TRIGGER
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 19, No. 22 November 15, 2013
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TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
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UPCOMING MEETINGS & EVENTS
The Twice-Monthly Electronic Newsletter on the Biology of Tissue Factor, Factor VII and TFPI
Vol. 19, No. 22 November 15, 2013
(The next issue will be on December 2, 2013)
TRIGGER is also available by RSS Feed:
and BLOG:
http://trigger-tf7.blogspot.com/
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PAPERS IN PRESS
None Submitted for this issue.
__________________________________________________________None Submitted for this issue.
UPCOMING MEETINGS & EVENTS
General info on upcoming meetings of interest:
http://tf7.org/meetings.htm
POSITIONS SOUGHT/AVAILABLE
We are seeking a highly qualified and motivated individual for one Postdoctoral Position in the Division of Hematology at The Children's Hospital of Philadelphia in the laboratory of Dr. Paris Margaritis.
The Children's Hospital of Philadelphia in an Equal
Opportunity / Affirmative Action Employer. Women and minorities are encouraged to
apply.
ISTH also maintains a list of upcoming meetings of
interest:
POSITIONS SOUGHT/AVAILABLE
We are seeking a highly qualified and motivated individual for one Postdoctoral Position in the Division of Hematology at The Children's Hospital of Philadelphia in the laboratory of Dr. Paris Margaritis.
The research will be devoted to studying the biological
and therapeutic effects of blood coagulation factor expression in vitro or in
vivo in appropriate models. Applicants should have a strong background in
molecular biology and have experience working with transgenic/gene targeted
mouse and rat models. Those with experience in coagulation protein biochemistry
and tissue culture are strongly encouraged to apply. Candidates should have
successfully earned an advanced degree (M.D. or Ph.D.), have excellent
communications skills and be willing to work on a multidisciplinary team.
Highly competitive salary and benefits are offered. Curriculum vitae and the
names of three referees should be sent to: Dr. Paris Margaritis, The Children's
Hospital of Philadelphia, Division of Hematology, Colket Translational Research
Building, Rm 5024, 3501 Civic Center Blvd., Philadelphia, PA 19104 U.S.A.
Email: margaritis AT email DOT chop DOT edu
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RECENT PUBLICATIONS ON TISSUE FACTOR, FACTOR VII, AND TFPI
Papers are culled from NLM MedLine (PubMed). Titles in square brackets indicate that the paper was not published in English. References that lack volume or page numbers are typically electronic pre-publications (E-pubs) ahead of the print publication; if so, the final citation with volume and page numbers may or may not appear in a future issue of Trigger.
THE FOLLOWING LINK WILL TAKE YOU TO THE ENTIRE LIST OF THIS ISSUE'S PUBLICATIONS IN A PUBMED "COLLECTION":
Alabi CA, Love KT, Sahay G, Yin H, Luly KM, Langer R,
Anderson DG (2013) Multiparametric approach for the evaluation of
lipid nanoparticles for siRNA delivery. Proc Natl Acad Sci U S
A 110:12881-12886.
Amirkhosravi A, Bigsby Gt, Desai H, Rivera-Amaya M, Coll
E, Robles-Carrillo L, . . . Francis JL (2013) Blood clotting
activation analysis for preoperative differentiation of benign
versus malignant
ovarian masses. Blood Coagul Fibrinolysis 24:510-517.
Antoniak S, Mackman N (2013) Coagulation,
Protease-Activated Receptors, and Viral Myocarditis. J Cardiovasc Transl
Res.
Austin AW, Patterson SM (2013) Comparison of
stress-hemoconcentration correction techniques for stress-induced coagulation.
Biomed Res Int 2013:480648.
Balaoing LR, Post AD, Liu H, Minn KT, Grande-Allen KJ
(2013) Age-Related Changes in Aortic Valve Hemostatic Protein
Regulation. Arterioscler Thromb Vasc Biol.
Barras CD, Tress BM, Christensen S, Collins M, Desmond
PM, Skolnick BE, . . . Davis SM (2013) Quantitative CT densitometry
for predicting intracerebral hemorrhage growth. AJNR Am J Neuroradiol 34:1139-1144.
Butenas S (2013) Comparison of natural and recombinant
tissue factor proteins: new insights. Biol Chem 394:819-829.
Carr ME, Vickaryous B (2013) Life, limb or off-label
recombinant VIIa use in the setting of limited blood assets: a case study.
Blood Coagul Fibrinolysis 24:436-438.
Cruickshanks HA, Vafadar-Isfahani N, Dunican DS, Lee A,
Sproul D, Lund JN, . . . Tufarelli C (2013) Expression of a large
LINE-1-driven antisense RNA is linked to epigenetic silencing of the
metastasis
suppressor gene TFPI-2 in cancer. Nucleic Acids Res
41:6857-6869.
De Caterina R, Husted S, Wallentin L, Andreotti F,
Arnesen H, Bachmann F, . . . Weitz JI (2013) General mechanisms of
coagulation and targets of anticoagulants (Section I). Position Paper
of the ESC Working Group on Thrombosis--Task Force on Anticoagulants
in Heart Disease. Thromb Haemost 109:569-579.
