major determinant of clotting in factor VIII inhibited plasma or blood. Thromb Haemost 109:450-457.

Kumar MA (2013) Coagulopathy associated with traumatic brain injury. Curr Neurol Neurosci Rep 13:391.

Legrand M, Rossignol M, Muller F, Payen D (2013) [Amniotic fluid embolism: an update]. Ann Fr Anesth Reanim 32:189-197.

Llau JV, Ferrandis R, Castillo J, de Andres J, Gomar C, Gomez-Luque A, . . . Torres LM (2012) [Recommendations on use of direct oral anticoagulants in the perioperative period]. Med Clin (Barc) 139 Suppl 2:46-50.

Narverud I, Iversen PO, Aukrust P, Halvorsen B, Ueland T, Johansen SG, . . . Holven KB (2013) Maternal familial hypercholesterolaemia (FH) confers altered haemostatic profile in offspring with and without FH. Thromb Res 131:178-182.

Nayak RC, Keshava S, Esmon CT, Pendurthi UR, Rao LV (2013) Rab GTPases regulate endothelial cell protein C receptor-mediated endocytosis and trafficking of factor VIIa. PLoS One 8:e59304.

Ovstebo R, Hellum M, Aass HC, Troseid AM, Brandtzaeg P, Mollnes TE, Henriksson CE (2013) Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood. Innate Immun.

Peng W, Yu Y, Li T, Zhu Y, Chen H (2013) The effects of small interfering RNA-targeting tissue factor on an in vitro model of neovascularization. Mol Vis 19:1296-1303.

Prinz N, Clemens N, Canisius A, Lackner KJ (2013) Endosomal NADPH-oxidase is critical for induction of the tissue factor gene in monocytes and endothelial cells. Lessons from the antiphospholipid syndrome. Thromb Haemost 109:525-531.

Rogers WK, Wernimont SA, Kumar GC, Bennett E, Chestnut DH (2013) Acute hypotension associated with intraoperative cell salvage using a leukocyte depletion filter during management of obstetric hemorrhage due to amniotic fluid embolism. Anesth Analg 117:449-452.

Snir A, Brenner B, Paz B, Ohel G, Lanir N (2013) The role of fibrin matrices and tissue factor in early-term trophoblast proliferation and spreading. Thromb Res.

Stadnicki A (2013) Thrombin generation and microparticles in inflammatory bowel diseases. J Pediatr Gastroenterol Nutr 56:343.

Stanne TM, Hanson E, Olsson S, Hoglund J, Jood K, Blomstrand C, Jern C (2013) Factor VII antigen levels are differentially associated to etiological subtypes of ischaemic stroke. Thromb Haemost 110.

Summerhayes R (2013) Laboratory methods for the assay of tissue factor pathway inhibitor in human plasma. Methods Mol Biol 992:289-300.

Suzuki K, Sugawara T, Ishida Y, Suwabe A (2013) Compound heterozygous mutations (p.Leu13Pro and p.Tyr294*) associated with factor VII deficiency cause impaired secretion through ineffective translocation and extensive intracellular degradation of factor VII. Thromb Res 131:166-172.

Tang N, Yin S, Sun Z, Pan Y (2013) Time course of soluble P-selectin and von Willebrand factor levels in trauma patients: a prospective observational study. Scand J Trauma Resusc Emerg Med 21:70.

Thaler J, Preusser M, Ay C, Kaider A, Marosi C, Zielinski C, . . . Hainfellner JA (2013) Intratumoral tissue factor expression and risk of venous thromboembolism in brain tumor patients. Thromb Res 131:162-165.

Vaitkiene P, Skiriute D, Skauminas K, Tamasauskas A (2012) Associations between TFPI-2 methylation and poor prognosis in glioblastomas. Medicina (Kaunas) 48:345-349.

van den Hengel LG, van Steijn-van Tol AQ, Bertina RM, Versteeg HH, Osanto S (2013) Microparticle-associated tissue factor activity in plasma is unaffected by cytolytic chemotherapy treatment in metastatic testicular cancer patients. Thromb Res 131:187-189.

Vu TT, Fredenburgh JC, Weitz JI (2013) Zinc: an important cofactor in haemostasis and thrombosis. Thromb Haemost 109:421-430.

Wang X, Li L, Li M, Dang X, Wan L, Wang N, . . .Wang L (2013) Knockdown of mTOR by
lentivirusmediated RNA interference suppresses atherosclerosis and stabilizes plaques via a decrease of macrophages by autophagy in apolipoprotein Edeficient mice. Int J Mol Med 32:1215-1221.

Wisler JW, Becker RC (2013) Emerging paradigms in arterial thrombosis. J Thromb Thrombolysis. http://www.ncbi.nlm.nih.gov/pubmed/24046067
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ABOUT TRIGGER
TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.

DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
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