Ehrlich HJ, Wong WY, Ewenstein BM, Dockal M, Turecek PL,
Gringeri A,. . . Reininger AJ (2013) Development of novel treatment
options for patients with haemophilia. Hamostaseologie 33 Suppl
1:S36-38.
Ferreira J, DeLosSantos M (2013) The clinical use of
prothrombin complex concentrate. J Emerg Med 44:1201-1210.
Franks Z, Campbell RA, Vieira de Abreu A, Holloway JT,
Marvin JE, Kraemer BF, . . . Rondina MT (2013) Methicillin-resistant Staphylococcus aureus-induced thrombo-inflammatory
response is
reduced with timely antibiotic administration. Thromb
Haemost 109:684-695.
Gaunt TR, Zabaneh D, Shah S, Guyatt A, Ladroue C, Kumari
M, . . . Day IN (2013) Gene-centric association signals for
haemostasis and thrombosis traits identified with the HumanCVD BeadChip.
Thromb Haemost 110:995-1003.
Geddings JE, Mackman N (2013) Tumor-derived tissue
factor-positive microparticles and venous thrombosis in cancer patients.
Blood 122:1873-1880.
Gheldof D, Mullier F, Chatelain B, Dogne JM, Chatelain C
(2013) Inhibition of tissue factor pathway inhibitor increases
the sensitivity of thrombin generation assay to procoagulant microvesicles. Blood Coagul Fibrinolysis 24:567-572.
Guo Y, G YHL, Apostolakis S (2013) Inflammatory
biomarkers and atrial fibrillation: potential role of inflammatory pathways in
the pathogenesis of atrial fibrillation-induced
thromboembolism. Curr
Vasc Pharmacol.
Guzzetta NA, Szlam F, Kiser AS, Fernandez JD, Szlam AD,
Leong T, Tanaka KA (2013) Augmentation of thrombin generation in
neonates undergoing cardiopulmonary bypass. Br J Anaesth.
Hardij J, Cecchet F, Berquand A, Gheldof D, Chatelain C,
Mullier F, . . . Dogne JM (2013) Characterisation of tissue
factor-bearing extracellular vesicles with AFM: comparison of
air-tapping-mode AFM and liquid Peak Force AFM. J Extracell Vesicles 2.
Hosoya Y, Matsumura M, Madoiwa S, Zuiki T, Matsumoto S,
Nunomiya S, . . . Yasuda Y (2013) Acquired hemophilia A caused by
factor VIII inhibitors: report of a case. Surg Today 43:670-674.
Jenkins P, Ekrol I, Lawson G (2013) Total knee
replacement in patients with haemophilia: the Scottish experience. Scott
Med J 58:223-227.
Kostousov V, Wang YW, Cotton BA, Wade CE, Holcomb JB,
Matijevic N (2013) Influence of resuscitation fluids, fresh frozen
plasma and antifibrinolytics on fibrinolysis in a
thrombelastography-based, in-vitro, whole-blood model. Blood Coagul Fibrinolysis
24:489-497.
Krishnan S, Wilson EM, Sheikh V, Rupert A, Mendoza D,
Yang J, . . . Sereti I (2013) Evidence for innate immune system
activation in HIV-1 infected elite controllers. J Infect Dis.
Kyriazi V, Theodoulou E (2013) Assessing the risk and
prognosis of thrombotic complications in cancer patients. Arch Pathol
Lab Med 137:1286-1295.
Metzner HJ, Pipe SW, Weimer T, Schulte S (2013) Extending
the pharmacokinetic half-life of coagulation factors by
fusion to recombinant albumin. Thromb Haemost 110:931-939.
Muthard RW, Diamond SL (2013) Side view thrombosis
microfluidic device with controllable wall shear rate and
transthrombus pressure gradient. Lab Chip 13:1883-1891.
Oku K, Amengual O, Zigon P, Horita T, Yasuda S, Atsumi T
(2013) Essential role of the p38 mitogen-activated protein
kinase pathway in tissue factor gene expression mediated by the phosphatidylserine-dependent antiprothrombin antibody.
Rheumatology (Oxford) 52:1775-1784.
Palla A, Rogers J, Singh S (2011) Life-threatening
retro-pharyngeal bleed in a case of systemic lupus erythematosus--an
uncommon but important evil of a common disease. BMJ Case Rep 2011.
Qiu P, Li Y, Shiloach J, Cui X, Sun J, Trinh L, . . .
Eichacker PQ (2013) Bacillus anthracis cell wall peptidoglycan but not
lethal or edema toxins produces changes consistent with
disseminated intravascular coagulation in a rat model. J Infect Dis
208:978-989.
Rancourt RC, Veress LA, Ahmad A, Hendry-Hofer TB, Rioux
JS, Garlick RB, White CW (2013) Tissue factor pathway inhibitor
prevents airway obstruction, respiratory failure and death due to sulfur
mustard analog inhalation. Toxicol Appl Pharmacol 272:86-95.
Raps M, Helmerhorst FM, Fleischer K, Dahm AE, Rosendaal
FR, Rosing J, . . . van Vliet HA (2013) The effect of different
hormonal contraceptives on plasma levels of free protein S and
free TFPI.
Thromb Haemost 109:606-613.
http://www.ncbi.nlm.nih.gov/pubmed/23407778
http://www.ncbi.nlm.nih.gov/pubmed/23407778
Rea CJ, Foley JH, Bevan DH, Sorensen B (2013) An in-vitro
assessment of tranexamic acid as an adjunct to rFVIII or rFVIIa
treatment in haemophilia A. Ann Hematol.
Reddy R, Hong Duong TT, Fairhall JM, Smee RI, Stoodley MA
(2013) Durable thrombosis in a rat model of arteriovenous
malformation treated with radiosurgery and vascular targeting. J
Neurosurg.
Rigby MR, Kamat P, Vats A, Heard M (2013) Controlling
intrathoracic hemorrhage on ECMO: help from Factor VIIa and Virchow.
Perfusion 28:201-206.
Segers O, Simioni P, Tormene D, Castoldi E (2013)
Influence of single nucleotide polymorphisms on thrombin generation in factor
V Leiden heterozygotes. Thromb Haemost 111.
Stampfli SF, Camici GG, Keller S, Rozenberg I, Arras M,
Schuler B, . . . Tanner FC (2013) Restraint stress enhances arterial
thrombosis in vivo - Role of the sympathetic nervous system. Stress.
Sternberg Z, Ghanim H, Gillotti KM, Tario JD, Jr.,
Munschauer F, Curl R, . . . Dandona P (2013) Flow cytometry and gene
expression profiling of immune cells of the carotid plaque and
peripheral blood.
Atherosclerosis 229:338-347.
Topaloglu O, Arslan MS, Karakose M, Ucan B, Ginis Z,
Cakir E, . . . Delibasi T (2013) Is There Any Association Between
Thrombosis and Tissue Factor Pathway Inhibitor Levels in Patients With
Vitamin D Deficiency? Clin Appl Thromb Hemost.
Tu J, Hu Z, Chen Z (2013) Endothelial gene expression and
molecular changes in response to radiosurgery in in vitro and in
vivo models of cerebral arteriovenous malformations. Biomed Res Int
2013:408253.
Vedantham S, Thiagarajan D, Ananthakrishnan R, Wang L,
Rosario R, Zou YS, . . . Ramasamy R (2013) Aldose Reductase drives
hyperacetylation of Egr-1 in hyperglycemia and consequent upregulation of proinflammatory and prothrombotic signals. Diabetes.
Whalley D, Skappak C, Lang E (2013) The Need To Clot: A
review of current management strategies for adverse bleeding events
with new oral anticoagulants. Minerva Anestesiol.
Winckers K, ten Cate H, Hackeng TM (2013) The role of
tissue factor pathway inhibitor in atherosclerosis and arterial
thrombosis. Blood Rev 27:119-132.
Xia L, Zhou H, Hu L, Xie H, Wang T, Xu Y, . . . Yan J (2013)
Both NF-kappaB and c-Jun/AP-1 involved in
anti-beta2GPI/beta2GPI-induced tissue factor expression in monocytes. Thromb Haemost
109:643-651.
Xie H, Sheng L, Zhou H, Yan J (2013) The role of TLR4 in pathophysiology of antiphospholipid syndrome-associated
thrombosis and pregnancy morbidity. Br J Haematol.
Yokota N, Zarpellon A, Chakrabarty S, Bogdanov VY, Gruber
A, Castellino FJ, . . . Ruf W (2013) Contributions of
thrombin targets to tissue factor-dependent metastasis in hyperthrombotic
mice. J
Thromb Haemost.
Yu Y, Millar CM (2013) Measurement of FIX activity in
plasma derived and recombinant concentrates: insights from thrombin
generation and activation-based assays. J Thromb Haemost.
Zieleskiewicz L, Pierrou C, Ragonnet B, Tourret M, Chau
C, Craighero F, . . . Leone M (2013) [Role of whole-body ultrasound in
severe pre-eclampsia and post-partum hemorrhage]. Can J Anaesth
60:796-802.
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TRIGGER is edited by Jim Morrissey and Pierre Neuenschwander, with editorial assistance by Genie Morrissey. It includes Abstracts of Papers in Press, Meeting Announcements, Positions Sought/Available,or any other pertinent item that subscribers may want to share with their colleagues. To submit an item for publication in Trigger, e-mail us. To request or cancel a subscription,or for more information about TRIGGER or the biology of tissue factor and factor VII, visit our web site. You can also contact us by mail: J.H. Morrissey, University of Illinois College of Medicine, 417 Med Sci Bldg MC-714, 506 S. Mathews Ave., Urbana, IL 61801, USA.
DISCLAIMER: TRIGGER is provided "as is" for information purposes only and without warranty of any kind, express or implied. Users shall assume the entire risk as to the accuracy and usefulness of information in TRIGGER. Opinions expressed here are not necessarily those of the editors or their employers. You may share TRIGGER with your scientific colleagues but you are not permitted to use it or its contents for commercial purposes.
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